We have studied drug release and skin permeation from several different liquid crystalline lipid formulations that may be used to control the respective release rates. We have studied the release and permeation through human skin of a water-soluble and amphiphilic drug, propranolol hydrochloride, from several formulations prepared with monoolein and phytantriol as permeation enhancers and controll

Aim: To study if age and non-behavioural measures of biological maturity have any associations with attention deficit hyperactivity disorder (ADHD). Methods: Two hundred fifty-one children 7 to 9 years of age in a Swedish school were screened for ADHD-symptom. ADHD-symptoms were estimated by Conners Abbreviated Questionnaire by both parents and teachers. Motor function, body weight and body height

Abstract in UndeterminedThe radio channels between nodes of an indoor peer-to-peer network show specific fast fading characteristics. Depending on the mobility and on the scattering properties of the environment, different kinds of fading distributions can occur: Ricean fading between static nodes, but also Rayleigh or even double-Rayleigh fading between mobile nodes. We investigate fast fading in

While histopathology of excised tissue remains the gold standard for diagnosis, several new, non-invasive diagnostic techniques are being developed. They rely on physical and biochemical changes that precede and mirror malignant change within tissue. The basic principle involves simple optical techniques of tissue interrogation. Their accuracy, expressed as sensitivity and specificity, are reporte

This article is a reflection on the changing landscape of academic history in recent decades and it captures shifts in this landscape. The points made are several. Firstly, postmodernism - or rather the linguistic and cultural turn - does not represent a break with the traditional paradigm of history, although it has challenged and annoyed several historians. Neither is it a temporary fashion. Ins

The active site of the [FeFe] hydrogenases contains two Fe ions bound to one Cys ligand, three CO molecules, two CN(-) ions, and a dithiolate ligand. The nature of the last of these has been much discussed, and it has been suggested that it contains C, N, or O as the bridgehead atom. Most experimental studies indicate a N atom, whereas a recent density functional theory (DFT) study of a crystal st

Adolescent health is regarded as central to global health goals. Investments made in adolescent health and health services protect the improvements witnessed in child health. Though Saudi Arabia has a large adolescent population, adolescent health-care only began to emerge in recent years, yet widespread uptake has been very limited. Health-care providers are key in addressing and providing the ne

Asteroseismology has the capability of precisely determining stellar properties that would otherwise be inaccessible, such as radii, masses, and thus ages of stars. When coupling this information with classical determinations of stellar parameters, such as metallicities, effective temperatures, and angular diameters, powerful new diagnostics for Galactic studies can be obtained. The ongoing Stromg

We have performed the first measurement of the coherent psi(2S) photo-production cross section in ultraperipheral Pb-Pb collisions at the LHC. This charmonium excited state is reconstructed via the psi(2S) -> l(+)l(-) and ->(2S) -> J/psi pi(+)pi(-) decays, where the J/psi decays into two leptons. The analysis is based on an event sample corresponding to an integrated luminosity of about 22 mu b(-1

Klass är i ropet igen. I kulturtidskrifter pågår intensiva diskussioner om begreppet. I denna text föreslår jag att vi borde analysera hur klass konstrueras i olika sammanhang för att förstå konstruktionens betydelse för nuet och den historiska utvecklingen.

Increasing precipitation and surface water temperature due to global change may strengthen the salinity gradient in coastal regions, which could influence the behaviour of dinoflagellate migration. We studied diel vertical migration (DVM) behaviour in the dinoflagellates Prorocentrum minimum and Heterocapsa triquetra using vertically stratified laboratory columns with 3 different salinity gradient

The four proton-hole nucleus Pt-204 was populated in the fragmentation of an E/A = 1 GeV Pb-208 beam. The yrast structure of Pt-204 has been observed up to angular momentum I = 10h by detecting delayed gamma-ray transitions originating from metastable states. These long-lived excited states have been identified to have spin-parities of I-pi = (10(+)), (7(-)), and (5(-)) and half-lives of T-1/2 = 1

The central nervous system (CNS) monitors modifications in metabolic parameters or hormone levels and elicits adaptive responses such as food intake regulation. Particularly, within the hypothalamus, leptin modulates the activity of pro-opiomelanocortin (POMC) neurons which are critical regulators of energy balance. Consistent with a pivotal role of the melanocortin system in the control of energy

The article presents and discusses a number of recent scholarly attempts to investigate theological and/or religious dimensions of music. On the basis of critical interpretations of these (Anglophone and German) contributions the article proposes an interdisciplinary approach to a theological aesthetics of music. Such a methodology necessitates any "theologizing" to respect the singular qualities

The transport behavior of lambda-DNA (48 kbp) in fused silica nanoslits is investigated upon application of electrical fields of different strengths. The slit dimensions are 20 nm in height, 3 microm in width, and 500 microm in length. With fields of 30 kV/m or below, the molecules move fluently through the slits, while at higher electrical fields, the DNA molecules move intermittently, resulting

Heparin-induced thrombocytopenia (HIT, type II) is an immune-mediated disorder due to antibodies formed against heparin platelet factor 4 complexes, usually appearing at days 5 to 14 after initiation of heparin. It is important to recognize HIT because heparin prophylaxis or treatment paradoxically associates with new venous and/or arterial thrombosis. Early clinical suspicion and diagnosis togeth

We present results on fabrication and de characterization of vertical InAs nanowire wrap-gate field-effect transistor arrays with a gate length of 50 nm. The wrap gate is defined by evaporation of 50-nm Cr onto a 10-nm-thick HfO2 gate dielectric, where the gate is also separated from the source contact with a 100-nm SiOx spacer layer. For a drain voltage of 0.5 V, we observe a normalized transcond