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Efficacy of Lactiplantibacillus plantarum 299 and 299v against nosocomial oropharyngeal pathogens in vitro and as an oral prophylactic treatment in a randomized, controlled clinical trial

Background: Disturbance in the oropharyngeal microbiota is common in hospitalized patients and contributes to the development of nosocomial pneumonia. Lactiplantibacillus plantarum 299 and 299v (Lp299 and Lp299v) are probiotic bacteria with beneficial effects on the human microbiome. Aim: To investigate how Lp299 and Lp299v affect the growth of nosocomial oropharyngeal pathogens in vitro and to ev

Projected economic burden of pancreatic cancer in Sweden in 2030

Background: Pancreatic cancer is predicted to become the second most common cause of cancer-related death by 2030. The objective of this study was to estimate the economic burden of pancreatic cancer for the years 2018 and 2030 based on changing demographics and incidence rates in Sweden. Method: The incidence of pancreatic cancer in Sweden and additional relevant data were obtained from official

Radical Incarnation : The Dangers and Promises of Christian Universalism in the Wake of Badiou’s Saint Paul

In his 1997 pamphlet Saint Paul: The Foundation of Universalism, Alain Badiou pointed to the cynical interaction between the burgeoning identitarian movements and neoliberal capitalism. As a bulwark against these tendencies, he proposed a creative reinterpretation of Christian universalism inspired by the Pauline letters. This article revisits Badiou’s argument in light of recent debates on the li

On Vintila Mihailescu

In memorium commentary about the Romanian anthropologist Vintila Mihailescu, who died in 2020, published as part of several contributions in Anuac, the journal of the Italian Society for Cultural Anthropology

Vaginal lipidomics of women with vulvovaginal candidiasis and cytolytic vaginosis : A non-targeted LC-MS pilot study

OBJECTIVE: To characterize the lipid profile in vaginal discharge of women with vulvovaginal candidiasis, cytolytic vaginosis, or no vaginal infection or dysbiosis.DESIGN: Cross-sectional study.SETTING: Genital Infections Ambulatory, Department of Tocogynecology, University of Campinas, Campinas, São Paulo-Brazil.SAMPLE: Twenty-four women were included in this study: eight with vulvovaginal candid

Combustion chemistry of methoxymethanol. Part I : Chemical kinetics of hydrogen-abstraction reactions and the unimolecular reactions of the product [C2H5O2] radicals

The reaction kinetics of hydrogen-abstraction reactions from methoxymethanol (CH3OCH2OH) by hydrogen (Ḣ) atom, hydroxyl (ȮH), hydroperoxyl (HȮ2), methyl (ĊH3) and methoxyl (CH3Ȯ) radicals, and decomposition of the related hydroxyl-methoxyl-methyl (CH3OĊHOH), hydroxymethoxyl-methyl (ĊH2OCH2OH) and methoxyl-methoxy (CH3OCH2Ȯ) radicals, have been investigated in this study through high-level ab initi

Improvements After Arthroscopic Treatment for Femoroacetabular Impingement Syndrome in High-Level Ice Hockey Players : 2-Year Outcomes by Player Position

Background: Ice hockey players often undergo arthroscopic treatment for femoroacetabular impingement syndrome (FAIS); however, only a few studies have reported postoperative patient-reported outcomes. It has been debated whether player position is related to FAIS. Purpose: To evaluate the change in patient-reported outcome measures (PROMs) in high-level ice hockey players from presurgery to 2 year

A reliable reflection? : Challenges when documenting physical infrastructure

Minor revisions, deadline 31 januari 2021Maintaining infrastructures such as roads, bridges, railways and other civil constructions requires long term documentation that ideally should comprise a reliable reflection of the physical structures. However, the Swedish Transport Administration (TRA) states that its documentation is currently inadequate and that new working method are needed. The purpose of this paper is to study how the agenc

Zircon provenance analysis from Lower Paleocene pelagic limestones of the Bottaccione section at Gubbio (Umbria-Marche basin, Italy)

Dating detrital zircon grains from sands and sandstones has become an important geological technique for determining sediment provenance and dispersal patterns. Here, we report what we believe to be the first provenance study of zircon grains extracted by dissolving large samples of pelagic limestone. Our samples come from the Paleocene section of the Umbria-Marche Apennines, Italy. Recovery of th

Hur ska förvärv av persondata regleras?

Förvärv av persondata framställs i regel som en individuell angelägenhet för de personer vars data det handlar om. Denna inramning riktar vår uppmärksamhet mot individcentrerade rättsliga ramverk: i första hand de som skyddar den personliga integriteten, men även de som skyddar privat egendom. Detta kapitel betonar istället att storskaligt persondataförvärv ställer oss inför kollektiva problem, vi

Mitochondrial clearance of calcium facilitated by MICU2 controls insulin secretion

Objective: Transport of Ca2+ into pancreatic β cell mitochondria facilitates nutrient-mediated insulin secretion. However, the underlying mechanism is unclear. Recent establishment of the molecular identity of the mitochondrial Ca2+ uniporter (MCU) and associated proteins allows modification of mitochondrial Ca2+ transport in intact cells. We examined the consequences of deficiency of the accessor

Quantum refinement with multiple conformations : Application to the P-cluster in nitrogenase

X-ray crystallography is the main source of atomistic information on the structure of proteins. Normal crystal structures are obtained as a compromise between the X-ray scattering data and a set of empirical restraints that ensure chemically reasonable bond lengths and angles. However, such restraints are not always available or accurate for nonstandard parts of the structure, for example substrat

Low kilovoltage computed tomography to reduce contrast medium dose in patients at risk of acute kidney injury

Background: Patients with reduced renal function may be at risk of contrast medium-induced acute kidney injury (CI-AKI) following intravenous iodine contrast medium (CM) enhanced computed tomography (CT). Reducing the CM dose may reduce this risk. Decreasing the X-ray tube potential (kilovoltage, kV) from commonly used 120 to 80 kV results in higher CM attenuation due to the photoelectric properti