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Introducing a Use-Perspective in Product Design Theory and Methodology
LUCSUS supports ongoing climate strikes
A fire safety assessment approach for evacuation analysis in underground physics research facilities
This paper introduces an integrated approach for evacuation assessment of nuclear physics research facilities exposed to fire risk. The approach combines the use of a simplified egress modelling method and advanced agent-based simulations of evacuation. An integrated multi-model approach is proposed here given the varying level of complexity concerning evacuation safety in underground physics faci
Sensorimotor stroke; Clinical features, MRI findings, and cardiac and vascular concomitants in 32 patients
Background and purpose. Sensorimotor stroke (SMS) is often included among the lacunar syndromes, although the underlying cause of this stroke-subtype is less well documented. To this end we analysed 32 patients presenting with a sensorimotor syndrome. Methods. The study protocol included vascular risk factors, echocardiography, Doppler sonography of carotid arteries, CT scan and MRI of the brain.
Glutamic acid decarboxylase - Gene to antigen to disease
Glutamic acid decarboxylase (GAD) enzymes catalyse the formation of gamma-aminobuturic acid (GABA), which is a major transmittor in the central nervous system but also exerts functions in peripheral organs. Recent molecular analyses have revealed surprising new roles for the GAD isoforms in human diseases of autoimmune character including neurological disorders and insulin-dependent diabetes. In t
Legitimacy Struggles in Global Governance : Legitimation and Delegitimation of the Asian Infrastructure Investment Bank
The Chinese-led Asian Infrastructure Investment Bank (AIIB) started operation in January 2016 in the context of severe criticism from the U.S. government and transnational civil society organizations, but with the support from major Asian and European states. The establishment of this new global governance institution (GGI) raises intriguing questions concerning legitimacy and (de)legitimation. Wh
RIFM fragrance ingredient safety assessment, coumarin, CAS Registry Number 91-64-5
Afterparty : Finansteater, Fadølsbar og fremtidslounge
Spännings- och töjningsanalys av CT-provstav för IGSCC-provning. : UPTEC 89038a R
Detection of circulating tumor cells and circulating tumor DNA before and after mammographic breast compression in a cohort of breast cancer patients scheduled for neoadjuvant treatment
PurposeIt is not known if mammographic breast compression of a primary tumor causes shedding of tumor cells into the circulatory system. Little is known about how the detection of circulating biomarkers such as circulating tumor cells (CTCs) or circulating tumor DNA (ctDNA) is affected by breast compression intervention.MethodsCTCs and ctDNA were analyzed in blood samples collected before and afte
A review of assessment methods for the urban environment and its energy sustainability to guarantee climate adaptation of future cities
The current climate change is calling for a drastic reduction of energy demand as well as of greenhouse gases. Besides this, cities also need to adapt to face the challenges related to climate change. Cities, with their complex urban texture and fabric, can be represented as a diverse ecosystem that does not have a clear and defined boundary. Multiple software tools that have been developed, in re
On Stable Crack Growth at Large Scale of Yielding.
Integration of a complete downstream process for the automated lab-scale production of a recombinant protein
In this work, an automated downstream process for the purification and formulation of a recombinant protein was integrated at lab scale in a single chromatography unit. The purification chain consists of three bind-and-elute chromatography columns, a flow-through membrane chromatography step, and a final ultrafiltration-diafiltration (UFDF) step to concentrate and formulate the sample. An integrat