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Interactive formation of statistical hypotheses in diffusion tensor imaging

When Diffusion Tensor Imaging (DTI) is used in clinical studies, statistical hypothesis testing is the standard approach to establish significant differences between groups, such as patients and healthy controls. However, diffusion tensors contain six degrees of freedom, and the most commonly used univariate tests reduce them to a single scalar, such as Fractional Anisotropy. Multivariate tests th

Decade of experimental permafrost thaw reduces turnover of young carbon and increases losses of old carbon, without affecting the net carbon balance

Thicker snowpacks and their insulation effects cause winter‐warming and invoke thaw of permafrost ecosystems. Temperature‐dependent decomposition of previously frozen carbon (C) is currently considered one of the strongest feedbacks between the Arctic and the climate system, but the direction and magnitude of the net C balance remains uncertain. This is because winter effects are rarely integrated

The effect of working hours on health

Does working time affect workers’ health behavior and health? We study this question in the context of a French reform that reduced the standard workweek from 39 to 35 hours, at constant earnings. Our empirical analysis exploits arguably exogenous variation in the reduction of working time across employers due to the reform. We find that the shorter workweek reduced smoking by six percentage point

Development of pore structure, moisture sorption and transport properties in fly ash blended cement-based materials

This study documents how the pore structure develops with time in cement-based materials with varying fly ash replacement. Heat production was measured during the first days, water vapour desorption isotherms were determined at different times up to 18 months, and moisture transport properties were measured after one year. Long-term fly ash reactions alter the pore structure considerably. The fly

ϒ production in p–Pb collisions at sNN=8.16 TeV

ϒ production in p–Pb interactions is studied at the centre-of-mass energy per nucleon–nucleon collision sNN=8.16 TeV with the ALICE detector at the CERN LHC. The measurement is performed reconstructing bottomonium resonances via their dimuon decay channel, in the centre-of-mass rapidity intervals 2.03

Climate anomalies affect annual survival rates of swifts wintering in sub-Saharan Africa

Several species of migratory swifts breed in the Western Palearctic, but they differ in reproductive traits and nonbreeding areas explored in Africa. We examined survival and recapture probabilities of two species of swifts by capture–mark–recapture data collected in northern Italy (Pallid Swift Apus pallidus in Carmagnola, Turin, and Common Swift Apus apus in Guiglia, Modena) in the breeding seas

Correlations of obstetric anal sphincter injury (OASIS) grade, specific symptoms of anal incontinence, and measurements by endoanal and transperineal ultrasound

Purpose: The aim of the study was to investigate the association between the initial grade of obstetrical anal sphincter injury (OASIS), and Wexner score parameters, with ultrasonographic findings by endoanal ultrasound (EAUS, golden standard) and transperineal ultrasound (TPUS) 6 months post-partum. Methods: Fifty-nine women after primary repair of OASIS were included at Helsingborg Hospital, Swe

Potential biomarkers for early detection of pancreatic ductal adenocarcinoma

Pancreatic cancer has the highest mortality amongst all major organ cancers. Early detection is key to reduce deaths related to pancreatic cancer. However, early detection has been challenged by the lack of non-invasive biomarkers with enough sensitivity and specificity to allow for screening. The gold standard is still carbohydrate antigen (CA 19-9), against which all new biomarkers must be evalu

Information can explain the dynamics of group order in animal collective behaviour

Animal groups vary in their collective order (or state), forming disordered swarms to highly polarized groups. One explanation for this variation is that individuals face differential benefits or costs depending on the group’s order, but empirical evidence for this is lacking. Here we show that in three-spined sticklebacks (Gasterosteus aculeatus), fish that are first to respond to an ephemeral fo

No Increased Cardiac Mortality or Morbidity of Radiation Therapy in Breast Cancer Patients After Breast-Conserving Surgery : 20-Year Follow-up of the Randomized SweBCGRT Trial

Purpose: Radiation therapy (RT) after breast-conserving surgery reduces locoregional recurrences and improves survival but may cause late side effects. The main purpose of this paper was to investigate long-term side effects after whole breast RT in a randomized clinical trial initiated in 1991 and to report dose-volume data based on individual 3-dimensional treatment plans for organs at risk. Met

Fixing and extending some recent results on the ADMM algorithm

We investigate the techniques and ideas used in Shefi and Teboulle (SIAM J Optim 24(1), 269–297, 2014) in the convergence analysis of two proximal ADMM algorithms for solving convex optimization problems involving compositions with linear operators. Besides this, we formulate a variant of the ADMM algorithm that is able to handle convex optimization problems involving an additional smooth function

Gendered dimensions of migration in relation to climate change

It is widely accepted that climate change may be contributing to population movement and has gendered effects. The relationship between climate change as a direct cause of migration continues to give rise to debates concerning vulnerabilities, while at the same time gendered dimensions of vulnerabilities remain limited to binary approaches. There is limited cross-fertilization between disciplines

Quality Assessment and Rehabilitation of Mountain Forest in the Chongli Winter Olympic Games Area, China

Spurred by the degraded forest in the 2022 Chongli Winter Olympic Games area, the Chinese government initiated a national program for mountain forest rehabilitation. We developed a method to assess the quality of mountain forests using an index system composed of stand structure, site conditions, and landscape aesthetics at three criteria levels. The method involves index weights determined by the

The paediatric global musculoskeletal task force - 'towards better MSK health for all'

There is increasing concern about the emerging global non-communicable diseases (NCDs) burden. The focus has mainly been on NCDs in adults but it is important that MSK morbidity in both children and adults is included in strategic planning. There have been considerable advances in the understanding and treatment options for children and young people (CYP) and clinical outcomes are improving for th

Uncovering the hidden diversity of litter-decomposition mechanisms in mushroom-forming fungi

Litter decomposing Agaricales play key role in terrestrial carbon cycling, but little is known about their decomposition mechanisms. We assembled datasets of 42 gene families involved in plant-cell-wall decomposition from seven newly sequenced litter decomposers and 35 other Agaricomycotina members, mostly white-rot and brown-rot species. Using sequence similarity and phylogenetics, we split the f

A review of drying methods for improving the quality of dried herbs

A large number of herb-drying studies have been conducted in recent decades and several herb-drying techniques have been introduced. However, the quality of commercial dried herbs is still lower than that of fresh herbs. In this paper, studies regarding the effect of drying techniques and pre-drying treatments on the aroma and color of dried herbs are reviewed with the aim of providing an overview

Concentrations and temporal trends in pesticide biomarkers in urine of Swedish adolescents, 2000–2017

Agricultural pesticides are extensively used for weed- and pest control, resulting in residues of these compounds in food. The general population is mainly exposed through dietary intake. Exposure to certain pesticides has been associated with adverse human health outcomes. Our aim was to assess urinary concentrations and temporal trends in the biomarkers of commonly used pesticides. Samples were

Moral choices and responsibilities: : The home-help service at the borderland of care management when older people consider relocation to a residential home

The aim of this article is to reveal how care workers in the home-help services handle the process when older people’s relocation to a residential home is under consideration. Since the care workers are engaged daily in defining care receivers’ needs and yet have no formal influence on care decisions in Sweden, the focus is on how they solve this dilemma. In this inductive study, the theoretical f

Highly efficient energy transfer from a water soluble zinc silver indium sulphide quantum dot to organic J-aggregates

The present work has been carried out with the aim to design and develop an efficient light harvesting inorganic-organic hybrid nanoscale material by employing a less toxic, environment friendly inorganic substance and also to understand the mechanism of inter-particle electronic interaction between the inorganic and organic components of the nanomaterial. Specifically, the inorganic-organic hybri

The HIV care continuum and HIV-1 drug resistance among female sex workers : a key population in Guinea-Bissau

INTRODUCTION: Female sex workers (FSW) are considered a key group for HIV transmissions in sub-Saharan Africa. The HIV Care Continuum and HIV drug resistance (HIVDR) among FSW has not been well studied in most countries in West Africa. In the current study we describe the HIV Care continuum and prevalence of HIVDR among FSW in Guinea-Bissau. METHODS: A venue-based recruitment and peer-referral of