Objective. The aim of this study was to evaluate enterocystometry, voiding pattern and urine leakage of four types of orthotopic bladder substitute. Material and methods. At eight urological departments, 78 consecutive men were studied: 66 with an ileal neobladder [30 Studer pouches (S), 24 Hautmann pouches (H) and 12 T-pouches (T)] and 12 with a right colonic [Goldwasser type (G)] neobladder. Ent

The field of cytometry has grown in scope and importance ever since the early 20th century with leaps in technology introducing the Coulter counter and the flow cytometer. Cytometry methods have brought about a revolution for the medical and biotechnology industry by providing fast and accurate analysis of cell and particle suspensions. Recent developments in the field aim at improving current cyt

Background: Women with germline BRCA1 or BRCA2 (BRCA1/BRCA2) mutations are at very high risk of developing breast cancer, including asynchronous contralateral breast cancer (CBC). BRCA1/BRCA2 genes help maintain genome stability and assist in DNA repair. We examined whether the risk of CBC associated with radiation treatment was higher among women with germline BRCA1/BRCA2 mutations than among non

Two vital pre-requisites for genetic epidemiology have been fullfiled during the past decade and have led to a virtual explosion of knowledge concerning disease risks. Reliable databases over genetic variation derived from, e.g. the HUGO and HapMap projects, coupled with technological advances make large-scale genetic analyses and downstream bioinformatics suddenly affordable. Although recent pros

England was one of the first countries to install a Compact to regulate the relationship between state and civil society and since then several other countries have followed and initiated national Agreements, Charters or Concordats. Despite a growing academic interest into such national Compact models we have insufficient knowledge of how such ideas ‘from abroad’ are adapted and molded to fit with

This paper presents the design and fabrication of a microplatform with the optimal fluidic network for an on-chip parallel "systematic evolution of ligands by exponential enrichment" (SELEX) process. The effectiveness of the optimized fluidic network for on-chip five-plex aptamer screening was verified by measuring the airflow rate at the elution ports and visualizing the specific elution during t

We describe a 65-year-old woman with a tumour adherent to the median nerve in the left forearm that was found to be a dendritic fibromyxolipoma, a distinctive benign soft tissue lesion possibly related to a myxoid spindle cell lipoma; it is a solitary fibrous tumour that may be mistaken for a sarcoma. The tumour was successfully excised with no complications.

Our aim was to identify the best diagnostic test sequence for predicting Alzheimer's disease (AD)-type dementia in subjects with mild cognitive impairment (MCI) using cerebrospinal fluid (CSF) and magnetic resonance imaging (MRI) biomarkers. We selected 153 subjects with mild cognitive impairment from a multicenter memory clinic-based cohort. We tested the CSF beta amyloid (A beta)1-42/tau ratio u

To assess the sensitivity and false positive rate (FPR) of neurological examination and somatosensory evoked potentials (SSEPs) to predict poor outcome in adult patients treated with therapeutic hypothermia after cardiopulmonary resuscitation (CPR). MEDLINE and EMBASE were searched for cohort studies describing the association of clinical neurological examination or SSEPs after return of spontaneo

Aim. This article is a report of a study of how healthcare professionals involved in surgery orientate themselves to their common task, and how this orientation can be affected by the social and organizational context. Background. Previous research indicates that surgical teams are not as cohesive as could be expected and that communication failures frequently occur. However, little is known abo

To evaluate late outcomes after fenestrated endovascular aortic repair (f-EVAR) in a tertiary European referral center.

This is the second part of a study that is following eight Swedish fathers of very preterm children using qualitative interviews. The aim was to illuminate fathers' lived experience of the 3years since the birth of their very preterm child using a hermeneutic phenomenological method. The fathers described their lived experience as a process of reorganizing life, which constituted the overarching t

The article presents and discusses the sociology of philosophy as a theory-based empirically practised sociological subdivision that came to the fore in the 1980s. In the first part, the type of empirical material and the forms of data presentation that are available to the sociology of philosophy are discussed. In the second part, the focus is on two important attempts, those of Randall Collins a

The changes in the microstructure of tomato paste suspensions have been investigated during homogenisation and subsequent shearing in suspensions with similar composition, at three tomato paste concentrations 10, 30 and 40%. The suspensions were characterised by the particle size distribution (PSD), volume fraction (empty set), and dynamic theological properties (G`, G ''). All suspensions exhibit

Measurement noise generates undesired control activity resulting in wear of actuators and reduced performance. The effects of measurement noise can be alleviated by filtering the measurement signal. New criteria based on the trade-offs between performance,robustness,and attenuation of measurement noise are proposed for assessment of the design. Simple rules for calculating the filter time constant

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews ha

The current European policy agenda strongly accentuates the importance of research and development (R&D) as a driver of economic growth. The basic assumption is that high European wage levels make it unlikely that less research-intensive parts of the economy can withstand competition from low-wage countries with increasingly skilled labour forces. Thus, the inferior growth of the European Unio

The NADH:quinone oxidoreductase (complex I) has evolved from a combination of smaller functional building blocks. Chloroplasts and cyanobacteria contain a complex I-like enzyme having only 11 subunits. This enzyme lacks the N-module which harbors the NADH binding site and the flavin and iron-sulfur cluster prosthetic groups. A complex I-homologous enzyme found in some archaea contains an F(420) de