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Purpose: To characterize the clinical phenotype, with emphasis on electrophysiology, of two children with suspected Bothnia dystrophy. Methods: Two unrelated affected patients, 10 and 11 years old, were studied. Ophthalmological examination included testing of visual acuity, fundus inspection and fundus photography, kinetic perimetry, full-field electroretinogram (ERG), and multifocal ERG. The pre

Lipid droplets are cytoplasmic organelles which serve as storage sites for neutral lipids. Adipose differentiation-related protein (ADRP) is intrinsically associated with the surface of lipid droplets and is believed to play a major role in the maintenance of lipid stores in non-adipocytes. ADRP abundance is intimately linked to the amount of lipid found within cells and agents which increase the

PURPOSE: A spin-echo diffusion-sensitized pulse sequence using high gradients (23 mT/m) is introduced. MATERIAL AND METHODS: In order to minimize motion artefacts, velocity-compensating gradients, ECG-triggering and post-processing with phase correction and raw data averaging using navigator echoes was performed. The in vitro ratio of diffusion coefficients for water and acetone was determined and

In this report, which is the first in a series of three reports, an existing computer control system in a heavy-duty truck from Volvo Truck Corporation has been investigated. The aim of the report and of the DICOSMOS case study at Volvo Technological Development is to design and study a future computer control system for a truck and semi-trailer vehicle combination. The functionality in focus is v

The theoretical background and research evidence supporting two alternative scenarios – worsening health and improving health at increasing life expectancy is analyzed. It is shown that the prevailing “longer life – worse health” theory is based on the logic that due to the reduced birth-rate and increased proportion of older citizens the process of population aging is taking place, leading to an

Specific hydroxy groups of the terminal disaccharide unit of globotriaosyl ceramide (Gb(3)Cer) were identified from binding studies with deoxyGb(3)Cer and verotoxins (VTs) [Nyholm, Magnusson, Zheng, Norel, Birmington-Boyd and Lingwood (1996) Chem. Biol. 3, 263-275]. Four such hydroxy groups (2", 4", 6" and 6') were each substituted with an amino group and the corresponding deoxyamino globotrioses

Popular Abstract in Swedish Avhandlingens huvudfråga är hur språket används i skolämnet naturkunskap i två mångkulturella gymnasieklassrum. Språket ses som vår viktigaste resurs för utveckling och lärande i olika skolämnen. Att elever får rikliga tillfällen att lära sig hantera ämnesrelevant språk blir enligt ett sådant synsätt avgörande för vilket språk de utvecklar och vad de lär sig. SpråkutvecThe purpose of the thesis is to investigate how language is used in the school subject Natural Science in two multi-cultural upper seconday classrooms. Previous research points to the fact that second language students are not successful in their school work. The reason usually given is the students' inadequate knowledge of their second language. Today's curricular directives of the Swedish school

Several photosensitizers were screened for their tumour-marking ability using laserinduced fluorescence in Wistar/Furth rats bearing subcutaneous adenocarcinomas inoculated in muscle. Of the studied photosensitizers, dihaematoporphyrin ether appeared to exhibit the best tumour-demarcation properties. Polyhaematoporphyrin ester and tetrasulfonated phthalocyanine were almost as good although the flu

Popular Abstract in Swedish Istället för fred gav det kalla krigets slut upphov till nya säkerhetspolitiska utmaningar i form av inomstatliga konflikter. Under perioden 1989-2000 utkämpades 111 väpnade konflikter runt om i världen varav de flesta kan karakteriseras som inomstatliga, såsom inbördeskriget i Somalia, det våldsamma sammanbrottet i Jugoslavien, och folkmordet i Rwanda. Trots att både hThis study is concerned with tracing the process of how conflict prevention is moving from the realm of ideas to the field of action. Why is it that, despite historical as well as recent evidence of the infeasibility to prevent wars, the idea of conflict prevention has resurfaced to meet the challenge of the new wars of the post-Cold War era? The study investigates whether the growing interest in

Structural properties of the acidic proline rich protein PRP-1 of salivary origin in bulk solution and adsorbed onto a negatively charged surface have been studied by Monte Carlo simulations. A simple model system with focus on electrostatic interactions and short-ranged attractions among the uncharged amino acids has been used. In addition to PRP-1, some mutants were considered to assess the role

We discuss the main properties of the Galactic globular cluster (GC)blue straggler stars (BSSs), as inferred from our new catalog containingnearly 3000 BSSs. The catalog has been extracted from thephotometrically homogeneous V versus (B-V) color-magnitude diagrams(CMDs) of 56 GCs, based on Wide Field Planetary Camera 2 images of theircentral cores. In our analysis, we used consistent relative dist