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A Case Report of a Challenging Disease : Immunoglobulin G4-Related Disease With Acute Kideny Injury

Immunoglobulin G4-related disease (IgG4-RD), which was initially identified as a type of autoimmune pancreatitis around the year 2000, is now widely acknowledged to be a systemic sickness. Based on both general and organ-specific criteria, alongside laboratory measurements of IgG4-subtype, the diagnosis is made. The diagnosis requires, however, a heightened index of suspicion, especially given the

Numerical and experimental investigations on residual stress evolution of multiple sequential cuts in turning

Residual stress is of great importance on the fatigue life of components; nevertheless, most of the simulations of turning operation focus on the first cut and ignore the evolution of residual stress in sequential cutting. The present study aims to explore the surface residual stress profile along the feed direction during longitudinal turning, to understand the impact of sequential cuts on turnin

Decolonising pedagogy in practice : cuerpo-territorio to consolidate students´ learning

Cuerpo-territorio is a method stemming from Latin American geography, which recognizes the centrality of situated and embodied experiences as a form of knowing. We engaged with this method in the classroom to understand how students through their embodied and situated experiences had absorbed a post-development geographic course content and how these notions had remained with them. Given that emot

Quantum and Approximation Algorithms for Maximum Witnesses of Boolean Matrix Products

The problem of finding maximum (or minimum) witnesses of the Boolean product of two Boolean matrices (MW for short) has a number of important applications, in particular the all-pairs lowest common ancestor (LCA) problem in directed acyclic graphs (dags). The best known upper time-bound on the MW problem for n × n Boolean matrices of the form O(n2.575) has not been substantially improved since 200

Seed treatment with clothianidin induces changes in plant metabolism and alters pollinator foraging preferences

Neonicotinoids, systemic insecticides that are distributed into all plant tissues and protect against pests, have become a common part of crop production, but can unintentionally also affect non-target organisms, including pollinators. Such effects can be direct effects from insecticide exposure, but neonicotinoids can affect plant physiology, and effects could therefore also be indirectly mediate

RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine

Aims/hypothesis: Roux-en-Y gastric bypass surgery (RYGB) frequently results in remission of type 2 diabetes as well as exaggerated secretion of glucagon-like peptide-1 (GLP-1). Here, we assessed RYGB-induced transcriptomic alterations in the small intestine and investigated how they were related to the regulation of GLP-1 production and secretion in vitro and in vivo. Methods: Human jejunal sample

Hybrid Governance Arrangements for Urban Infrastructure Transitions : Comparing the Adoption of Onsite Water Reuse in San Francisco and New York City

Decentralized water reuse technologies are increasingly being explored as a transformative approach for complementing centralized water and wastewater infrastructure. A transition to onsite water reuse requires a better understanding of how urban infrastructures are governed. While governance tends to be discussed within ideal types─i.e., hierarchy, market, and network─researchers increasingly rec

Gene Duplication, Shifting Selection, and Dosage Balance of Silicon Transporter Proteins in Marine and Freshwater Diatoms

Numerous factors shape the evolution of protein-coding genes, including shifts in the strength or type of selection followinggene duplications or changes in the environment. Diatoms and other silicifying organisms use a family of silicon transporters(SITs) to import dissolved silicon from the environment. Freshwaters contain higher silicon levels than oceans, and marinediatoms have more efficient

From state-controlled to free migration : The income effects of the 2008 Swedish labour-migration reform

In 2008, Sweden changed its labour-migration policy to facilitate more labour migration from countries outside the EU. Most state ambitions to shape labour migration, including practices such as the use of labour-market tests and the assessment of migrants' human capital, were abandoned and the responsibility to select migrants was transferred to employers. We use Swedish register data and adopt a

Optimal Carrier Frequency Design for Frequency Diverse Array Mimo Radar

In this work, we introduce a novel approach for designing the transmit frequency offset scheme based on Cramér-Rao lower bound (CRLB) minimization for a frequency diverse array multiple-input multiple-output (FDA-MIMO) radar. The problem originates in non-uniform FDA radar where each frequency offset scheme derives from a specific mathematical model, but where no optimization is conducted with res

Co-creating holistic injury prevention training for youth handball: Development of an intervention targeting end-users at the individual, team, and organizational levels.

BackgroundInterventions that are co-created with end-users, and that are informed by behavior change or implementation theories, support implementation in real world settings. However, injury prevention programs for youth athletes have typically been developed by experts with no, or insufficiently described, end-user involvement and without guidance by theories. The aim of the current study was to

Machine Learning Models for Prediction of Diabetic Microvascular Complications

IMPORTANCE AND AIMS: Diabetic microvascular complications significantly impact morbidity and mortality. This review focuses on machine learning/artificial intelligence (ML/AI) in predicting diabetic retinopathy (DR), diabetic kidney disease (DKD), and diabetic neuropathy (DN).METHODS: A comprehensive PubMed search from 1990 to 2023 identified studies on ML/AI models for diabetic microvascular comp