A craniopharyngioma (CP) is an embryonic malformation of the sellar and parasellar region. The annual incidence is 0.5-2.0 cases/million per year and approximately 60% of CP is seen in adulthood. The therapy of choice is surgery, followed by cranial radiotherapy in about half of the patients. Typical initial manifestations at diagnosis in children are symptoms of elevated intracranial pressure, vi

Endocrine-disrupting compounds are exogenous agents that interfere with the natural hormones of the body. Human biological monitoring is a powerful method for monitoring exposure to endocrine disrupting compounds. In this review, we describe human biological monitoring systems for different groups of endocrine disrupting compounds, polychlorinated biphenyls, brominated flame retardants, phthalates

Bipolar disorder (BD) is a severe illness that has a serious impact on the lives of those affected and on their families. The aim of this study was to elucidate what it means for family members to live with an adult person who has BD, with reference to their views concerning the condition of the person affected and the future. During 2005, 17 family members of people with the disorder were intervi

Introduction: Airway remodelling refers to a wide pattern of patophysiological mechanisms involving smooth muscle cell hyperplasia, increase of activated fibroblasts and myofibroblasts with deposition of extracellular matrix. In asthma, it includes alterations of the epithelial cell layer with goblet cell hyperplasia, thickening of basement membranes, peri-bronchial and peri-broncheolar fibrosis.

Amino-functional benzoxazine monomers have been successfully prepared. Several routes have been applied to incorporate amino group into benzoxazine structure. These approaches include reduction of the corresponding nitro-functional benzoxazines and deprotection of protected amino-functional benzoxazine monomers. Various approaches that allow primary amine groups to be prepared without damaging the

Several ceramic biomaterials have been suggested as promising alternatives to autologous bone to replace or restore bone after trauma or disease. The osteoinductive potential of most scaffolds is often rather low by themselves and for this reason growth factors or drugs have been supplemented to these synthetic materials. Although some growth factors show good osteoinductive potential their drawba

Background: The aim of this study was to evaluate the day-care interventions implemented in southern Sweden to restrict the dispersion of penicillin-non-susceptible pneumococci with a minimum inhibitory concentration of penicillin G of at least 0.5 mg/l (PNSP0.5). Methods: A retrospective epidemiological study was performed and data from 109 day-care centre interventions from 2000 to 2010 were ana

Between 2008 and 2010, Lund University took part in three international benchmarking projects, E-xcellence+, the eLearning Benchmarking Exercise 2009, and the First Dual-Mode Distance Learning Benchmarking Club. A comparison of these models revealed a rather high level of correspondence. From this finding and from desktop studies of the current discourse regarding e-learning, a conceptual framewor

A new curriculum is planned for the medical school at Lund University, Sweden. Pharmacology, in a broad sense, has been identified as a subject that needs to be strengthened based on needs in the healthcare system. The aim was to identify the competencies in basic and clinical pharmacology that a newly qualified physician needs. Using a modified three-round Delphi technique, 31 physicians were inv

Over the past 40 years, tourism has developed to become a sector of global economic, social and environmental significance. This paper provides a retrospective overview of the massive expansion and evolving geography of international and domestic tourism over the last 40 years, including the factors that enabled and challenged this growth, in order to contextualize a discussion of what the next 40

In 1977 van Fraassen showed convincingly, and in detail, how one can give a dissentive answer to the question “[a]re there necessities in nature?”. In this paper, I follow his lead and show in a similar fashion and detail, how it is 5 possible to give a dissentive answer to: Are there probabilities in nature? This is achieved by giving a partial analysis – with the aid of Kaplanian pragmatics – of

Abstract Objective. Aerobic fitness, defined as maximum oxygen uptake (VO(2PEAK)), and body fat measurements represent two known risk factors for disease. The purpose of this study was to investigate the relationship between VO(2PEAK) and body fat measurements in young children at a population-based level. Methods. Cross-sectional study of 225 children (128 boys and 97 girls) aged 8-11 years, recr

The first appearance datum (FAD) of the cosmopolitan agnostoid trilobite Lotagnostus americanus is a widely used marker for defining the base of the uppermost stage of the Cambrian System. Detailed field study on the L. americanus-bearing interval of the Wa'ergang section, Hunan, China, reveals the FAD of L. americanus to be 29.65m above the base of the Shengjiawan Formation. This horizon is close

2-(1-Naphthyl)-pyridine () possesses sp(2) C-H bonds in both the γ- and δ-positions and is therefore a suitable substrate for studying the cyclometallation selectivity with different reagents and conditions. Such selectivity studies are reported. Based on deuterium-exchange experiments it is concluded that cycloruthenation with RuCl2(p-cymene) dimer is reversible with kinetic and thermodynamic pre

We studied the solubilization of oil in the C16E8/hexadecane/H2O system. Close to the phase inversion temperature (PIT), the system, at equilibrium, can form either homogeneous states (i.e., microemulsions) at high surfactant concentrations or three-phase states at lower concentrations. We show that, under gentle shear, at a line we named the clearing boundary (CB), located a few degrees below the

This work treats multi-pitch estimation, and in particular the common misclassification issue wherein the pitch at half the true fundamental frequency, the sub-octave, is chosen instead of the true pitch. Extending on current group LASSO-based methods for pitch estimation, this work introduces an adaptive total variation penalty, which enforces both group- and block sparsity, as well as deals with