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Multiple interferon regulatory factor and NF-κB sites cooperate in mediating cell-type- and maturation-specific activation of the human CD83 promoter in dendritic cells

CD83 is one of the best-known surface markers for fully mature dendritic cells (mature DCs), and its cell-type- and maturation-specific regulation makes the CD83 promoter an interesting tool for the genetic modulation of DCs. To determine the mechanisms regulating this DC- and maturation-specific CD83 expression, chromatin immunoprecipitation (ChIP)-on-chip microarray, biocomputational, reporter,

Software-based data acquisition and processing for neutron detectors at European Spallation Source - Early experience from four detector designs

European Spallation Source (ESS) will deliver neutrons at high flux for use in diverse neutron scattering techniques. The neutron source facility and the scientific instruments will be located in Lund, and the Data Management and Software Centre (DMSC), in Copenhagen. A number of detector prototypes are being developed at ESS together with its European in-kind partners, for example: SoNDe, Multi-G

Heat production rate in blood lymphocytes as a prognostic factor in non‐Hodgkin's lymphoma

Abstract: The heat production rate in peripheral blood lymphocytes was evaluated by direct calorimetry in 76 untreated adults with non‐Hodgkin's lymphoma (NHL). Elevated values were recorded for 20 out of 54 patients with lymphomas of high or intermediate malignancy grade (37%) and for 1 out of 22 patients (5%) with low grade lymphomas (p = 0.01). Median survival was 39 months for patients with no

Rising incidence of breast cancer among young women in Sweden

The national Swedish cancer registry was used to analyse the age-specific time trends in breast cancer incidence in Sweden from 1970 to 1984. The analysis included both a calendar year and a birth cohort approach to estimate time trends in disease occurrence. According to the birth cohort approach there was a statistically significant increase in the incidence with an average annual increase of th

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Övervakning av fåglarnas populationsutveckling : Årsrapport för 2017

I denna rapport redovisas populationstrender för 208 svenska fågelarter för olika långa tidsperioder. Fåglarna har räknats vinter, vår och sommar enligt strikt standardiserade metoder. Sommarrespektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996) men täcker hela Sverige på ett representativt sätt. Nattaktiva fåglar harWe present the results of the Swedish Bird Survey, run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2017 include data from: 575 winter point counts in 2016/2017 (42nd winter), of which 284 were carried out during the Christmas/New Year count, 223 summer point count routes (43rd year) an

Cytogenetic studies in non‐Hodgkin lymphomas‐Results from fineneedle aspiration samples

118 samples obtained by means of fine‐needle aspiration from 86 cases of non‐Hodgkin, non‐Burkitt lymphomas have been investigated cytogenetically with chromosome banding technique. If>5 times 106 cells were obtained at aspiration the success rate with the technique used was almost 70%, while if the number of cells was lower it was only about 15%. Technical aspects, and detailed cytogenetic findin

Book talks among people with chronic non-cancer pain : Literary meaning making in a shared reading group

This paper reports findings from a pilot study for the research project SHARP – Shared Reading After Pain Rehabilitation. SHARP explores the feasibility and effect of Shared Reading, a group-based reading intervention, as a way to improve the quality of life for people with chronic non-cancer pain who have undergone a pain rehabilitation programme (5 weeks) at Skåne University Hospital in Sweden.

Bayesian argumentation : The practical side of probability

We give a brief introduction to the Bayesian approach to natural language argumentation, mainly oriented to readers more familiar with classical logic. Subsequently, we summarize the gist of each of the chapters so as to provide readers with an overview of the book&s content.

Time-Stretched Spectroscopy by the Quantum Zeno Effect : The Case of Auger Decay

A tenet of time-resolved spectroscopy is "faster laser pulses for shorter timescales". Here, we suggest turning this paradigm around, and slowing down the system dynamics via repeated measurements, to do spectroscopy on longer timescales. This is the principle of the quantum Zeno effect. We exemplify our approach with the Auger process, and find that repeated measurements increase the core-hole li

Prenatal Mancozeb Exposure, Excess Manganese, and Neurodevelopment at 1 Year of Age in the Infants' Environmental Health (ISA) Study

BACKGROUND: Although growing evidence suggests that early-life excess manganese (Mn) impairs neurodevelopment, data on the neurodevelopmental effects of mancozeb, a fungicide containing Mn, and its main metabolite ethylenethiourea (ETU) are limited. OBJECTIVE: We examined whether prenatal mancozeb exposure and excess Mn were associated with neurodevelopment in 355 1-y-old infants living near banan

Comparative tissue distribution and depuration characteristics of copper nanoparticles and soluble copper in rainbow trout (Oncorhynchus mykiss)

The continuously growing number of products containing nanoparticles (NPs) makes their presence in the environment inevitable, and given the well-known toxicity of dissolved metals, concerns regarding the toxicity of metal-based NPs have been raised. Whether metal-based NPs present similar or different toxicological effects compared with metal salts is an emerging field. In the present study, rain

An Accurate Analysis of Phase Noise in CMOS Ring Oscillators

We present an accurate analysis of phase noise in ring oscillators, where each stage in the ring is a CMOS inverter loaded by a capacitance. Closed-form phase noise expressions are obtained in both 1/f2 and 1/f3 offset frequency regions, displaying an excellent agreement with numerical simulations using either ideal Verilog-A MOS models (allowing theoretical predictions to be tested with exactly t

Error Amplification in Code-based Cryptography

Code-based cryptography is one of the main techniques enabling cryptographic primitives in a post-quantum scenario. In particular, the MDPC scheme is a basic scheme from which many other schemes have been derived. These schemes rely on iterative decoding in the decryption process and thus have a certain small probability p of having a decryption (decoding) error.In this paper we show a very fundam