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Castle and Commerce in Medieval Sweden - the Examples of Stockholm, Borgholm and Piksborg.

The purpose of this paper is to highlight the connection between castles, commerce and urbanity in Scandinavia. This is made by comparing three Swedish royal castles. The castle in Stockholm has its roots in the twelfth or thirteenth century and was founded in connection with the contemporary town. Here are indications that the merchants in an early phase lived in the bailey of the castle. The casIt is generally accepted that there were well-established relationships between castles and commerce in medieval Sweden. However, to date, the complexities of those relationships have arguably not been fully explored. Through focusing on archaeological evidence from three very different examples, Stockholm, Borgholm and Piksborg, this paper seeks to illustrate the variety of often intimate and com

PEPPSI-type Complexes of Palladium and Platinum: : Investigation of Properties and Applications in Catalysis

Catalysis is a powerful tool to highly efficient production of desired newchemicals by acceleration of a chemical reaction rate. Special compounds used forthis purpose are called catalysts; they induce a change in the chemicalenvironment without being consumed during the process. Catalysis affects manyfields of life leading to a decrease of the energy use, less pollution, fewer sideproducts and loCatalysis is a powerful tool to highly efficient production of desired newchemicals by acceleration of a chemical reaction rate. Special compounds used forthis purpose are called catalysts; they induce a change in the chemicalenvironment without being consumed during the process. Catalysis affects manyfields of life leading to a decrease of the energy use, less pollution, fewer sideproducts and lo

Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer

Background: The basal-like breast cancer (BLBC) subtype is characterized by positive staining for basal mammary epithelial cytokeratin markers, lack of hormone receptor and HER2 expression, and poor prognosis with currently no approved molecularly-targeted therapies. The oncogenic signaling pathways driving basal-like tumorigenesis are not fully elucidated. Methods: One hundred sixteen unselected

Specific blood pressure targets for patients with diabetic nephropathy?

Diabetic nephropathy represents a condition frequently detected in current clinical practice characterized by a very high cardiovascular risk profile. Blood pressure reduction via antihypertension drug treatment represents a therapeutic approach capable of exerting favorable effects on renal and cardiovascular outcomes. The purpose of this article is to review the current literature and results of

Robustness of Large-Scale Stochastic Matrices to Localized Perturbations

Many notions of network centrality can be formulated in terms of invariant probability vectors of suitably defined stochastic matrices encoding the network structure. Analogously, invariant probability vectors of stochastic matrices allow one to characterize the asymptotic behavior of many linear network dynamics, e.g., arising in opinion dynamics in social networks as well as in distributed avera

Electrophysiological correlates of episodic memory retrieval are material sensitive

It remains unclear whether the event-related potential (ERP) correlates of episodic memory are modulated by the type of information retrieved. In two experiments, we recorded electrophysiological brain activity while participants discriminated between old and new items from three different stimulus categories (faces, objects, and words). In the first experiment, we used a randomized event-related

Low Cost Remote Antenna Units in CMOS for Fiber-fed Distributed MIMO Systems

Massive multiple input multiple output (MIMO) is a revolutionary communication technique, where large numbers of antennas are employed at the base stations to increase the spectral efficiency, reliability and data rate of the system. Moreover, in multi-user MIMO (MU-MIMO) multiple users can be served by the base stations on the same time-frequency resource. Distributed antenna system (DAS) is a fo

Inhibition of denitrification and oxygen utilization by Thiosphaera pantotropha

Mass spectrometry confirmed that the entire denitrification system of Thiosphaera pantotropha is present under aerobic conditions. Acetate-dependent oxygen uptake is totally inhibited by 0.3mM cyanide. Nitrate reduction by cells grown with and without nitrate was inhibited by 10 and 15mM azide, respectively. The nitrous oxide reductase was totally inhibited by 1% acetylene or 0.125mM cyanide. This

A mathematical description of the behaviour of mixed chemostat cultures of an autotrophic nitrifier and a heterotrophic nitrifier/aerobic denitrifier; a comparison with experimental data

A general, unstructured mathematical model has been used to describe the behaviour of nutrient-limited growth of two bacteria in a continuous co-culture. The experimental system consisted of a two-membered mixed culture of the heterotrophic nitrifier/aerobic denitrifier, Thiosphaera pantotropha, and the autotrophic nitrifier, Nitrosomonas europaea, competing for ammonia in chemostat culture. The o

An Adaptive Penalty Approach to Multi-Pitch Estimation

This work treats multi-pitch estimation, and in particular the common misclassification issue wherein the pitch at half of the true fundamental frequency, here referred to as a sub-octave, is chosen instead of the true pitch. Extending on current methods which use an extension of the Group LASSO for pitch estimation, this work introduces an adaptive total variation penalty, which both enforce grou

E´de´det här vi kallar kärlek? Om Alain Badious kärleksbegrepp som sanningsprocedur i en neuro-teknokratisk tidsera: exemplet adhd.

Jag avser att redogöra för sambandet, eller förhållandet, mellan formlerna 1+1=♥ och (∀a) (Ǝb) (∀c) [[(cϵa) u λ (c)] → (cϵ b)]. Då den förra formeln är hämtad från ett internetforum för personer diagnostiserade med adhd och deras anhöriga, så är den senare hämtad från den franske filosofen Alain Badious (2005a) mängdteori vari han närmar sig en ontologi om varat. Mitt eget avhandlingsprojekt rör d

3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma

Lesions of ERBB2, PTEN, and PIK3CA activate the phosphatidylinositol 3-kinase (PI3K) pathway during cancer development by increasing levels of phosphatidylinositol-3,4,5-triphosphate (PIP(3)). 3-Phosphoinositide-dependent kinase 1 (PDK1) is the first node of the PI3K signal output and is required for activation of AKT. PIP(3) recruits PDK1 and AKT to the cell membrane through interactions with the

ANIBAL, stable isotope-based quantitative proteomics by aniline and benzoic acid labeling of amino and carboxylic groups

Identification and relative quantification of hundreds to thousands of proteins within complex biological samples have become realistic with the emergence of stable isotope labeling in combination with high throughput mass spectrometry. However, all current chemical approaches target a single amino acid functionality (most often lysine or cysteine) despite the fact that addressing two or more amin