DESIGN: Addison disease (AD) is a rare autoimmune disease (AID) of the adrenal cortex, presenting as an isolated AD or part of autoimmune polyendocrine syndromes (APSs) 1 and 2. Although AD patients present with a number of AID co-morbidities, population-based family studies are scarce. We aimed to carry out an unbiased study on AD and related AIDs.METHODS: We collected data on patients diagnosed

Introduction: The aim of this study was to evaluate three occupational therapy interventions, focused on supporting continued engagement in occupation among older people, to determine which intervention was most cost effective, evaluated as the incremental cost/quality adjusted life year gained. Method: The study was based on an exploratory randomized controlled trial. Participants were 77-82 year

This paper is intended to discuss the optimization of camshaft efficiency; using the rolling bearing instead of the sliding bearing within the internal combustion engines. The advantages and disadvantages of employing this new method will be accordingly identified and determined in-order to open new windows to the vehicle manufacturing industry. Following the mentioned goal; a camshaft is designed

Policy changes in the wake of Covid-19

Health economic evaluations provide decision makers with information whether the health effects of one intervention come at a reasonable cost in relation to a comparator. The existing evidence indicate that health promotion for community-dwelling older people result in a range of positive health outcomes, but there is a general lack of health economic evaluation. The aim was to evaluate cost-effec

Rationale: Symptom relief is a key treatment goal in patients with chronic obstructive pulmonary disease (COPD). However, there are limited data available on the response to bronchodilator therapy in patients at low risk of exacerbations with different levels of symptom severity. This study compared treatment responses in patients with a range of symptom severities as indicated by baseline COPD as

Background: The quality of life (QoL) of patients with osteosarcoma (OS) may be adversely affected by the disease or its treatment. Therefore, it is important to understand the QoL of patients undergoing treatment for OS to improve the QoL. We report on the first prospective international QoL study that was embedded within a large randomized clinical trial from 4 national study groups. Objective:

This book includes studies of main conflict areas in modern Western societies where religion has been a central element, ranging from popular movements and narratives of opposition to challenges of religious satire and anti-clerical critique. Special attention is given to matters of politics and gender. With this theme, it provides a useful guide to conflict areas in modern European religious hist

In order to achieve nominal performance in terms of the dynamic aperture and lifetime of a storage ring, it is important to be able to characterise and correct its second order optics. At the MAX IV 3 GeV storage ring in Lund, Sweden, the linearity of the 2nd order dispersion with chromatic sextupole field strengths has been utilised to investigate the sextupole circuits. The beating induced in th

Currently, there are few studies which examine targeted family-focused support when a family member is diagnosed with breast cancer. Thus, the aim of this study was to explore families’ experiences of participating in a family nursing intervention identified as Brief Family Health Conversations (BFamHC) following the diagnosis of breast cancer. Semi-structured family interviews were conducted with

The aim of this paper is to investigate the uses of schm-reduplications, also known as deprecative reduplications, in current corona virus related discourse. The investigation shows that schm-reduplications, such as covid schmovid, corona schmorona and pandemic schmandemic, are often used in a spirit-lifting function, to show that, despite all the threats and complications posed by the virus and n

Due to the complexity of clinical breast cancer imaging systems, their validation and optimization are challenging tasks, which require both preclinical and clinical studies. This is particularly true for systems used in breast cancer screening due to the low prevalence of disease in a screening population. Validation for screening requires clinical trials involving very large numbers of volunteer

To make autonomous, affordable ships feasible in the real world, they must be capable of safely navigating without fully relying on GPS, high-resolution 3D maps, or high-performance navigation sensors. We suggest a method for estimating the position using affordable navigation sensors (compass and speed log or inertial navigation sensor), sensors used for perception of the environment (cameras, ec

Background: The optimal way of pacing in patients with an indication for pacing and concomitant first-degree atrioventricular (AV)–block is not known, and consequently, firm guidelines on this topic are lacking. This study explored the current pacemaker programming pattern in patients with first-degree AV-block who have a dual chamber pacemaker without cardiac resynchronization. Methods: The study

Rapporten handlar om civilsamhällets ledare och bygger på en enkätundersökning som genomfördes under hösten 2017 med 140 ledare för nationella och regionala organisationer i det civila samhället i Sverige (N. 140). Syftet med rapporten är att ge en bred bild av dessa ledares positioner, de resurser de förfogar över, deras aktiviteter och inflytande, deras erfarenheter kring ledarskap och motiv til