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Ataxia-telangiectasia kartlagd i Sverige

Ataxia-telangiectasia (AT) is a rare autosomal recessive disease with a complex phenotype involving cerebellar degeneration, immunodeficiency, cancer risk and radiosensitivity. Our aim has been to identify Swedish AT patients in order to study the possible "Swedish phenotype" of the disease. In the 19 patients identified in Sweden we found a phenotype fairly similar to what has been described inte

Carotenoid and pheophytin on semiconductor surface: Self-assembly and photoinduced electron transfer

Self-assembling of a carotenoid and pheophytin a into a supramolecular system was observed on the surface of nanocrystalline TiO2, and the photoinduced electron-transfer reactions within the system were studied by means of femtosecond transient absorption and laser flash photolysis techniques. Excitation of the pheophytin moiety results in ultrafast electron transfer from carotenoid to the excited

User's guide to OSFIC. A computer program for oilspill fires in compartments

This document is a description of the computer code OSFIC. The development of the code was sponsored by the Swedish Nuclear Power Inspectorate as an effort to develop useful tools for fire analyses in nuclear power plants. The name OSFIC stands for "OilSpill Fires In Compartments". The purpose of this paper is to describe the code and to facilitate the use of the computer program. A more detailed

Skadliga ljud

Foreword to texts by Stig Arlinger: Hörselskador - hur uppstår de och hur kan man förebygga?, Kim Kähäri: Akustikprojektet i Göteborg, Per Hiselius: Objekt i öronen - möjligheter och faror

Wedding Ceremonies in Punjab

While the specificities of different religious communities are underscored, the paper focuses on the shared cultural values and symbols that frame marriage ceremonies in the Punjab. The study concludes with how ritual theories help us analyse these ceremonies and assess the impact of modernity on their nature and function.

Review of Religion and Friendly Fire

This is a review (5 pages) of D.Z. Phillips' book "Religion and Friendly Fire. Examining Assumptions in Contemporary Philosohpy of Religion", Aldershot: Ashgate, 2004, written by request from Ars Disputandi.

Fetal ECG waveform analysis

Fetal ECG waveform analysis as an adjunct to electronic fetal monitoring (EFM) has developed over the last 3 decades. From a multitude of potential parameters, ST waveform analysis has been documented to provide the information required to shift EFM from a screening device to a diagnostic tool that meets the standards of evidence-based medicine. This chapter details the experimental and clinical e

Life after stroke Outcome and views of patients and carers

Popular Abstract in Swedish Det finns i Sverige idag över 100 000 personer vilka överlevt insjuknande i stroke (blodpropp eller blödning i hjärnan). Varje år inträffar ca 20 000 ? 25 000 nyinsjuknanden och ca 5 000 - 10 000 återinsjuknanden i stroke. Vanliga symtom både vid det akuta insjuknandet, och senare efter genomgången akutsjukvård och rehabilite-ring, är förlamningar, talrubbningar, sväljnThe aims were to follow stroke patients over time with respect to general pain, shoulder pain, weight loss, and health related quality of life (HRQOL), the latter also in stroke survivors' informal caregivers. Methods During a 1 year period, 416 first-ever stroke patients were included in the population based Lund Stroke Register; 327 survivors were followed up after four months and 305 one year

Necked-in Superdeformed Nuclei

Superdeformation, i.e. elongated shapes with the longest axis approximately twice as long as the shorter axes, has provided many new insights in nuclear structure. In this dissertation the possibility of forming superdeformed states related to two connected spheres, having a more or less pronounced neck, is investigated. Detailed Nilsson-Strutinsky calculations with the cranked Woods-Saxon potenti

Abnormal Ca2+-calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental parkinsonism

The NMDA receptor complex represents a key molecular element in the pathogenesis of long-term synaptic changes and motor abnormalities in Parkinson's disease (PD). Here we show that NMDA receptor 1 (NR1) subunit and postsynaptic density (PSD)-95 protein levels are selectively reduced in the PSD of dopamine (DA)-denervated striata. These effects are accompanied by an increase in striatal levels of

Development of an oat-based sour milk-like product

A fermented, oat-based product with properties resembling those of the traditional, Swedish, fermented milk product "filmjoelk" (sour milk) was developed. Com., mixed-strain, mesophilic starter cultures were grown in the oatbases M30, G40, and Oatly, which differed in the compn. of their carbohydrates. The exopolysaccharide-producer Pediococcus damnosus 2.6 was included to increase the viscosity o

Resonant soft X-ray emission spectroscopy of doped and undoped vanadium oxides

Resonant soft X-ray emission (RSXE) spectra of NaV2O5, MoxV1-xO2 and V2O3 have been recorded for a series of excitation energies at resonances of the V L- and O K-absorption band. Resonant excitation allows us, firstly, to separate V 3d and O 2p projected density-of-states of the valence band and, secondly, to study charge-neutral low-energy excitations due to resonant inelastic X-ray scattering (

Infusion of prostacyclin following experimental brain injury in the rat reduces cortical lesion volume

Endothelial-derived prostacyclin is an important regulator of microvascular function, and its main actions are inhibition of platelet/leukocyte aggregation and adhesion, and vasodilation. Disturbances in endothelial integrity following traumatic brain injury (TBI) may result in insufficient prostacyclin production and participate in the pathophysiological sequelae of brain injury. The objective of

Comprehensive regional and temporal gene expression profiling of the rat brain during the first 24 h after experimental stroke identifies dynamic ischemia-induced gene expression patterns, and reveals a biphasic activation of genes in surviving tissue

In order to identify biological processes relevant for cell death and survival in the brain following stroke, the postischemic brain transcriptome was studied by a large-scale cDNA array analysis of three peri-infarct brain regions at eight time points during the first 24 h of reperfusion following middle cerebral artery occlusion in the rat. K-means cluster analysis revealed two distinct biphasic

Effects of bile diversion in rats on intestinal sphingomyelinases and ceramidase.

Alkaline sphingomyelinase (Alk-SMase) and neutral ceramidase (N-CDase) in the intestinal microvillar membrane are responsible for dietary sphingomyelin digestion. The activities of the enzymes require the presence of bile salt, and the enzymes can be released into the gut lumen in active forms by bile salts and trypsin. It is unclear to what extent that the intestinal presence of bile salts is cri