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Naumovozyma castellii: an alternative model for budding yeast molecular biology

Naumovozyma castellii (Saccharomyces castellii) is a member of the budding yeast family Saccharomycetaceae. It has been extensively used as a model organism for telomere biology research and has gained an increasing interest as a budding yeast model for functional analyses owing to its amenability to genetic modifications. Due to the suitable phylogenetic distance to S. cerevisiae the whole genome

An Okinawan-based Nordic diet improves anthropometry, metabolic control, and health-related quality of life in Scandinavian patients with type 2 diabetes : A pilot trial

Background: Our hypothesis was that a modified diet would improve blood glucose control with beneficial impact on weight management and overall health in established diabetes. Objective: This prospective interventional study investigated the clinical effect of an Okinawan-based Nordic diet on anthropometry, metabolic control, and health-related quality of life (HRQoL) in Scandinavian type 2 diabet

Asymptotics of Chebyshev polynomials, I : subsets of R

We consider Chebyshev polynomials, (Formula presented.), for infinite, compact sets (Formula presented.) (that is, the monic polynomials minimizing the (Formula presented.)-norm, (Formula presented.), on (Formula presented.)). We resolve a (Formula presented.) year old conjecture of Widom that for finite gap subsets of (Formula presented.), his conjectured asymptotics (which we call Szegő–Widom as

Early mortality and morbidity after total hip arthroplasty in patients with femoral neck fracture : A nationwide study of 24,699 cases and 118,518 matched controls

Background and purpose — Early postoperative mortality is relatively high after total hip arthroplasty (THA) that has been performed due to femoral neck fracture. However, this has rarely been investigated after adjustment for medical comorbidity and comparison with the mortality in an age-matched population. We therefore assessed early mortality in hip fracture patients treated with a THA, in the

Monoblock versus modular polyethylene insert in uncemented total knee arthroplasty : A randomized RSA study with 2-year follow-up of 53 patients

Background and purpose — Backside wear of the polyethylene insert in total knee arthroplasty (TKA) can produce clinically significant levels of polyethylene debris, which can lead to loosening of the tibial component. Loosening due to polyethylene debris could theoretically be reduced in tibial components of monoblock polyethylene design, as there is no backside wear. We investigated the effect of

Assessing risk for preclinical β-amyloid pathology with APOE, cognitive, and demographic information

Introduction Clinical trials in Alzheimer's disease are aimed at early stages of disease, including preclinical Alzheimer's disease. The high cost and time required to screen large numbers of participants for Aβ pathology impede the development of novel drugs. This study's objective was to evaluate the extent to which inexpensive and easily obtainable information can reduce the number of screen fa

Visual grading evaluation of commercially available metal artefact reduction techniques in hip prosthesis computed tomography

Objective: To evaluate metal artefact reduction (MAR) techniques from four CT vendors in hip prosthesis imaging. Methods: Bilateral hip prosthesis phantom images, obtained by using MAR algorithms for single-energy CT data or dual-energy CT (DECT) data and by monoenergetic reconstructions of DECT data, were visually graded by five radiologists using 10 image quality criteria. Comparisons between th

The "Free from housing accessibility problems" app

The present study concerns the development of a computerized tool targeting housing accessibility issues. A user-centered approach involving professionals from the housing sector and senior citizens from four European countries resulted in a fully functional prototype of a mobile application (app) including an apartment database. The app raises awareness on housing accessibility and has the potent

A Clash with the System : Experiences of teaching film and media production in the south of Sweden

As a by-product of a meeting between my university’s vice-chancellor and the manager of the largest bank in the small southern town of Ystad in 2006, I, almost accidentally, soon after came to commence teaching and researching media production, production studies, media industries studies or film and media industry studies, as the subject finally came to be called at Lund. The teaching part involv

Impact of doping and diameter on the electrical properties of GaSb nanowires

The effect of doping and diameter on the electrical properties of vapor-liquid-solid grown GaSb nanowires was characterized using long channel back-gated lateral transistors and top-gated devices. The measurements showed that increasing the doping concentration significantly increases the conductivity while reducing the control over the channel potential and shifting the threshold voltage, as expe

Play and productivity : enhancing the creative climate at workplace meetings with play cues

The authors investigate the links between playfulness and creative organizational climates established by other research, using play cues—objects and sweets—they provide participants halfway through workplace meetings. Their findings suggest such cues significantly enhance the creative climate and playfulness in workplace meetings without risking meeting productivity. Key words: adult playfulness;

Modeling subsurface deformation induced by machining of Inconel 718

Traditionally, the development and optimization of the machining process with regards to the subsurface deformation are done through experimental method which is often expensive and time consuming. This article presents the development of a finite element model based on an updated Lagrangian formulation. The numerical model is able to predict the depth of subsurface deformation induced in the high

Leadership in opera : Romance, betrayal, strife and sacrifice

What, if anything, does opera tell us about leadership, leaders and followers, that social research or indeed other art forms do not tell us? This is the question I address here. I argue that opera is a highly political genre, able to depict political events involving leaders and followers in sharply illuminating ways. In particular, through the device of the chorus it is able to represent the pol

Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence

The three-dimensional structure of a bacterial superantigen, Staphylococcus aureus enterotoxin H (SEH), bound to human major histocompatibility complex (MHC) class II (HLA-DR1) has been determined by X-ray crystallography to 2.6 Å resolution (1HXY). The superantigen binds on top of HLA-DR1 in a completely different way from earlier co-crystallized superantigens from S. aureus. SEH interacts with h

Directional interpolation of multicomponent data

A method for interpolation of multicomponent streamer data based on using the local directionality structure is presented. The derivative components are used to estimate a vector field that locally describes the direction with the least variability. Given this vector field, the interpolation can be phrased in terms of the solution of a partial differential equation that describes how energy is tra

Di-boson signatures as standard candles for partial compositeness

Composite Higgs Models are often constructed including fermionic top partners with a mass around the TeV scale, with the top partners playing the role of stabilizing the Higgs potential and enforcing partial compositeness for the top quark. A class of models of this kind can be formulated in terms of fermionic strongly coupled gauge theories. A common feature they all share is the presence of spec

Removing MOVE : A case study of intersectional invisibility within religious and legal studies

How is it that a group that self-identifies as “religious” and is associated with one of the most dramatic events in the United States during the 1980s could receive almost no attention from religious studies scholars? Furthermore, how is it that the court case in which said group was determined to not qualify as a “religion” has been discussed and challenged by legal scholars while being virtuall