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Cavity Field Control for Linear Particle Accelerators

High-energy linear particle accelerators enable exploration of the microscopic structure of pharmaceuticals, solar cells, fuel cells, high-temperature superconductors, and the universe itself. These accelerators accelerate charged particles using oscillating magnetic fields that are confined in metal cavities. The amplitudes and phases of the electromagnetic fields need to be accurately controlled

Circulating markers of cellular immune activation in prediagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)

Cell-mediated immune suppression may play an important role in lung carcinogenesis. We investigated the associations for circulating levels of tryptophan, kynurenine, kynurenine:tryptophan ratio (KTR), quinolinic acid (QA) and neopterin as markers of immune regulation and inflammation with lung cancer risk in 5,364 smoking-matched case–control pairs from 20 prospective cohorts included in the inte

Immune complexes in insulin-dependent diabetes

Circulating immune complexes (IC) were studied in 40 newly-diagnosed insulin-dependent diabetics (IDDM), 40 long duration IDDM, and 16 healthy controls. IC were detected by the solid-phase Clq test (SP-Clq). IDDM patients at diagnosis (25%) showed a higher incidence of IC compared to the long duration IDDM patients (15%) and the control group (7%). There was no difference in the prevalence of circ

Multiple-stressor effects on leaf litter decomposition and fungal decomposers in agricultural streams contrast between litter species

Agricultural land use commonly exerts multiple stressors on the functioning of stream ecosystems, including leaf litter decomposition and the utilization of this resource in stream food webs. If stressors interact, their cumulative effects on biotic responses cannot be predicted from knowledge of individual stressor effects, posing challenges for management and restoration of ecosystems. We examin

Compendium of Front-End Electronics

Our world is changing fast. On one hand, technological developments provide us with new and powerful electronics devices on almost a weekly basis. On the other hand, the end-user of these electronics is now rarely required to actually configure the devices, as everything is automated. This "de-empowerment" of the end-user may be detrimental to the scientific community. This is because the unique c

Late presentation of RPE65 retinopathy in three siblings

Purpose: Gene therapy for RPE65 retinopathy has been recently approved. The purpose of this study was to assess retinal structure and function in 3 siblings presenting with late-stage RPE65 retinopathy and to assess the unmet need for such therapy in Saudi Arabia. Methods: Search of the retinal dystrophy registry at King Khaled Eye Specialist Hospital and clinical examination including multimodal

Weathering rates in Swedish forest soils

Soil and water acidification was internationally recognised as a severe environmental problem in the late 1960s. The interest in establishing “critical loads” led to a peak in weathering research in the 1980s and 1990s, since base cation weathering is the long-term counterbalance to acidification pressure. Assessments of weathering rates and associated uncertainties have recently become an area of

Lipschitz continuity for weighted harmonic functions in the unit disc

We study membership in Lipschitz classes (Formula presented.) for a class of α-harmonic functions in the open unit disc (Formula presented.) in the complex plane. From earlier work by Olofsson and Wittsten we know that such an α-harmonic function u is the α-harmonic Poisson integral (Formula presented.) of its boundary value function f on the unit circle (Formula presented.). We determine when the

Contextualizing Policy : Understanding Implementation under Socio-technical Transitions

Over the past 40 years, implementation of public policy has been developed into a mature but heterogenous field of research. Despite much attention paid to the context in which implementation occurs, studies thus far has only to a limited extent been concerned with how major socio-technological transitions affect the conditions for implementing policy. As societies experience major socio-technolog

Climate science curricula in Canadian secondary schools focus on human warming, not scientific consensus, impacts or solutions

Despite an overwhelming scientific consensus that climate change poses severe risks to human and natural systems, many young Canadian adults do not view it as a major issue. We analyzed secondary science curricula in each province for their coverage of climate change according to six core topics: physical climate mechanisms (“It’s climate”), observed increase in temperature (“It’s warming”), anthr

The Power of Discretion and the Discretion of Power. Personal Assistants and Sexual Facilitation in Swedish Disability Services

AimThe purpose of this article is to explore how personal assistants, working in state-funded services for mobility-disabled people in Sweden, perceive and experience their work, with special focus on sexual facilitation (assistance with sexual activities).BackgroundPersonal assistance services are a legal right, aiming to give certain disabled people the possibility to live on equal terms in soci

Calcein release assay as a method for monitoring serum complement activity during monoclonal antibody therapy in patients with B-cell malignancies

Monoclonal antibodies ofatumumab (anti-CD20) and alemtuzumab (anti-CD52) which are approved for usage in patients with chronic lymphocytic leukemia (CLL), efficiently activate the classical complement pathway. However complement is an exhaustible component and high doses of its activators may deplete complement-dependent cytotoxicity (CDC) potential, thus reducing the effect of repeated mAb dosing

A favorable lifestyle lowers the risk of coronary artery disease consistently across strata of non-modifiable risk factors in a population-based cohort

Background: A healthy lifestyle has been shown to reduce the risk of coronary artery disease (CAD). The extent to which lifestyle influences the risk of CAD for people with pre-existing non-modifiable risk factors is less studied. We therefore examined the associations between a favorable lifestyle and incidence of CAD in population subgroups based on gender, age, educational level, and parental h

The knee control prevention programme

In 2008, the Swedish Football Association and the insurance company Folksam, where all licensed players are insured, initiated a project aiming to reduce the burden of severe knee injuries in Swedish football. As a first step, the efficacy of an injury prevention exercise programme (IPEP) was evaluated in girls’ adolescent football (12–17 years). In a large-scale cluster randomised controlled tria

"The data are irrelevant": Response to Reber & Alcock (2019)

The rebuttal by Reber and Alcock (2019a,b) to an umbrella review of multiple meta-analyses on the evidence for parapsychological (psi) phenomena (Cardeña 2018) did not engage deliberately with its data or analyses. Instead, the authors proposed that because they and some physicists consider psi phenomena to be impossible, “the data are irrelevant” (Reber & Alcock 2019b). After presenting some

Socio-spatial inequality in Tehran, a structural explanation

The study presents a political economic analysis of socio-spatial inequality in Tehran focusing on four sectors of social reproduction, namely, housing, healthcare, education, and transportation. The existing analyses of socio-spatial inequality in Tehran by Iranian social scientists see the problem as a technical matter and criticize e.g. bad planning, poor policy-making, undemocratic state, and

Marx, Marxian geography, and rent theory

The numerous interpretations of Marx’s economic theory can be usefully divided in two broad classes: real competition theory and monopolistic competition theory. Marxian geographers (inspired by Harvey) have applied the latter without discussing why they ignore the former. The problem is particularly salient when it comes to rent theory. Geographers following Harvey have famously ignored Marx’s ab

Variations of Lake Ice Phenology on the Tibetan Plateau From 2001 to 2017 Based on MODIS Data

Lake ice is a robust indicator of climate change. The availability of information contained in Moderate Resolution Imaging Spectroradiometer daily snow products from 2000 to 2017 could be greatly improved after cloud removal by gap filling. Thresholds based on open water pixel numbers are used to extract the freezeup start and breakup end dates for 58 lakes on the Tibetan Plateau (TP); 18 lakes ar