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Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging.

Many psychiatric illnesses are associated with early mortality and with an increased risk of developing physical diseases that are more typically seen in the elderly. Moreover, certain psychiatric illnesses may be associated with accelerated cellular aging, evidenced by shortened leukocyte telomere length (LTL), which could underlie this association. Shortened LTL reflects a cell's mitotic history

Detection and quantification of acute myocardial ischemia by morphologic evaluation of QRS changes by an angle-based method

Objective: In acute myocardial ischemia changes within the QRS complex can add valuable information to that from the repolarization phase. This study evaluates three angles obtained from the main slopes of the R-wave within the QRS complex to assess acute myocardial ischemia. Methods: The QRS angles, denoted by empty set(R) (R-wave angle), empty set(U) (up-stroke angle) and empty set(D) (down-stro

Implementation of endoscopic submucosal dissection for early colorectal neoplasms in Sweden.

Objectives. Endoscopic submucosal dissection (ESD) is an effective method for en bloc removal of large colorectal tumors in Japan, but this technique is not yet widely established in western countries. The purpose here was to report the experience of implementing colorectal ESD in Sweden. Methods. Twenty-nine patients with primarily nonmalignant and early colorectal neoplasms considered to be too

Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion.

CD55 is a glycosylphosphatidylinositol-anchored protein, which inhibits complement activation by acting on the complement C3 convertases. CD55 is widely localized in the cholesterol rich regions of the cell plasma membrane termed membrane rafts. CD55 is attached to these specialized regions via a GPI link on the outer leaflet of the plasma membrane. Membrane rafts anchor many important signaling p

Dendritic Spine Instability Leads to Progressive Neocortical Spine Loss in a Mouse Model of Huntington's Disease.

In Huntington's disease (HD), cognitive symptoms and cellular dysfunction precede the onset of classical motor symptoms and neuronal death in the striatum and cortex by almost a decade. This suggests that the early cognitive deficits may be due to a cellular dysfunction rather than being a consequence of neuronal loss. Abnormalities in dendritic spines are described in HD patients and in HD animal

A lower crustal mafic source for the ca. 2550 Ma Qorqut Granite Complex in southern West Greenland

The late Neoarchaean Qorqut Granite Complex is the youngest large igneous intrusion in the Nuuk region in southern West Greenland, where basement is primarily of Eoarchaean and Mesoarchaean age with a tonalite-trondhjemite-granodiorite (TTG) composition. The Qorqut granite is generally undeformed and it intruded during a prolonged period, starting at ca. 2730 Ma, characterised by crustal reworking

A 2-year follow-up study of people with severe mental illness involved in psychosocial rehabilitation

Backgrounds. A focus on psychiatric rehabilitation in order to support recovery among persons with severe mental illness (SMI) has been given great attention in research and mental health policy, but less impact on clinical practice. Despite the potential impact of psychiatric rehabilitation on health and wellbeing, there is a lack of research regarding the model called the Psychiatric Rehabilitat

Revision of the European Delia pruinosa species group (Diptera: Anthomyiidae) feeding as larvae in seed capsules of Silene L. (Caryophyllaceae)

The European taxon Delia pruinosa (Zetterstedt) currently treated as one species is shown to represent a complex of several closely related species all characterized by the short antennnae, enlarged proboscis with strong, black prestomal teeth and a weak tibial setation. Biologically, all members of this Delia pruinosa species group may share the larval habit of living in seed capsules of various

Aspiration Learning in Coordination Games

We consider the problem of distributed convergence to efficient outcomes in coordination games through dynamics based on aspiration learning. Our first contribution is the characterization of the asymptotic behavior of the induced Markov chain of the iterated process in terms of an equivalent finite-state Markov chain. We then characterize explicitly the behavior of the proposed aspiration learnin

12-month outcome and predictors of recurrence in psychiatric treatment of depression – a retrospective study.

Many individuals treated for depression suffer relapse or recurrence after treatment. Known risk factors include number of previous depressive episodes and residual symptoms after treatment. Both relapse/recurrence rates and predictors of relapse/recurrence, however, may differ between various settings. To perform a naturalistic evaluation of the sustained effectiveness of treatment for adult clin

New insights into the dynamics of vacuum impregnation of plant tissues and its metabolic consequences.

The complex and highly interconnected intercellular air spaces of plant tissues occupied by gas or native liquid has offered the possibility for impregnation with a wide range of compounds. In food processing, the development of vacuum impregnation has allowed a controlled way to introduce these compounds to the tissue structure aiming at modifying structural, nutritional, and/or functional proper

The interactive effect of an AM fungus and an organic amendment with regard to improving inoculum potential and the growth and nutrition of Trifolium repens in Cd-contaminated soils

Aspergillus niger-treated dry olive cake (DryOC) can be used as a soil organic amendment and the aim of this work was to study the effectiveness of this amendment and a Cd-adapted arbuscular mycorrhizal (AM) fungus in improving Trifolium repens growth and nutrition in Cd-contaminated soil. In a compartmentalized growth system, consisting of a root compartment (RC) and two hyphal compartments (HCs)

No longer a waltz between red wine and mint tea : the portrayal of the children of immigrants in French newspapers (2003–2013)

Despite the egalitarianism that informs French civic culture, the socio-economic marginalization of citizens of non-European origin, mostly from North African countries, provide empirical evidence that challenges the French Republican ideal of integration. Such marginalization needs to be reconciled especially within the cultural realm. In this article, we look at French newspapers’ coverage of th

Is the PANSS cognitive scale measuring cognition?

Objective: To investigate the association between the Positive and Negative Syndrome Scale (PANSS) cognitive factors and cognition assessed by neuropsychological tests. Method: Ninety patients with a psychotic illness, the majority having a schizophrenia diagnosis, were assessed with PANSS ratings and tested by a comprehensive computerized neuropsychological test battery, EuCog. Results: Test perf

Monitoring Economic Development from Space: Using Nighttime Light and Land Cover Data to Measure Economic Growth

This study demonstrates estimations of economic activities on global, national, and subnational levels using remote sensing data, with a focus on developing economies. It extends a recent statistical framework which uses nighttime lights to estimate official income growth by accounting for agriculture and forestry which emit less or no additional observable nighttime light. The study argues that n

Visualisation of the rectoanal inhibitory reflex with a modified contrast enema in children with suspected Hirschsprung disease.

BACKGROUND: Patients with Hirschsprung disease lack the normal rectoanal inhibitory reflex, which can be studied with anorectal manometry or US. OBJECTIVE: To see whether the rectoanal inhibitory reflex could be visualised with a modified contrast enema, thereby increasing the diagnostic accuracy of the contrast enema and reducing the number of rectal biopsies. MATERIALS AND METHODS: Fifty-nine bo