The Bogong moth (Agrotis infusa) is a small, night-active Australian moth that has a remarkable lifestyle. Afterhatching from its pupa in spring, it migrates over 1000 km to the Australian Alps, where it spends the summer incool alpine caves. In the beginning of autumn, the moths emerge from the caves and fly back to their breedinggrounds, where they mate, lay eggs, and die. The following year, a

The grasslands in arid and semi-arid regions rely heavily on the use of rain, thus, improving rain use efficiency (RUE) is essential for securing sustainable development of grassland ecosystems in these areas with limited rainfall. In this study, the spatial and temporal variabilities of RUE for grassland ecosystems over Northwestern China during 1982-2013 were analyzed using the normalized differ

PURPOSE: Dynamic glucose enhanced (DGE) MRI has shown potential for imaging glucose delivery and blood-brain barrier permeability at fields of 7T and higher. Here, we evaluated issues involved with translating d-glucose weighted chemical exchange saturation transfer (glucoCEST) experiments to the clinical field strength of 3T.METHODS: Exchange rates of the different hydroxyl proton pools and the f

Myocardin (MYOCD) is a critical regulator of smooth muscle cell (SMC) differentiation, but its transcriptional targets remain to be exhaustively characterized, especially at the protein level. Here we leveraged human RNA and protein expression data to identify novel potential MYOCD targets. Using correlation analyses we found several targets that we could confirm at the protein level, including SO

The primary aim of this thesis is to develop a theoretical model that enhances our understanding of entrepreneurial learning as a process by which personalized streams of experience become routinized and embedded in venture-wide behaviors. The aim is realized by exploring entrepreneurial learning as an experiential multilevel process. This process begins with learning at the individual level, whic

A search for a right-handed gauge boson WR, decaying into a boosted right-handed heavy neutrino NR, in the framework of Left-Right Symmetric Models is presented. It is based on data from proton–proton collisions with a centre-of-mass energy of 13 TeV collected by the ATLAS detector at the Large Hadron Collider during the years 2015, 2016 and 2017, corresponding to an integrated luminosity of 80 fb

Chronic obstructive pulmonary disease (COPD) affects the lives of an ever-growing number of people worldwide. The lack of understanding surrounding the pathophysiology of the disease and its progression has led to COPD becoming the third leading cause of death worldwide. COPD is incurable, with current treatments only addressing associated symptoms and sometimes slowing its progression, thus highl

The evolution of the widely-used PYTHIA particle physics event generator is outlined, from the early days to the current status and plans. The key decisions and the development of the major physics components are put in context.

The deep financial crisis of today has created an interest in the financial catastrophes of yesterday. LarsJonung, Research Adviser at DG ECFIN, asks: is the present crisis a rerun of those of the past?

Looking at globular proteins with the eyes of a colloid scientist has a long tradition, in fact a significant part of the early colloid literature was focused on protein solutions. However, it has also been recognized that proteins are much more complex than the typical hard sphere-like synthetic model colloids. Proteins are not perfect spheres, their interaction potentials are in general not isot

Temporal aspects of ecosystem services have gained surprisingly little attention given that ecosystem service flows are not static but change over time. We present the first systematic review to describe and establish how studies have assessed temporal patterns in supply and demand of ecosystem services. 295 studies, 2% of all studies engaging with the ecosystem service concept, considered changes

Recension av översiktsverk om dansk konst 1750-1850.

OBJECTIVES: To assess whether sevoflurane provides better haemodynamic stability than propofol in acute right ventricular (RV) ischaemia-reperfusion. METHODS: Open-chest pigs (mean ± standard deviation, 68.8 ± 4.2 kg) anaesthetized with sevoflurane (n = 6) or propofol (n = 6) underwent 60 min of RV free wall ischaemia and 150 min of reperfusion. Haemodynamic parameters and blood flow in the 3 majo

Current antipsychotic drugs are notably ineffective at addressing the cognitive deficits associated with schizophrenia. N-Desmethylclozapine (NDMC), the major metabolite of clozapine, displays muscarinic M1 receptor (M1) agonism, an activity associated with improvement in cognitive functioning. Preclinical and clinical data support that M1 agonism may be a desired activity in antipsychotic drugs.

Microdissected pancreatic islets of ob/ob mice were used to study whether glucose induced insulin release is associated with changes of the apparent extracellular space. Glucose at a concentration of 20 mM had no measurable effect on the islet uptake of sucrose and urea. In the presence of these space markers glucose stimulated insulin release significantly. The results do not invalidate the hypot