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Detection of Perfusion Deficits in Multiphase Computed Tomography Angiography—A Stroke Imaging Technique Based on Iodine Mapping on Spectral Computed Tomography: Initial Findings

Objective: The purpose of this study was to explore a novel method forbrain tissue differentiation using quantitative analysis of multiphase computedtomography (CT) angiography (MP-CTA) on spectral CT, to assesswhether it can distinguish underperfused fromnormal tissue, using CT perfusion(CTP) as reference.Methods: Noncontrast CT and MP-CTA images from 10 patients wereanalyzed in vascular regions

Effects of crop and non-crop resources and competition : High importance of trees and oilseed rape for solitary bee reproduction

To mitigate wild bee declines, it is important to understand the separate and joint effects of parallel losses of semi-natural habitats containing flower resources and increases in transient flower resources provided by mass-flowering crops. Since mobility may affect how bee species cope with these changes, they may also affect competitive interactions and thus community composition. We focused onTo mitigate wild bee declines, it is important to understand the separate and joint effects of parallel losses of semi-natural habitats containing flower resources and increases in transient flower resources provided by mass- flowering crops. Since mobility may affect how bee species cope with these changes, they may also affect competitive interactions and thus community composition. We focused o

High dependency of chilli fruit set on wild pollinators in southern India

Ongoing pollinator declines threaten the production of many entomophilous crops. Recent reports that yields of animal-pollinated crops in India are increasing less than pollinator-independent ones suggest the occurrence of pollen limitation. We experimentally evaluated if production of the common food crop chilli benefits from insect pollination and if crop production is constrained by lack of pol

Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons

Alzheimer’s disease (AD) is the most common cause of dementia, costing about 1% of the global economy. Failures ofclinical trials targeting amyloid-βprotein (Aβ), a key trigger of AD, have been explained by drug inefficiency regardlessof the mechanisms of amyloid neurotoxicity, which are very difficult to address by available technologies. Here, wecombine two imaging modalities that stand at oppos

Neuronal α-amylase is important for neuronal activity and glycogenolysis and reduces in presence of amyloid beta pathology

Recent studies indicate a crucial role for neuronal glycogen storage and degradation in memory formation. We have previously identified alpha-amylase (α-amylase), a glycogen degradation enzyme, located within synaptic-like structures in CA1 pyramidal neurons and shown that individuals with a high copy number variation of α-amylase perform better on the episodic memory test. We reported that neuron

FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation

Aggregation of α-synuclein is associated with neurodegeneration and a hallmark pathology in synucleinopathies. These aggregates are thought to function as prion-like particles where the conformation of misfolded α-synuclein determines the traits of the induced pathology, similar to prion diseases. Still, little is known about the molecular targets facilitating the conformation-specific biological

Planning for solar access in Sweden: routines, metrics, and tools

Sweden has set ambitious goals concerning future sustainable cities. Solar energy plays a vital role in this transformation, since it directly relates to our health and well-being, on-site renewable energy production, economic activity, and social interaction. Therefore, prioritizing solar access already in the urban design phase is important to create equal possibilities for everyone living and w

Model for measuring light stability of photolabile substances in powder beds using spray dried bixin microcapsules

Light stability of different spray dried microencapsulated powders containing the natural colorant bixin was evaluated for 30 days. The encapsulating materials evaluated were sucrose, maltodextrin, and mixtures including gum arabic and pectin as encapsulation enhancers. The photostability of two sets of encapsulated material was compared: one containing purified bixin, and one being an annatto ext

Hyperpolarized MRI, functional MRI, MR spectroscopy and CEST to provide metabolic information in vivo

Access to metabolic information in vivo using magnetic resonance (MR) technologies has generally been the niche of MR spectroscopy (MRS) and spectroscopic imaging (MRSI). Metabolic fluxes can be studied using the infusion of substrates labeled with magnetic isotopes, with the use of hyperpolarization especially powerful. Unfortunately, these promising methods are not yet accepted clinically, where

The Politics and Ethics of Representation in Qualitative Research

This book offers insights on politics and ethics of representation that are relevant to researchers concerned with struggles for justice. It takes moments of discomfort in the qualitative research process as important sites of knowledge for exploring representational practices in critical research.The Politics and Ethics of Representation in Qualitative Research draws on experiences from research

Becoming ‘Unstuck’ Among Positionalities, Terms and Disciplines via Conversation (With Myself) : Exploring Potentials for Affective Reflexivity in Critical Intersex Studies

This chapter highlights the importance of collective conversations regarding how to navigate the complexity of positions, roles, stakes, interests and feelings that most researchers experience. The author explores a conversational format as a way of writing about affective reflexivity. The chapter departs in a PhD project focusing on the lived experiences of variations of sex characteristics, in o

Advancing Resilience for Sustainable Development: A Capacity Development Approach

While Africa is one of the most promising continents in the world, it is facing mounting challenges to sustainable development in terms of disaster risk, climate change, environmental degradation and demographic and socioeconomic processes. Societies are thus increasingly conceived as having to be resilient to safeguard what they value over time. However, for resilience to have any practical meani

Parameterizing standard measures of income and health inequality using choice experiments

When measuring inequality using conventional inequality measures, ethical assumptions about distributional preferences are often implicitly made. In this paper, we ask whether the ethical assumptions underlying the concentration index for income-related health inequality and the Gini index for income inequality are supported in a representative sample of the Swedish population using an internet-ba

Depressive symptoms postpartum is associated with physical activity level the year prior to giving birth - A retrospective observational study

OBJECTIVES: To examine physical activity level prior to pregnancy, during pregnancy and postpartum and investigate the association with depressive symptoms postpartum among women in Sweden.STUDY DESIGN: Retrospective observational study including 532 women on self-assessment of physical activity level before pregnancy, during pregnancy and postpartum, depressive symptoms postpartum as well as stre

Brownification in Lake Bolmen, Sweden, and its relationship to natural and human-induced changes

Study regionThis study focuses on the twelfth largest lake in Sweden, Lake Bolmen and its catchment.Study focusDuring the last decades the process of brownification has resulted in water with browner color, affecting water quality and ecosystems. The occurrence of brownification and its governing factors, especially with regard to the interaction with the environment, is not yet fully understood.

Reindeer grazing history determines the responses of subarctic soil fungal communities to warming and fertilization

Composition and functioning of arctic soil fungal communities may alter rapidly due to the ongoing trends of warmer temperatures, shifts in nutrient availability and shrub encroachment. In addition, the communities may also be intrinsically shaped by heavy grazing, which may locally induce an ecosystem change that couples with increased soil temperature and nutrients and where shrub encroachment i