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Differential neurochemical properties of central serotonergic transmission in Roman high- and low-avoidance rats

The selective breeding of Roman high- (RHA/Verh) and low-avoidance (RLA/Verh) rats for rapid versus poor acquisition of active avoidant behaviour has produced two behavioural phenotypes with different performances in a variety of animal models of anxiety, in which RLA/Verh rats are consistently more fearful than RHA/Verh rats. In addition, these two lines display different functional properties of

The Munich Fission Fragment Accelerator

For the new Munich high-flux reactor FRM-II a fission fragment accelerator is under design. The accelerator will deliver intense mass-separated beams of very neutron-rich fission fragments with energies at and beyond the Coulomb barrier. One main physics goal will be the investigation of very heavy neutron-rich nuclei produced in fusion reactions.

Lower limb lymphedema: Experiences and perceptions of cancer patients in the late palliative stage

Lower limb lymphedema (LLL) is a common but neglected problem in palliative cancer patients. No studies have focused on these patients' experiences of lymphedema. The aims of this study were to explore patients' experiences regarding LLL and how they manage to deal with this in the late palliative stage. Methods: Thirteen patients with cancer-related LLL were included to satisfy a maximum variatio

Modeling multicylinder paper drying - Validation of a new simulation program

A mathematical model was developed for the drying of paper in a multi-cylinder drying section. The model is based on the unsteady state, one-dimensional heat conduction equation, which is applied to both the cylinder shell and the paper web. No internal mass transfer phenomena were modeled explicitly. Great emphasis ws placed on finding the proper heat and mass transfer coefficients that are integ

Fartygsolyckor i Öresund - människan, människa-teknik-systemet och organisationen som risk- och säkerhetsfaktorer

Denna rapport är författad inom pilotprojektet ”Maritima risker i Öresundsområdet” (Sundrisk) där projektets avsikt var att genomföra en integrerad riskanalys av maritima risker i Öresundsområdet. En serie rapporter från olika discipliner har författats inom pilotprojektet. Målsättningen med delprojektet som presenteras i denna rapport var att identifiera och belysa brister i organisation och män

Neuronal loss in the brainstem and cerebellum--part of the normal aging process? A morphometric study of the vermis cerebelli and inferior olivary nucleus

Based on the known age-related loss of Purkinje cells (PC) in the cerebellum, this study focuses on whether a marked loss of PC occurs in individuals of very high age. The inferior olive, which is intimately connected with the cerebellum anatomically as well as functionally, was also studied. The study group included 15 nondemented and basically healthy cases aged 32-104 years. Linear neuronal den

On chip integrated sample preparation for proteomics

Popular Abstract in Swedish Internationellt satsas det inom bioteknologin för närvarande miljardbelopp på utveckling av mikrosystem för avancerad genom- och proteomikforskning. Genomet avser den uppsättning arvsanlag som varje individ har i varje enskild cell och proteomet är den mängd proteiner som finns i varje organism (cell). Den mängd information som döljer sig i genomet och proteomet förThe aim of this thesis project has been to create miniaturized analytical tools that improve sample preparation for the very rapidly growing field of proteomics research. The presented miniaturized analytical tools provide novel and generic analytical solutions, which are highly adaptable for analysis of various low abundant biomolecules. The adaptability and generality of the analytical technolog

Superoxide as an obligatory, catalytic intermediate in photosynthetic reduction of oxygen by adrenaline and dopamine.

The superoxide anion radical is known to be the first product of photosynthetic reduction of oxygen mediated by a variety of electron carriers. The effectiveness of many of these electron carriers as herbicides, and the toxicity of the superoxide they produce, have been suggested to rule out oxygen reduction as a physiological component of normal photosynthesis. Here results with isolated spinach

Point processes of exits by bivariate Gaussian processes and extremal theory for the chi^2-process and its concomitants

Let ζ(t), η(t) be continuously differentiable Gaussian processes with mean zero, unit variance, and common covariance function r(t), and such that ζ(t) and η(t) are independent for all t, and consider the movements of a particle with time-varying coordinates (ζ(t), η(t)). The time and location of the exists of the particle across a circle with radius u defines a point process in R3 with its points

An estimate of the worldwide prevalence and disability associated with osteoporotic fractures

Objective The aim of this study was to quantify the global burden of osteoporotic fracture worldwide. Methods The incidence of hip fractures was identified by systematic review and the incidence of osteoporotic fractures was imputed from the incidence of hip fractures in different regions of the world. Excess mortality and disability weights used age- and sex-specific data from Sweden to calculate

Identification and synthesis of new bicyclic acetals from caddisflies (Trichoptera)

As shown by synthesis and enantioselective gas chromatography, males and females of the caddisfly species Potamophylax latipennis and Potamophylax cingulatus produce (1R,3S,5S,7S)-1-ethyl-3,5,7-trimethyl-2,8-dioxabicyclo[3.2.1]octane, while Glyphotaelius pellucidus produces 1,3-diethyl-4,6-dimethyl-2,7-dioxabicyclo[2.2.1]heptane, having either the (1S,3S,4R,6S) or (1R,3R,4S,6S)-configuration. As s

High resolution polarization spectroscopy and laser induced fluorescence of CO2 around 2 mu m

High resolution Infrared Polarisation Spectroscopy (IRPS) and Infrared Laser Induced Fluorescence (IRLIF) techniques were used to probe CO2/N-2 binary gas mixture at atmospheric pressure and ambient temperature. The probed CO2 molecules were prepared by laser excitation to an overtone and combination ro-vibrational state (12(0)1, J = 15) of CO2, centred at 4988.6612 cm(-1). IRPS and IRLIF line pro

Cost-effective treatment of uncomplicated gonorrhoea including co-infection with Chlamydia trachomatis

We evaluated the cost effectiveness of treating uncomplicated gonorrhoea in a theoretical cohort of 1000 adults (nonpregnant women of reproductive age, or men) with either intramuscular ceftriaxone 125 mg or a single oral dose of cefixime 400 mg, ofloxacin 400 mg or ciprofloxacin 500 mg. We assumed that all patients were also empirically treated for uncomplicated chlamydial infection, with either