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Estimating the Global Incidence of Femoral Fracture from Road Traffic Collisions: A Literature Review.

Worldwide, road injuries cause over 1.3 million deaths and many more disabilities annually, disproportionately affecting the young and the poor. Approximately one in ten road injuries involves a femoral shaft fracture that is most effectively treated with surgery. Current femoral shaft fracture incidence according to country and age group is unknown and difficult to measure directly but is critica

The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

High hyperdiploid (51-67 chromosomes) acute lymphoblastic leukemia (ALL) is one of the most common childhood malignancies, comprising 30% of all pediatric B cell-precursor ALL. Its characteristic genetic feature is the nonrandom gain of chromosomes X, 4, 6, 10, 14, 17, 18 and 21, with individual trisomies or tetrasomies being seen in over 75% of cases, but the pathogenesis remains poorly understoo

d(13)C chemostratigraphy in the Lower-Middle Ordovician succession of Oland (Sweden) and the global significance of the MDICE

Based on the Tingskullen drillcore, we present the first continuous carbon isotope stratigraphy from the Lower-Middle Ordovician orthoceratite limestone of oland, Sweden. The extremely condensed Tremadocian and Floian stages include large gaps as well as the Ceratopyge Regressive Event and the widespread Evae transgression accompanied by prominent shifts in the C-13 record. The Dapingian and Darri

A review of air-ice chemical and physical interactions (AICI): liquids, quasi-liquids, and solids in snow

Snow in the environment acts as a host to rich chemistry and provides a matrix for physical exchange of contaminants within the ecosystem. The goal of this review is to summarise the current state of knowledge of physical processes and chemical reactivity in surface snow with relevance to polar regions. It focuses on a description of impurities in distinct compartments present in surface snow, suc

Multiparametric Flow Cytometry Profiling of Neoplastic Plasma Cells in Multiple Myeloma

Background and aim: The clinical impact of multiparametric flow cytometry (MFC) in multiple myeloma (MM) is still unclear and under evaluation. Further progress relies on multiparametric profiling of the neoplastic plasma cell (PC) compartment to provide an accurate image of the stage of differentiation. The primary aim of this study was to perform global analysis of CD expression on the PC compar

Subantarctic flowering plants: pre-glacial survivors or post-glacial immigrants?

Aim The aim here was to assess whether the present-day assemblage of subantarctic flowering plants is the result of a rapid post-Last Glacial Maximum (LGM) colonization or whether subantarctic flowering plants survived on the islands in glacial refugia throughout the LGM. Location The circumpolar subantarctic region, comprising six remote islands and island groups between latitudes 46 degrees and

Development and Use of gender-specific technologies: Evidence from China, Poland and Sweden

This article investigates the gender aspects of technology use in the innovation system. The generic question is: to what extent is it necessary to distinguish between women and men in the use of technology? A second question is: if gender-specific differences do exist, to what extent is the innovation system capable of utilizing experiences from women as well? The article examines two sets of tec

Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor.

Solitary fibrous tumor (SFT) is a mesenchymal neoplasm displaying variable morphologic and clinical features. To identify pathogenetically important genetic rearrangements, 44 SFTs were analyzed using a variety of techniques. Chromosome banding and fluorescence in situ hybridization (FISH) showed recurrent breakpoints in 12q13, clustering near the NAB2 and STAT6 genes, and single nucleotide polymo

Local and Remote Charge-Transfer-Enhanced Raman Scattering on One-Dimensional Transition-Metal Oxides

The one-dimensional (1D) transition-metal oxide MoO3 belt is synthesized and characterized with Xray diffraction, scanning electron microscopy, and Raman spectroscopy. Charge-transfer-(CT) enhanced Raman scattering of 4-mercaptobenzoic acid (4-MBA) on a 1D MoO3 belt was investigated experimentally and theoretically. The chemical enhancement of surface-enhanced Raman scattering (SERS) of 4-MBA on t

Lack of orthostatic symptoms in dementia patients with orthostatic hypotension.

Purpose: Orthostatic hypotension (OH) is common and increases with age. OH is part of the autonomic dysfunction in dementia with Lewy bodies (DLB). Commonly OH is diagnosed when the patient falls which is a risk factor of premature death. Our objective was to systematically investigate the clinical symptoms associated with measurement of OH in different neurodegenerative dementias and normal contr

Harnessing Handheld Computing – Managing IS Support to the Digital Ranger with Defensive Design

The recent years of development in mobile computing as powerful handheld computers and high-speed wireless networks creates opportunities for new user-groups in the mobile workforce to take advantage of mobile technologies. User-groups may be more or less geographical distributed and as a consequence more or less marooned when it comes to obtaining IT/IS support and this increases the complexity o

The myth of Sweden as a peace-power state and its religious motivations

Since the non-military dissolution of the political union with Norway in 1905, the myth of Sweden as a peace-power state, often with religious motivations, has been actual, and continuosly re-activated. In his ecumenical-political actions, Archbishop Nathan Söderblom was one of the most outstanding actors. Later, the political martyrdom of Count Folke Bernadotte, Dag Hammarskjöld, Raoul Wallenberg

Microbubbles as a scattering contrast agent for grating-based x-ray dark-field imaging

In clinically established-absorption-based-biomedical x-ray imaging, contrast agents with high atomic numbers (e.g. iodine) are commonly used for contrast enhancement. The development of novel x-ray contrast modalities such as phase contrast and dark-field contrast opens up the possible use of alternative contrast media in x-ray imaging. We investigate using ultrasound contrast agents, which unlik

Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry

Clinical management guidelines on malignant disorders are generally based on data from clinical trials with selected patient cohorts. In Sweden, more than 95% of all patients diagnosed with chronic myeloid leukemia (CML) are reported to the national CML registry, providing unique possibilities to compile population-based information. This report is based on registry data from 2002 to 2010, when a

Effect of tunable dot charging on photoresponse spectra of GaAs p-i-n diode with InAs quantum dots

Quantum dot (QD)-embedded photodiodes have demonstrated great potential for use as detectors. A modulation of QD charging opens intriguing possibilities for adaptive sensing with bias-tunable detector characteristics. Here, we report on a p-i-n GaAs photodiode with InAs QDs whose charging is tunable due to unintentional Be diffusion and trap-assisted tunneling of holes, from bias-and temperature (