The collapse of a massive stellar core may lead to the production of a black hole surrounded by a torus of material. Such a system is a potential source for the so-called long gamma-ray bursts (GRBs). A torus will form around the black hole if the infalling material contains sufficient angular momentum. This however requires that the core of the massive star rotates extremely rapidly prior to coll

The influence of dispersion and interaction of Graphene Oxide (GO) in semi-crystalline Polyhydroxy butyrate (PHB) and glassy amorphous Poly(tBP-oda) is explored by Positron Annihilation Lifetime Spectroscopy (PALS). The ortho-Positronium lifetimes which represent the main free volume hole size of both polymers are mainly affected by the large differences in internal stresses built up by the shrink

How are people facing a virtual agent affected by the vividness and graphical fidelity of the agent and its environment? A choice blindness (CB) experiment - measuring detection rate of hidden manipulations - was conducted presenting a high versus low immersion virtual environment. The hypothesis was that the lower quality virtual environment (low immersion) would increase the detection rate for t

Salt-inducible kinase (SIK) 3 is a virtually unstudied, ubiquitously expressed serine/threonine kinase, belonging to the AMP-activated protein kinase (AMPK)-related family of kinases, all of which are regulated by LKB1 phosphorylation of a threonine residue in their activation (T)-loops. Findings in adrenal cells have revealed a role for cAMP in the regulation of SIK1, and recent findings suggest

Crack tip conditions in SUS 304 austenitic stainless steel are studied using a constitutive model in which the martensitic phase transformation is an integral part. The phase transformation occurring in the crack tip region gives rise to fracture toughening of the material whereby the resistance against crack initiation, as well as the macroscopic material response are strongly altered by the pres

We present the first dynamical implementation of the combined GW and dynamical mean-field scheme ("GW + DMFT") for first-principles calculations of the electronic properties of correlated materials. The application to the ternary transition metal oxide SrVO3 demonstrates that this scheme inherits the virtues of its two parent theories: a good description of the local low-energy correlation physics

The purpose of the Swedish specialist examination in Emergency Medicine is not only to determine whether residents have attained the level of competence of specialists, but also to guide and facilitate residency training.

Epidemiological studies have shown an inverse relation between a whole grain consumption and risk of type-2 diabetes and cardiovascular disease. One tentative mechanism relates to colonic metabolism of indigestible carbohydrates. In a previous study, we reported a positive relation between colonic fermentation and improved glucose tolerance. This work can be seen as an extension of that study, foc

This article addresses the role of the civilizing process' in the historiography of the Victorian period. The author develops a critique of perspectives that deem the nineteenth century to be an era of discipline and self-restraint, arguing that these result from the hegemonic position of literary perspectives within Victorian Studies and their frequent reliance on Foucauldian-inspired techniques

Streptococcus pyogenes is a major human bacterial pathogen responsible for severe and invasive disease associated with high mortality rates. The bacterium interacts with several human blood plasma proteins and clarifying these interactions and their biological consequences will help to explain the progression from mild to severe infections. In this study, we used a combination of mass spectrometry

The possibility of topicalizing sentential negation is severely restricted in the Germanic V2-languages. In this paper, we show that negative preposing was more frequent and less restricted in earlier stages of Swedish: approx. 8 % of all occurrences of negation are clause initial in Old Swedish, compared to less than 0.5 % in present day Swedish. We propose that this change in frequency can be tr

Moisture induced stress in timber is dependant on many factors. The driving force behind is the moisture variation in the surrounding air which causes induced stress due to restraint of hygro-expansion within timber elements (this can to some extent be seen analogous to thermally induced stress in steel). Today's computational power together with advanced constitutive models offers aaEuro-aEuro-va

What's known on the subject? and What does the study add? Androgen stimulation of prostate cancer (PCa) cells has been the basis for extensive studies evaluating the role of androgen in PCa but the diagnostic measurement of androgen as well as androgen values that potentially influence prognosis are unclear in patients with PCa. The 50 ng/dL threshold has been questioned as a result of reports ind

Purpose: For patients with advanced melanoma, primary and secondary resistance to selective BRAF inhibition remains one of the most critically compelling challenges. One rationale argues that novel biologically informed strategies are needed to maximally cripple melanoma cells up front before compensatory mechanisms emerge. As p53 is uncommonly mutated in melanoma, restoration of its function repr

Background and objectives Barrier-enforcing measures have been suggested as treatment options for allergic rhinitis. This review identifies and describes the literature on the subject. Methods Relevant publications were searched for in the PubMed database (search entries: 'allergic rhinitis' and 'treatment'). The evaluation comprised condition (seasonal or perennial allergic rhinitis), type of int

Numerous animals are known to assess the resource holding potential of their opponents using conventional signals and other correlates of resource holding potential. Although body and weapon size generally correlate with resource holding potential and are often presumed to be visually evaluated in animal contests, no one has demonstrated visual assessment of opponent size while controlling for all

Glycoside hydrolases, which are responsible for the degradation of the major fraction of biomass, the polymeric carbohydrates in starch and lignocellulose, are predicted to gain increasing roles as catalysts in biorefining applications in the future bioeconomy. In this context, thermostable variants will be important, as the recalcitrance of these biomass-components to degradation often motivates

Low levels of vitamin D may play a role in psychiatric disorders, as cross-sectional studies show an association between vitamin D deficiency and depression, schizophrenia and psychotic symptoms. The underlying mechanisms are not well understood, although vitamin D is known to influence the immune system to promote a T helper (Th)-2 phenotype. At the same time, increased inflammation might be of i