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Objective: To estimate the size of regression to the mean (RTM) for common patient-reported outcomes in trials for knee osteoarthritis (OA). Design: Longitudinal cohort study; we included participants of the Osteoarthritis Initiative who fulfilled typical inclusion criteria for enrolment in a trial. These included: age 40–79 years, symptomatic knee OA, Kellgren-Lawrence grade 2–3, use of pain medi

Distinguishing between vagrancy and regular migration has proved to be challenging as vagrants may, in theory, act as pioneers in the establishment of new migration routes. Because migratory songbirds tend to follow the same orientation and migration route throughout their lives, age assessment can help to distinguish individuals which have already used a route (i.e. adults) from those using it fo

The paper shows, based on a case study of the production of a strategic plan at a fairly traditional university, the problems and potential meaninglessness of working with strategic plans in this type of setting, characterized by strong professional norms. Senior people involved in the strategy work raise strong doubts over, and distancing from, the process and outcome. Possible meanings of the st

This study evaluated the transition rates from schizotypal disorder to non-affective psychosis and schizophrenia in particular aiming to identify clinical and demographic factors associated with these transitions. We conducted a nationwide cohort study using data from the Swedish Patient Register and the Cause of Death Register, including patients aged 18 and older diagnosed with schizotypal disor

Purpose: From an active ageing perspective, investigating how adults use apps and wearables for health purposes might improve well-being strategies supported by widely adopted technologies. This study investigated adults’ perceptions of using apps and wearables for health purposes. Methods: A qualitative interview study was conducted. Adults (+18) using an app/wearable to monitor at least one heal

Background: Among non-communicable disorders (NCDs), stroke remains the second leading cause of death and the third leading cause of death and disability combined (as expressed by disability-adjusted life-years lost—DALYs) in the world. Aims: The study was aimed to estimate global, regional and nationa burden of stroke and its risk factors from 1990 to 2021. Methods: Finding presented in this pape

Manufacturing activities are highly prioritized by many low- and middle-income countries in the twentyfirst century, yet there is an urgent need for these processes to be done in a way that bring about sustainable and inclusive development. As an African forerunner that has developed manufacturing, achieved sustained growth, and undergone structural transformation, Mauritius is an interesting case

The alighting and boarding times of commuter trains play a major role for the length of dwell times and are directly influenced by the flow rate of both alighting and boarding passengers, measured as the number of passengers passing through a door per second. It is, therefore, important to have a good understanding of passenger flow rates to better understand and schedule dwell times. Where previo

In QY v Bundesrepublik Deutschland (Effect of a decision granting refugee status) the Court of Justice held that Member State are not required under EU to automatically recognize the positive decision issued by another Member State. Such a positive decision does have some significance, but very far from being anything close to automatically binding as to the positive conclusion that the applicant

BACKGROUND: Human cathelicidin LL-37 shows activity towards both gram-positive and gram-negative bacteria, and it is also active against some types of viruses. Besides its antimicrobial effects, the peptide modulates innate immunity through binding and inactivation of bacterial endotoxins and promoting chemotaxis of immune cells.RESULTS: LL-37 is reported to interact with plasma membrane receptors

Understanding reactive flows is crucial for advancing energy production, combustion efficiency, and plasma- assisted chemical processes. These systems often involve short-lived radicals and transient phenomena that require high-resolution, non-intrusive diagnostic techniques for accurate characterization. This thesis focuses on the development of advanced non-linear laser-based imaging methods to

The aim of the present study was to extend the creatinine-based Lund-Malmö GFR equation for use with rescaled cystatin C (r-LMRCys) and validate it against measured GFR (mGFR) in the EKFC cystatin C cohort of children (n = 2,293) and adults (n = 7,727). Rescaling was obtained by dividing each biomarker by a Q-value, representing the population-specific median biomarker level among healthy individu