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Trophism, tropism, and specificity in nerve regeneration

Target-derived neurotrophic factors are of basic importance for survival of neurons. In the normal state, such neurotrophic factors, synthesized by the target tissues, are taken up by nerve terminals and transported by retrograde axonal transport in axons to the nerve-cell bodies to maintain their viability. After nerve injury, neurotrophic factors are synthesized by non-neuronal cells (Schwann ce

The effects of delayed nerve repair on nerve regeneration in a silicone chamber model

The silicone chamber model for nerve regeneration is suitable to test the effects of exogenous agents or surgical manipulations on nerve regeneration. The total 16-day regeneration period used in this model makes it possible to analyze the effects of certain manipulations on the sequential advancement of the individual cellular components (circumferential perineurial-like cells, vessels, Schwann c

Experimental hyperthyroidism stimulates axonal growth in mesothelial chambers

An experimental model is presented for studying axonal growth after experimental hyperthyroidism and hypothyroidism. The left sciatic nerve of the rat was transected and transposed to the back. The proximal nerve stump was inserted into a 50-mm-long mesothelial chamber leaving the distal end of the chamber open. Different groups of young adult rats were given daily injections of thyroxine (10 micr

Mechanical effects of compression of peripheral nerves

Effects of graded compression on nerve function were analyzed in order to evaluate the relative importance of pressure level and duration of compression for functional deterioration. The pressure was applied by means of a small inflatable cuff. The effects of two pressure levels, i.e., 80 mm Hg applied for 2 hr or 400 mm Hg applied for 15 min, were studied in rabbit tibial nerves. The lower pressu

Nerve repair and axonal transport. Distribution of axonally transported proteins during maturation period in regenerating rabbit hypoglossal nerve

The distribution of fast migrating [3H]leucine-labelled proteins was studied in transected and repaired rabbit hypoglossal nerves. The nerves were repaired 90 days earlier with mesothelial chamber or epineurial suture technique. Fast migrating radiolabelled proteins were transported into the distal nerve segment and neurophysiological recordings from the tongue as well as the presence of myelinate

Microvascular effects of chondroitinase ABC and chymopapain. An in vivo experimental study on hamsters and rabbits

Immediate and long-term microvascular effects of chondroitinase ABC, 200 unit/ml, were analyzed in ten hamsters. The immediate effects on the microcirculation were studied by vital microscopy following local injection in the cheek pouch. There were no detectable effects on the microvascular blood flow during the 60 minutes of observation for chondroitinase ABC or the control. A therapeutic concent

Sonogashira cross-coupling over Au(1 1 1): from UHV to ambient pressure

We have studied the reaction of phenylacetylene (PA) with chloro-, bromo-, and iodobenzene on the Au(1 1 1) surface as a model system for the gold-catalysed Sonogashira cross-coupling. Both ultrahigh vacuum-based and ambient pressure x-ray photoelectron spectroscopy show that iodo- and chlorobenzene (IB and CB) undergo the cross-coupling reaction towards diphenylacetylene. Bromobenzene (BB), in co

Transforming Indonesia: Structural change in a regional perspective, 1968-2010

Since 1968, Indonesia has been among the few developing countries able to sustain per capita income growth over 5%. However, poverty and surplus labor are still main features of the economy. We ask to what extent the dual nature of growth has stimulated structural change, or just rewarded a particular sector or region. We find that the emblematic State support to agriculture has not untapped the p

Exploration of Electro-Enhanced-Chemotherapy I : Exploration of the uptake of radioactive tracer in rat Muscle tissue of 2 - 12 applied electric pulses of 600;800;1000;1200 V/cm field-strength, 100;250;500 s pulse-length, and 2,4,6,8.10.12 number.

Syftet med studien är att undersöka den förbättrade upptagningen av det radioaktiva spåret Technetium-99m-DTPA (99mTc-DTPA) i råtta Muskelvävnad i Fischer 344 råttor efter applicerade elektriska pulser av olikafältstyrka och pulslängd,Metoder: 99mTc-DTPA (totalt 150 MBq) administrerades intramuskulärt (i.m.) vid axelnsom en bolus i flera fraktioner om 50 l var och en i intervaller på 1 minut. Bil

Performance of the ATLAS track reconstruction algorithms in dense environments in LHC Run 2

With the increase in energy of the Large Hadron Collider to a centre-of-mass energy of 13 TeV for Run 2, events with dense environments, such as in the cores of high-energy jets, became a focus for new physics searches as well as measurements of the Standard Model. These environments are characterized by charged-particle separations of the order of the tracking detectors sensor granularity. Basic

On electric resistance effects of non-homogeneous GDL deformation in a PEM fuel cell

The electric resistance is very important for the performance of a proton exchange membrane (PEM) fuel cell. However, the performance analysis is more complex as the cell operates under assembly conditions. At such conditions, the mass transfer is deteriorated but the electric conductivity is favored. In this paper, the electric resistance of a cell is evaluated by application of a recently develo

Heat treatment of low-alloyed steel up to grade Q125

This work investigates the problem of how to reduce the prime cost of Grade Q125 Group 4 casing and tubing according to API 5CT and proposes process solutions to resolve it, consisting in the enhancement of series of mechanical properties without chemical alloying of steel with expensive elements such as chromium, molybdenum, vanadium, niobium and boron. During the investigation the process parame

Subgroup analyses of the effectiveness of oral glucosamine for knee and hip osteoarthritis : A systematic review and individual patient data meta-Analysis from the OA trial bank

Objective To evaluate the effectiveness of oral glucosamine in subgroups of people with hip or knee osteoarthritis (OA) based on baseline pain severity, body mass index (BMI), sex, structural abnormalities and presence of inflammation using individual patient data. Methods After a systematic search of the literature and clinical trial registries, all randomised controlled trials (RCTs) evaluating

A Glucose/Oxygen Enzymatic Fuel Cell based on Gold Nanoparticles modified Graphene Screen-Printed Electrode. Proof-of-Concept in Human Saliva

This paper presents a new direct electron transfer based-miniaturized glucose/oxygen enzymatic fuel cell (EFC) whose operating ability has been tested in real saliva samples. The bioanode and biocathode are a graphene working electrode and a graphite counter electrode localized on the same screen printed electrode (SPE) modified with poly(vinyl alcohol) N-methyl-4(4'-formylstyryl)pyridinium methos