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Fluid evolution in CM carbonaceous chondrites tracked through the oxygen isotopic compositions of carbonates

The oxygen isotopic compositions of calcite grains in four CM carbonaceous chondrites have been determined by NanoSIMS, and results reveal that aqueous solutions evolved in a similar manner between parent body regions with different intensities of aqueous alteration. Two types of calcite were identified in Murchison, Mighei, Cold Bokkeveld and LaPaz Icefield 031166 by differences in their petrogra

The paradox between low shock-stage and evidence for compaction in CM carbonaceous chondrites explained by multiple low-intensity impacts

Petrographic analysis of eight CM carbonaceous chondrites (EET 96029, LAP 031166, LON 94101, MET 01072, Murchison, Murray, SCO 06043, QUE 93005) by electron imaging and diffraction, and X-ray computed tomography, reveals that six of them have a petrofabric defined by shock flattened chondrules. With the exception of Murchison, those CMs that have a strong petrofabric also contain open or mineraliz

Evidence for an impact-induced biosphere from the δ34S signature of sulphides in the Rochechouart impact structure, France

The highly eroded 23 km diameter Rochechouart impact structure, France, has extensive evidence for post-impact hydrothermal alteration and sulphide mineralisation. The sulphides can be divided into four types on the basis of their mineralogy and host rock. They range from pyrites and chalcopyrite in the underlying coherent crystalline basement to pyrites hosted in the impactites. Sulphur isotopic

Kinetics and mechanism of oxidation of the anti-tubercular prodrug isoniazid and its analog by iridium(IV) as models for biological redox systems

A complex reaction mechanism of oxidation of the anti-tubercular prodrug isoniazid (isonicotinic hydrazide, INH) by [IrCl6]2− as a model for redox processes of such drugs in biological systems has been studied in aqueous solution as a function of pH between 0 and 8.5. Similar experiments have been performed with its isomer nicotinic hydrazide (NH). All reactions are overall second-order, first-ordA complex reaction mechanism of oxidation of the anti-tubercular prodrug isoniazid (isonicotinic hydrazide, INH) by [IrCl6]2− as a model for redox processes of such drugs in biological systems has been studied in aqueous solution as a function of pH between 0 and 8.5. Similar experiments have been performed with its isomer nicotinic hydrazide (NH). All reactions are overall second-order, first-ord

Soluble plasma proteins ST2 and CD163 as early biomarkers of nephropathy in Swedish patients with diabetes, 15–34 years of age: a prospective cohort study

BackgroundThe aim of this study was to investigate plasma levels of sST2 and sCD163 to determine whether they at an early stage could predict development of diabetic nephropathy and/or diabetic retinopathy in patients at clinical onset.MethodsPatients diagnosed with diabetes mellitus at age 15–34 years between 1987 and 1988 (n = 220) were included. Data such as BMI, smoking, HbA1c and islet cell a

Which cloud auto-scaler should i use for my application? Benchmarking auto-scaling algorithms : [Poster paper]

Rapid elasticity is one of the essential characteristics of cloud computing identified by NIST [17]. Elasticity allows resources to be provisioned and released to scale rapidly out ward and in ward according to demand. Tens - if not hundreds - of algorithms have been proposed in the literature to automatically achieve elastic provisioning [15, 23, 14, 21, 13, 20, 6, 12, 16, 10]. These algorithms a

Production of π0 and η mesons up to high transverse momentum in pp collisions at 2.76 TeV

The invariant differential cross sections for inclusive π0 and η mesons at midrapidity were measured in pp collisions at s=2.76 TeV for transverse momenta 0.4 < pT< 40 GeV/c and 0.6 < pT< 20 GeV/c, respectively, using the ALICE detector. This large range in pT was achieved by combining various analysis techniques and different triggers involving the electromagnetic calorimeter (EMCal). In particul

Non-iterative Directional Dark-field Tomography

Dark-field imaging is a scattering-based X-ray imaging method that can be performed with laboratory X-ray tubes. The possibility to obtain information about unresolvable structures has already seen a lot of interest for both medical and material science applications. Unlike conventional X-ray attenuation, orientation dependent changes of the dark-field signal can be used to reveal microscopic stru

Old and new human rights in Europe : The scope of EU rights versus that of ECHR rights

What impact will the entry of a legally binding Charter of EU Fundamental Rights have on the scope of protection of the fundamental rights of the EU citizen? How will these ‘new’ rights impact on the ‘old’ human rights in Europe? This chapter address these questions by evaluating the Strasbourg and Luxembourg legal orders. It will do so by first considering the material and personal scope of the C

Fasting levels of growth hormone are associated with carotid intima media thickness but are not affected by fluvastatin treatment

Background: Growth hormone (GH) has been linked to cardiovascular disease but the exact mechanism of this association is still unclear. We here test if the fasting levels of GH are cross-sectionally associated with carotid intima media thickness (IMT) and whether treatment with fluvastatin affects the fasting level of GH. Methods: We examined the association between GH and IMT in 4425 individuals

Analgesic antipyretic use among young children in the TEDDY study : No association with islet autoimmunity

Background: The use of analgesic antipyretics (ANAP) in children have long been a matter of controversy. Data on their practical use on an individual level has, however, been scarce. There are indications of possible effects on glucose homeostasis and immune function related to the use of ANAP. The aim of this study was to analyze patterns of analgesic antipyretic use across the clinical centers o

Work disability in non-radiographic axial spondyloarthritis patients before and after start of anti-TNF therapy : A population-based regional cohort study from southern Sweden

Objective. The aim was to assess work-loss days before and after commencement of anti-TNF treatment in patients with non-radiographic axial spondylarthritis (nr-axSpA). Methods. Bionaïve nr-axSpA patients (n = 75), aged 17-62 years, fulfilling the Assessment of SpondyloArthritis international Society criteria for axial spondyloarthritis and starting anti-TNF treatment during 2004-11, were retrieve

Metabolite profiling of LADA challenges the view of a metabolically distinct subtype

Latent autoimmune diabetes in adults (LADA) usually refers to GAD65 autoantibodies (GADAb)-positive diabetes with onset after 35 years of age and no insulin treatment within the first 6 months after diagnosis. However, it is not always easy to distinguish LADA fromtype 1 or type 2 diabetes. In this study, we examined whether metabolite profiling could help to distinguish LADA (n = 50) from type 1

Prediction of soil solution electrical conductivity by the permittivity corrected linear model using a dielectric sensor

In the present study, the electrical conductivity of the soil solution (σp) was predicted using a linear model in which the bulk soilelectrical conductivity (σb) effect on the apparent dielectric permittivity (εs) was considered. The performance of the proposed model wasevaluated by measurements with a dielectric sensor (the WET sensor) in four porous media at four different levels of electrical c

Increased nitrous oxide emissions from Arctic peatlands after permafrost thaw

Permafrost in the Arctic is thawing, exposing large carbon and nitrogen stocks for decomposition. Gaseous carbon release from Arctic soils due to permafrost thawing is known to be substantial, but growing evidence suggests that Arctic soils may also be relevant sources of nitrous oxide (N2O). Here we show that N2O emissions from subarctic peatlands increase as the permafrost thaws. In our study, t

K∗(892)0 and φ(1020) meson production at high transverse momentum in pp and Pb-Pb collisions at s NN =2.76 TeV

The production of K∗(892)0 and φ(1020) mesons in proton-proton (pp) and lead-lead (Pb-Pb) collisions at sNN=2.76TeV has been analyzed using a high luminosity data sample accumulated in 2011 with the ALICE detector at the Large Hadron Collider (LHC). Transverse momentum (pT) spectra have been measured for K∗(892)0 and φ(1020) mesons via their hadronic decay channels for pT up to 20GeV/c. The measur

An Account of Boeschian Cooperative Behaviour

According to reductionist accounts, intentional joint action can be exhaustively analysed with concepts that are already available and anyway needed for understanding intentional singular action. Most such accounts include a condition that it must be common knowledge between the participants that they have certain intentions and beliefs that causes and coordinates the joint action (a CK-condition)