Ticks are known vectors of various pathogens, including bacteria, parasites and viruses, that impact both animal and human health. Improving knowledge of the distribution of tick-borne pathogens, combined with their early detection in ticks, are essential steps to fight against tick-borne diseases and mitigate their impacts. Here we give an overview of what are the common methods of pathogen detec

The Last Hour is one of plan b's series of works with spontaneous, real time text. Like How Do You Keep Talking, what we say is not rehearsed or set but happens in the moment. We set ourselves the task of saying everything we have left out of our relationship until now, as if we had one last hour together. We sit behind a long table with two microphones, dressed formally as if attending a press co

The Day the Books Took Off was a sited piece for the International English Library in Düsseldorf for the 'Stadtprojekt: Wenn die Häuser Trauer Tragen' - (When the Buildings Carry Grief) as part of Impulse Festival in 2018. The extension to the Wilhelm-Marx-Haus (one of the first skyscrapers in Europe when it was built in 1924) currently houses a number of public institutions, among them the Forum

A performance lecture based on the extensive daily recordings with a GPS that Daniel Belasco Rogers and Sophia New have been collecting, a practice they continue to the present. Within the framework of the urban choreographic lab Stadterweitern in Berlin they presented some thoughts and reflections on data, memory, daily practice, intimacy, physicality, distance and sharing space and time for deca

As part of the group show at Quartier am Hafen in Cologne the group show entitled 'Carried Landscapes' was about places of personal significance. plan b showed a print of all of their GPS traces to date.

CysK1 and CysK2 are two members of the cysteine/S-sulfocysteine synthase family in Mycobacterium tuberculosis, responsible for the de novo biosynthesis of L-cysteine, which is subsequently used as a building block for mycothiol. This metabolite is the first line defense of this pathogen against reactive oxygen and nitrogen species released by host macrophages after phagocytosis. In a previous medi

Enzymes carrying NlpC/p60 domains, for instance RipA and RipB from Mycobacterium tuberculosis, are bacterial peptidoglycan hydrolases that cleave the peptide stems and contribute to cellwall remodelling during cell division.Amember of this protein family, RipD (Rv1566c) from M. tuberculosis described in the present study, displays sequence alterations in the NlpC/p60 catalytic triad and carries a

The advent of tyrosine kinase inhibitors (TKIs) as treatment of chronic myeloid leukemia (CML) is a paradigm in molecularly targeted cancer therapy. Nonetheless, TKI-insensitive leukemia stem cells (LSCs) persist in most patients even after years of treatment and are imperative for disease progression as well as recurrence during treatment-free remission (TFR). Here, we have generated high-resolut

Children with left heart disease are at risk for developing pulmonary hypertension, initially secondary to pulmonary venous hypertension that can progress to include elevated pulmonary vascular resistance, known as combined pre- and postcapillary pulmonary hypertension. Elevated pulmonary vascular resistance may pose a risk to the right ventricle of a newly transplanted heart because of increased

BACKGROUND: The purpose of this study was to examine whether there are sex differences in vasomotor responses and receptor localization of hormones and neuropeptides with relevance to migraine (vasopressin, oxytocin, estrogen, progesterone, testosterone, amylin, adrenomedullin and calcitonin gene-related peptide (CGRP)) in human intracranial arteries.METHODS: Human cortical cerebral and middle men

The Mosul Dam, one of Iraq’s most significant infrastructural projects, has been the subject of extensive debate and scrutiny,often overshadowed by negative narratives concerning its safety and environmental impact. These narratives overlook the dam’s significant function in creating food and energy and fostering local, regional, and global water cooperation. This article seeks to provide a compre

Air pollution is a global challenge impacting the lives of millions of people, especially in low-income countries. Improving air quality is linked to several of the United Nations Sustainable Development Goals (SDGs). The state of particulate matter (PM) pollution in Ethiopia and the importance of a national ambient air quality monitoring program are discussed. The contributions of NASA’s upcoming

In this symposium piece, I reply to the diverse and wide-ranging set of objections to my book (The Open Future: Why Future Contingents are All False) set forth by MacFarlane, Green, Wasserman, and Bigg & Miller.

The accumulation of amyloid fibrils from the protein 𝛼-synuclein is a pathological hallmark of Parkinson´s disease. 𝛼-synuclein is a highly polar protein with a remarkable primary structure that can be divided into three regions: the slightly basic N-terminal region, a central hydrophobic region, and a highly acidic C-terminal tail. The C-terminal tail is of specific focus in this thesis. A chan

BACKGROUND: Pharmaceutical expenditures (PE) are increasing worldwide raising concerns about sustainability. However, the current price index provides an incomplete picture of this trend due to the rapid introduction of new drugs on the market.OBJECTIVE: The aim of this study is to decompose PE into their components and investigate the development in Sweden from 1990 to 2022.METHODS: The PE index

The importance of providing mechanisms and tools that effectively support the transition from implicit to explicit representations of Learning Design has been emphasised by previous research in the field of Technology-Enhanced Learning (TEL). In addition, the benefits of Game-based learning approaches have been long documented in the educational research literature. The paper presents the design,

Summary: We wanted to determine if there are any associations between birth factors and adult fracture risk. For women only, shorter birth length was associated with lower relative fracture risk. For women and men, individuals who were long at birth as well as tall in adulthood had a substantially higher relative fracture risk. Purpose: We aimed to examine associations between birth anthropometry