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A review on $\delta$-structurable algebras

In this paper we give a review on $\delta$-structurable algebras. A connection between Malcev algebras and a generalization of $\delta$-structurable algebras is also given.

Two-Dimensional Correlation of Isotropic and Directional Diffusion Using NMR.

Diffusion nuclear magnetic resonance (NMR) is a powerful technique for studying porous media, but yields ambiguous results when the sample comprises multiple regions with different pore sizes, shapes, and orientations. Inspired by solid-state NMR techniques for correlating isotropic and anisotropic chemical shifts, we propose a diffusion NMR method to resolve said ambiguity. Numerical data inversi

History of oral contraceptive use in breast cancer patients: impact on prognosis and endocrine treatment response.

The purpose was to study oral contraceptive (OC) use in relation to breast cancer events and endocrine treatment response in a prospective population-based cohort, because it is unclear whether history of OC use impacts on prognosis in breast cancer patients. Between 2002 and 2011, 994 primary breast cancer patients without preoperative treatment were enrolled in Lund, Sweden and followed until De

TFEB: Pathogenic role and therapeutic target in Parkinson disease.

Parkinson disease (PD) is characterized by the progressive loss of nigral dopamine neurons and the presence of accumulations containing the disease-causing protein SNCA/α-synuclein. Here we review our recent findings describing how SNCA impairs the function of the master regulator of the autophagy-lysosomal pathway (ALP), the transcription factor EB (TFEB), and that genetic or pharmacological stim

The undulation force; theoretical results versus experimental demonstrations.

In 1978 Wolfgang Helfrich published a paper (Helfrich W. Z Naturforsch 1978; 33a:305) where he introduced the notion of an undulation force between bilayers. This is caused by thermal excitations of the bending modes being restricted by the presence of neighboring layers. Although there is now a consensus on the qualitative picture put forward by Helfrich there is still a debate concerning the qua

Inhaled Corticosteroid/Long-Acting beta(2)-Agonist Combination Therapy for Asthma: Attitudes of Specialists in Europe

Background: As new combinations of inhaled corticosteroids (ICSs) and long-acting beta(2)-agonists (LABAs) become available for the treatment of asthma, it will be important to determine criteria against which they can be evaluated. The aim of this study was to assess which attributes of combination therapy physicians consider most important. Methods: Primary and secondary care asthma specialists

U-Pb baddeleyite ages and geochemistry of dolerite dykes in the Bas Draa Inlier of the Anti-Atlas of Morocco: Newly identified 1380 Ma event in the West African Craton

In the Bas-Draa Inlier (Anti-Atlas, Morocco), the Paleoproterozoic basement which is cut by the Ediacaran Taourgha granite is also crosscut by numerous dykes of a variety of trends, mostly of uncertain age. Two doleritic dykes are dated by the ID-TIMS U-Pb method on baddeleyite and yield emplacement ages of 1381 +/- 8 Ma (MSWD = 0.84) and 1384 +/- 6 Ma (MSWD = 1.4) determined for a N135 degrees E

Thalamocortical abnormalities in auditory brainstem response patterns distinguish DSM-IV bipolar disorder type I from schizophrenia.

Bipolar disorder type I (BP-I) belongs to a spectrum of affective disorders that are expressed in many different ways and therefore can be difficult to distinguish from other conditions, especially unipolar depression, schizoaffective disorder, schizophrenia (SZ), but also anxiety and personality disorders. Since early diagnosis and treatment have shown to improve the long-term prognosis, compleme

The balance of serum matrix metalloproteinase-8 and its tissue inhibitor in acute coronary syndrome and its recurrence

Background: Matrix metalloproteinase-8 (MMP-8) is involved in the breakdown of the extracellular matrix increasing the vulnerability of atherosclerotic lesions. We analysed the diagnostic value of serum MMP-8 and tissue inhibitor of metalloproteinase-1 (TIMP-1) concentrations in acute coronary syndrome (ACS) and their prognostic value in ACS recurrence. Methods: The population comprised 343 patien

Coupling carbon allocation with leaf and root phenology predicts tree–grass partitioning along a savanna rainfall gradient

The relative complexity of the mechanisms underlying savanna ecosystem dynamics, in comparison to other biomes such as temperate and tropical forests, challenges the representation of such dynamics in ecosystem and Earth system models. A realistic representation of processes governing carbon allocation and phenology for the two defining elements of savanna vegetation (namely trees and grasses) may

The interplay between multiple predators and prey colour divergence

Evolutionary divergence in the coloration of toxic prey is expected when geographic variation in predator composition and behavior favours shifts in prey conspicuousness. A fundamental prediction of predator-driven colour divergence is that the local coloration should experience lower predation risk than novel prey phenotypes. The dorsal coloration of the granular poison frog varies gradually from

Last glacial vegetation of northern Eurasia

In order to investigate the potential role of vegetation changes in megafaunal extinctions during the later part of the last glacial stage and early Holocene (42-10 ka BP), the palaeovegetation of northern Eurasia and Alaska was simulated using the LPJ-GUESS dynamic vegetation model. Palaeoclimatic driving data were derived from simulations made for 22 time slices using the Hadley Centre Unified M

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity.

We aimed to validate genetic variants as instruments for insulin resistance and secretion, to characterise their association with intermediate phenotypes, and to investigate their role in T2D risk among normal-weight, overweight and obese individuals.We investigated the association of genetic scores with euglycaemic-hyperinsulinaemic clamp- and OGTT-based measures of insulin resistance and secreti

Rapid elimination kinetics of free PSA or human kallikrein-related peptidase 2 after initiation of gonadotropin-releasing hormone-antagonist treatment of prostate cancer: potential for rapid monitoring of treatment responses

Background: The utility of conventional prostate-specifi c antigen (PSA) measurements in blood for monitoring rapid responses to treatment for prostate cancer is limited because of its slow elimination rate. Prior studies have shown that free PSA (fPSA), intact PSA (iPSA) and human kallikrein-related peptidase 2 (hK2) are eliminated more rapidly after radical prostatectomy. In contrast, all three

Gastroesophageal reflux disease and chronic sinusitis: In search of an esophageal-nasal reflex

Background: This study was performed to explore whether or not a neural reflex linking the esophagus and the nasal airway exists, as a pathogenic mechanism accounting for the association between gastroesophageal reflux (GER) disease and chronic rhinosinusitis (CRS). A prospective trial of healthy human volunteers was performed. Methods: Ten healthy volunteers without GER or sinonasal disease were

Genetically Determined Height and Coronary Artery Disease

BACKGROUND The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear. METHODS We used a genetic approach to investigate the association between height and CAD, using 180 height-associated genetic variants. We tested the association between a change in genetically determined height of 1 SD (6.5 cm) with the risk of

Time-resolved spectroscopic study of photofragment fluorescence in methane/air mixtures and its diagnostic implications

In this work 80-picosecond laser pulses of 266-nm wavelength with intensities up to (2.0 +/- A 0.5) x 10(11) W/cm(2) were used for fragmentation of methane/air gas mixtures at ambient pressure and temperature. Emission spectra are, for the first time, studied with ultrahigh temporal resolution using a streak camera. Fluorescence spectra from CH(A(2)Delta-(XI)-I-2 , (BI)-I-2 (-)-(XI)-I-2 pound , (C