In times of runaway climate change, phasing out fossil fuels and increasing the share of renewables is imperative. But this transition is not without pitfalls as shown by a recent study of two large renewable projects in Iceland.

In this article, numerical simulations have been conducted on the heat transfer effect of dimple/protrusion layouts of a pin-finned wedge duct. Conjugate heat transfer calculations are further performed to investigate the cooling effect of modified schemes with dimples and protrusions added. Comparisons are carried out with a turbine second stage guide vane employed as the prototype. The dimple/pr

Spray-dried powders were produced from milk serum protein concentrate and lactose in varying ratios, and the rehydration characteristics of the powders were evaluated. The dissolution rate was estimated with a flow-cell based technique, and the external and internal distribution of the powder components were evaluated with X-ray photoelectron spectroscopy and confocal Raman microscopy, respectivel

In the photoreceptors of the retina, the second-messenger molecule cyclic guanosine monophosphate (cGMP) occupies centre stage in the phototransduction cascade. Remarkably, cGMP is also involved in hereditary photoreceptor degeneration caused by a variety of different genetic insults. This provides an entry point for the development of inhibitory cGMP analogues for a mutation-independent treatment

In this third of a series of papers related to cataclysmic variables (CVs) and related objects, we analyse the population of CVs in a set of 12 globular cluster models evolved with the MOCCA Monte Carlo code, for two initial binary populations (IBPs), two choices of common-envelope phase (CEP) parameters, and three different models for the evolution of CVs and the treatment of angular momentum los

Introducing the dragon simulation project, we present direct N-body simulations of four massive globular clusters (GCs) with 106 stars and 5 per cent primordial binaries at a high level of accuracy and realism. The GC evolution is computed with nbody6++gpu and follows the dynamical and stellar evolution of individual stars and binaries, kicks of neutron stars and black holes (BHs), and the effect

We very briefly discuss proposed in the literature possible scenarios for intermediate mass black holes formation in globular clusters. We also discuss the results of the MOCCA simulations of about 2000 models (BigSurvey) regarding the distribution of events connected with electromagnetic and gravitational radiations, namely: mass transfer on IMBH, collisions and mergers with IMBH and mergers with

The human pathogen Enterococcus faecalis can degrade the N-linked glycans of human RNase B to acquire nutrients, but no gene or protein has been associated with this activity. We identified an 88-kDa secreted protein, endoglycosidase (Endo) E, which is most likely responsible for this activity. EndoE, encoded by ndoE, consists of an α-domain with a family 18 glycosyl hydrolase motif and a β-domain

The optical properties of the group-III-nitride materials are obviously of direct relevance for optoelectronic applications, but experiments measuring optical properties also give information on a range of electronic properties. There is already a wealth of data in the literature on the optical properties of III-nitrides [1-4], and here we will concentrate on some of the most recent additions to t

Background The HIV-1 epidemic in Ethiopia has been shown to be dominated by two phylogenetically distinct subtype C clades, the Ethiopian (C'-ET) and East African (C-EA) clades, however, little is known about the temporal dynamics of the HIV epidemic with respect to subtypes and distinct clades. Moreover, there is only limited information concerning transmission of HIV-1 drug resistance (TDR) in t

Polyphenols may play a chemopreventive role in colorectal cancer (CRC); however, epidemiological evidence supporting a role for intake of individual polyphenol classes, other than flavonoids is insufficient. We evaluated the association between dietary intakes of total and individual classes and subclasses of polyphenols and CRC risk and its main subsites, colon and rectum, within the European Pro

OBJECTIVE: To describe the clinical and ultrasound characteristics of ovarian pure endometrioid carcinomas.METHODS: This was a retrospective multicenter study of patients with a histological diagnosis of pure endometrioid carcinoma. We identified 161 patients from the International Ovarian Tumor Analysis (IOTA) database who had undergone preoperative ultrasound examination by an experienced ultras

Statistical atmospheric rainfall downscaling, that is, statistical estimation of local or regional rainfall on the basis of large-scale atmospheric circulation, has been advocated to make the output from global and regional climate models more accurate for a particular location or basin. Neural networks (NNs) have been used for such downscaling, but their application has proved problematic, mainly

The Amazon, located in northern South America, is the world's largest river basin, and covers an area of about 6.5 million km2. The observed interannual variability in precipitation and water availability during its main discharge season has been shown to be influenced by Pacific and Atlantic Ocean sea surface temperatures (SSTs). However, the links between large-scale atmospheric motion and local

Intracellular delivery of mRNA, DNA, and other large macromolecules into cells plays an essential role in an array of biological research and clinical therapies. However, currentmethods yield a wide variation in the amount of material delivered, as well as limitations on the cell types and cargoes possible. Here, we demonstrate quantitatively controlled delivery into a range of primary cells and c

Follicular helper T cells (Tfh) are specialized helper T cells that are predominantly located in germinal centers and provide help to B cells. The development and differentiation of Tfh cells has been shown to be regulated by transcription factors, such as B-cell lymphoma 6 protein (Bcl-6), signal transducer and activator of transcription 3 (STAT3) and B lymphocyte-induced maturation protein-1 (Bl

OBJECTIVES: In this study, a systematic analysis was conducted of phasic intracoronary pressure and flow velocity in patients with severe aortic stenosis (AS) and coronary artery disease, undergoing transcatheter aortic valve replacement (TAVR), to determine how AS affects: 1) phasic coronary flow; 2) hyperemic coronary flow; and 3) the most common clinically used indices of coronary stenosis seve