Aerosol-And propane bottles for consumers, including hairspray, lubricants, etc. were tested for exposure from fire. The tested bottles had a volume between 15- 400 ml of product mixed with propane and bottles with propane only containing 0.35, 0.45, 5 and 6 kg of propane. The aerosol-And propane bottles were exposed to a heptane pool fire, corresponding to properties of common available flammable

Osteopontin (OPN) is involved in various physiological processes and also implicated in multiple pathological states. It has been suggested that OPN may have a role in type 2 diabetes (T2D) by protecting pancreatic islets and interaction with incretins. However, the regulation and function of OPN in islets, especially in humans, remains largely unexplored. In this study, we performed our investiga

This paper contributes to the literature on internal migration by estimating parameters for push and pull factors by modelling the complete migration decision. Using data based on individuals linked between the complete Swedish censuses of 1880 and 1890, we consider both the push factors which determined whether an individual choose to leave their origin and the pulls factors which attracted migra

Contact allergy induced by certain chemicals is a common health concern, and several alternative methods have been developed to fulfill the requirements of European legislation with regard to hazard assessment of potential skin sensitizers. However, validated methods, which provide information about the potency of skin sensitizers, are still lacking. The cell-based assay Genomic Allergen Rapid Det

With the shift of focus of the regulatory bodies, from fixed process conditions towards flexible ones based on process understanding, model-based optimization is becoming an important tool for process development within the biopharmaceutical industry. In this paper, a multi-objective optimization study of separation of three insulin variants by reversed-phase chromatography (RPC) is presented. The

Rhinovirus infections are common triggers of asthma exacerbations. Viruses can activate the inflammasome, resulting in processing and activation of caspase-1. This recruitment triggers production of interleukin (IL)-1β and IL-18, which have been implicated in asthma. Elucidating the involvement of the inflammasome and its compartments, such as caspase-1, in asthma exacerbations is warranted. Gene

Stroke is one of the leading causes of mortality and morbidity worldwide, and few therapeutic treatments have shown beneficial effect clinically. One reason for this could be the lack of risk factors incorporated into the preclinical stroke research. We have previously demonstrated phenotypic receptor changes to be one of the injurious mechanisms occurring after stroke but mostly in healthy rats.

Objective: The primary objective was to evaluate 6-month outcomes for brief and extensive automated telephony interventions targeting problematic alcohol use, in comparison to an assessment-only control group. The secondary objective was to compare levels of problematic alcohol use (hazardous, harmful or probable dependence), gender and age among study participants from clinical psychiatric and ad

The cross section of a top-quark pair produced in association with a photon is measured in proton-proton collisions at a centre-of-mass energy of s=8 TeV with 20.2 fb−1 of data collected by the ATLAS detector at the Large Hadron Collider in 2012. The measurement is performed by selecting events that contain a photon with transverse momentum pT > 15 GeV, an isolated lepton with large transverse mom