CITED1 is a non-DNA binding transcriptional co-regulator whose expression can distinguish the 'proliferative' from 'invasive' signature in the phenotype-switching model of melanoma. We have found that, in addition to other 'proliferative' signature genes, CITED1 expression is repressed by TGFβ while the 'invasive' signature genes are upregulated. In agreement, CITED1 positively correlates with MIT

Aim: Outcome is uncertain in infants born at 23-24 gestational weeks. The aim of the present study was to identify possible early predictors of outcome in these infants. Materials and Methods: Data from the Swedish medical birth register (MBR) for live-born infants with gestational ages (GAs) 23 and 24 weeks, born during the time-period 2000-2002, were analysed in relation to short-term outcomes,

UV-curable acrylates are the base for a large and growing product group within the coatings industry. Traditional chemical catalysis is poorly suited for acrylation reactions since these require low temperatures to avoid polymerization. In this study, immobilized Candida antarctica lipase B has been used to efficiently acrylate four polymers through transesterification of ethyl acrylate, via a sol

Background: To explore the patients' experiences during the three decades following repair of a nerve injury in the forearm and its consequences for daily life. Strategies that were used to facilitate adaptation were also investigated. Methods: Fifteen participants with a complete median and/or ulnar nerve injury repaired in the ages from 13-20 years were interviewed using a semi-structured interv

Recension av Hans Roth, Dagbok från östfronten : en tysk soldats liv och död.

The sustainable development of a software product depends on a number of groups working together to achieve a common goal. However, each of the groups interacts with the product in different ways, and can have conflicting aims and objectives. For example, developers trying to correct issues in the software architecture, which will impact future releases of the product, can be stopped by a project

Assessment of proliferation is important in female breast cancer and individual treatment decisions are based upon its results, especially in the lumina! subgroups. Gene expression analyses fail to group male breast cancer into the intrinsic subgroups previously established in female breast cancer. Even though proliferation has been shown to divide male breast cancer into molecular subgroups with

Abstract/Results. The paper discusses the results of three different studies. A study of 717 ninth grade students in eight schools located in different socio-economic environments show that students have a low degree of trust in dispute settlement forms available at school. When involved in conflicts or degrading treatment at school they avoid turning to the school for help. Students give themselv

Heterogeneous rare-gas clusters produced by a coexpansion of an argon/xenon mixture have been studied using synchrotron-radiation-based photoelectron spectroscopy. Both valence and Xe 4d(5/2) core-level photoelectron spectra were recorded for three different concentrations of the primary argon/xenon mixture and, for those mixtures, spectra were recorded at several different stagnation conditions.

Electro-optical spectral decoding is used as an online diagnostic tool at the MAX-lab test-FEL to characterize the arrival time of electrons relative to the seed-laser pulse, measure the jitter between them and to measure the relative width of the electron bunch in order to optimize compression. Frequency characteristics of the jitter are presented. The measurements are used to get information on

Thermally stimulated diffusion of Mn through thin layers of GaAs has been studied by x-ray photoemission. (Ga, Mn) As samples with 5 at% Mn were capped with 4, 6 and 8 monolayer (ML) GaAs, and Mn diffusing through the GaAs was trapped on the surface by means of amorphous As. It was found that the out-diffusion is completely suppressed for an 8 ML thick GaAs film. The short diffusion length is attr

Two new eudesmane derivatives (3 and 8) were isolated from the ethanol extract of the aerial parts of Kaunia lasiophthalma Griseb, together with 14 known eudesmane, germacrane, and guaiane sesquiterpenes, and four flavones. The structures and relative configurations of all the compounds were established by NMR spectroscopy and high-resolution mass spectrometry. The anticancer activity of sesquiter

Background: Critical needs for treatment trials in gastroesophageal reflux disease (GERD) include assessing response to treatment, evaluating symptom severity, and translation of symptom questionnaires into multiple languages. We evaluated the previously validated Reflux Disease Questionnaire (RDQ) for internal consistency, reliability, responsiveness to change during treatment and the concordance

I argue that it is not possible to give an adequate account, within a Scanlon-style contractualist moral theory of the moral duties to reciprocate benefits one has received from others and to compensate harms one has done to others. The problem, very simply put, is that there is no room within such a theory for the fact that the content of these obligations must be proportionate to the value of th

Background: Panic Disorder with or without Agoraphobia is a commonly occurring disorder affecting 2-3% of the population in Sweden. Untreated, panic disorder is a chronic condition that significantly increases the risk for psychiatric comorbidity, morbidity and mortality, employment difficulties, and healthcare utilization. Cognitive behavioural approaches are the recommended first-line treatment

Alm är en uppskattad komponent i stadsmiljöer och rekreationsskogar och ett potentiellt betydelsefullt trädslag för skogsbruket. Almar hyser ett stort antal rödlistade insekter, svampar, mossor och lavar, och är därmed ytterst värdefulla för den biologiska mångfalden i svenska ädellövsskogar. Alla våra almar, och samtidigt de arter som är beroende av dem, hotas dock allvarligt av almsjukan.