The inherent limitations of studying gastric pathogens in vivo, prompted me to develop a 3-dimensional gastric organoid model originating from primary murine gastric tissue. In vitro cultivation of glands from primary gastric tissue robustly yields spheroidal organoids that share structural and assembly characteristics with authentic gastric tissue. Fluorescent confocal microscopy of organoids sta

Civil Society Organisations (CSOs) provide a broad range of services and are becoming increasingly involved in topics of policy and governance. At the core of any organisation are the members who constitute it, and the strength of civil society is tied to the strength of its support base. Questions of increasing participation rates are therefore not just matters of concern for fellow participants

Mega-mining extractivism is recent in Argentina. The expansion of the sector strengthened the opposition of towns which formed self-summoned neighbors’ assemblies. Women are outstanding members of these assemblies. The anti-colonialist and anti-capitalist ecofeminism of Mies and Shiva is combined with the literature on environmental justice for a feminist political ecology study of the anti-mining

The purpose of this thesis was to explore how a newly founded Youth Platform in Colombia, called La Mesa de Juventud, could affect the youth community in promoting and capacitating organizational skills, youth citizenship rights and youth influence in public policy making. The study emanates from the region of northern Cauca situated in the South Western part of Colombia which is an area where you

As a result of the increasing gang criminality, the lethal firearm violence has enhanced since the 1990’s in Sweden which is a development that has in several ways resulted in a social problem. For example are the perpetrator and thereby gang members getting younger, the connection between gang and lethal firearm violence has eventuated in a lower number of solved cases, which is partly due to the

Undersökningens två syften är att visa vilka värdegrundsrelaterade frågor som kan väckas utifrån Jessica Schiefauers romaner Pojkarna och När hundarna kommer samt hur man kan motivera att läsa dem i svenskundervisningen i gymnasieskolan. Metoden för undersökningen är litteraturstudier där romanerna och tidigare litteraturdidaktisk forskning behandlas. Resultatet av undersökningen visar dels att ro

The goal of this thesis is to investigate if the absence of an idea of a family relation between Ruth the Moabitess and King David in the Books of Samuel can be used as circumstantial evidence that could help substantiate an argument for giving the Book of Ruth a late date, a late date meaning that the Book of Ruth would have been produced later than the Books of Samuel. This will be accomplished

Detta är ett projekt på en geometrisk metod för att visualisera beräkning av kedjebråk, som har utvecklats av Lester R. Ford på 1930-talet. Beskrivningen av metoden följs med användning tekniken av Ford cirklar på tre olika fall. I motsats till ett kedjebråk med positiva heltal koefficienter, som alltid är konvergent, kan ett kedjebråk med reella koefficienter divergera. Detta projekt ger en alterThis is a project on a geometric method to visualise the calculation of continued fractions, which was developed by Lester R. Ford in the 1930s. The description of the method is followed by the use of the technique of Ford circles on three distinct cases. In contrast to a continued fraction with positive integer coefficients, which is always convergent, a continued fraction with real coefficients

Partnering börjar få en allt mer betydande roll i byggbranschen eftersom många aktörer tröttnat på att ÄTA-arbeten och olika dispyter aktörer emellan. I partnering jobbar man som ett lag mot samma gemensamma mål och för att se att vägen dit fungerar är det viktigt att göra mätningar under projektets gång. Skanska Hus har valt att satsa fullt ut på partnering och försöker inom bostadsbyggandet bli

The purpose of the study is to investigate in what ways the safety work on site differs from the recommendations in the statutory regulations. The purpose is also to determine in what ways safety precautions are taken in order to avoid the hazards of falls from heights. Furthermore, the purpose of the study is to cast light on the level of knowledge that the construction workers possess regarding

Det finns idag robotar som är särskilt anpassade för att användas av räddningsteam i följderna av katastrofer som hjälpmedel i deras arbete att lokalisera och rädda människor instängda i trånga utrymmen. De är dock mycket dyra vilket begränsar deras användande och gör att användarna tvekar innan de skickar in en robot med risken att skada eller förlora den. Detta projekt dokumenterar det första stRobots currently exist that are specifically designed for use in the wake of disasters to help rescue teams in their work of locating and rescuing individuals trapped in confined spaces. However, they are prohibitively expensive which limits their adoption and causes the operators to think twice before they're deploying a robot with the risk of losing or damaging it. This project details the f

Vid t.ex. höga blodsockervärden kan socker binda in till proteiner och bilda försockrade proteiner s.k. advanced glycation endproducts (AGE). AGE proteiner anses vara en viktig faktor i åldrande och i nedbrytande sjukdomar som diabetes och Alzheimers sjukdom. Ligander är molekyler som binder till specifika receptorer på cellytan och därigenom skickar signaler in i cellen. Receptorn för AGE proteinIn this study a method for small scale purification of the protein RAGE (receptor for advanced glycation endproducts) was developed and soluble RAGE was purified from bovine and mice tissue. In healthy animals RAGE is expressed in measurable levels only in lungs and therefore lungs have been used. The tissue was homogenized and thereafter RAGE was purified using Concanavaline A (Con A)-Sepharose,

Syfte: Studiens syfte är att undersöka hur en förtroendekris påverkar anställda i en organisation. Metod: Via en kvalitativ forskningsmetod genomfördes en fallstudie med hjälp av åtta genomförda intervjuer. Den insamlade data analyserades med en kombination av grundad teori och pattern-matching. Teoretiska perspektiv: Studiens huvudteori är agentteorin som förklarar förhållandet mellan principal o

Product Space methodology introduced in 2007 initiated a new perspective in diversification studies. It finds out stylized facts that generally developed countries mainly export core product (metal, machinery, chemicals), while developing countries mainly export periphery products (agriculture, primary goods). Besides, these two types of products have very low proximity. They do not share many com

The long-term objective within the wave energy industry is to deliver large-scale wave energy farms connected to large national power grids. However, this objective cannot be reached with today’s wave energy technologies at their current maturity levels. This has created a need within the industry to identify alternative development paths—in this thesis referred to as off-grid market opportunities

Public transport and health care constitute the top two priorities for regional authorities in Sweden. Being cost-efficient in the execution of these services is important, not only to lower the costs but also to reach maximum social benefits for the available funding. In sectors like these, where the value of what is produced is not solely measured through the consumers’ willingness to pay, maxim

How China interacts internationally can affect human rights inside and outside its borders. Therefore, the main purpose of this study was to understand China’s interaction with the United Nations Human Rights Council and its member-states. The analysis was constructed on the basis of two processes, socialization and norm shaping. These processes follow the constructivist ontology of agent and stru