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Platelets are versatile cells which are capable of eliciting nonhemostatic immune functions, especially under inflammatory conditions. Depending on the specific setting, platelets may be either protective or pathogenic in acute lung injury and acute respiratory distress syndrome (ARDS). Their role in transfusion-related acute lung injury (TRALI) is less well defined; however, it has been hypothesi
Digital and scalable technologies are increasingly important for rapid and large-scale assessment and monitoring of land cover change. Until recently, little research has existed on how these technologies can be specifically applied to the monitoring of Reducing Emissions from Deforestation and Forest Degradation (REDD+) activities. Using the Google Earth Engine (GEE) cloud computing platform, we
We present a model of how counting is learned based on the ability to perform a series of specific steps. The steps require conceptual knowledge of three components: numerosity as a property of collections; numerals; and one-to-one mappings between numerals and collections. We argue that establishing one-to-one mappings is the central feature of counting. In the literature, the so-called cardinali
High spatial resolution X-ray microscopy has become a dedicated tool to study nanocrystals and nanostructure devices in recent years. In general, the spatial resolution of X-ray microscopy depends on the spot size of the X-ray beam and the pixel size of X-ray detectors. High-resolution X-ray detection ideally requires a minimal active region with a sufficient thickness for the X-ray absorption, wh
Objectives: To investigate the prevalence of pathological disease and spectrum of human papillomavirus (HPV) types among symptomatic foreskin tissue. Patients and Methods: Consecutively excised symptomatic foreskins from 351 men were sent for histopathological evaluation. During the surgical procedure, a fresh biopsy was taken for HPV analysis by modified general primer polymerase chain reaction.
Optically stimulated luminescence (OSL) signal properties of pellets from three types of NaCl (two household salts and one analytical grade salt) were investigated for their use in prospective dosimetry. Special attention was given to the OSL signal behaviour with time. The readout protocol was optimised in terms of preheat temperature, and the OSL signal yield of the NaCl pellet with time as well
Purpose: The purpose of the paper is to build on current discussions about the need for and role of guidance in learning and teaching, as well as to theoretically develop its specifics to further advance our scholarly understanding of how to structure and enhance entrepreneurship education. Design/methodology/approach: The paper takes a synthesizing conceptual approach, built on developmental psyc
This thesis examines so-called pancake sentences, an agreement anomaly found in Swedish, Danish and Norwegian. In these languages, predicative adjectives typically agree with their subjects in number and grammatical gender. However, with certain subjects the predicative takes a t-form, corresponding to singular neuter, regardless of the number and gender of the subject. Such sentences are commonlyThis thesis examines so-called pancake sentences, an agreement anomaly found in Swedish, Danish and Norwegian. In these languages, predicative adjectives typically agree with their subjects in number and grammatical gender. However, with certain subjects the predicative takes a t-form, corresponding to singular neuter, regardless of the number and gender of the subject. Such sentences are commonly
The coronavirus disease 2019 (COVID-19) pandemic has created a global health- and economic crisis. Detection of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19 by serological methods is important to diagnose a current or resolved infection. In this study, we applied a rapid COVID-19 IgM/IgG antibody test and performed serology assessment of antibody
Excessive risk-taking in markets can have devastating consequences as the latest financial crises have highlighted. In this paper, we ask whether markets as an institution encourages such excessive risk-taking. To establish causality, we isolate the effects of market interaction in a laboratory experiment keeping other possibly confounding factors constant. We find that the opposite is true. Marke
Background: We evaluated outcome after carpal tunnel release (CTR) in patients with clinically diagnosed carpal tunnel syndrome (CTS) but normal results in nerve conduction studies (NCS), and compared these results with those from a prospective group of patients with NCS-verified CTS. Methods: Over a 5-year period, we prospectively included 103 patients with clinical CTS. NCS were done at inclusio
OBJECTIVE: Negative pressure wound therapy (NPWT) is commonly used in the continuous mode. Intermittent pressure therapy (IPT) results in faster wound healing, but it often causes pain. Variable pressure therapy (VPT) has therefore been introduced to provide a smooth transition between 2 different pressure environments, thereby maintaining the negative pressure environment throughout the therapy.
Aims/hypothesis: The risk of complications and medical consequences of type 2 diabetes are well known. Hospital costs have been identified as a key driver of total costs in studies of the economic burden of type 2 diabetes. Less evidence has been generated on the impact of individual diabetic complications on the overall societal burden. The objective of this study was to analyse costs of hospital
Background and purpose — Hallux rigidus (HR) may cause decreased range of motion, joint pain, and gait disturbances. There is a lack of evidence regarding the outcome of different surgical procedures for moderate HR. We report patient-reported outcomes after joint-preserving surgical procedures for moderate HR. Patients and methods — We included 296 patients registered in Swefoot (Swedish national
Background: Testing for prostate-specific antigen (PSA) levels in blood are widely used and associated with prostate cancer risk and outcome. After puberty, PSA levels increase by age and multiple single nucleotide polymorphisms (SNPs) have been found to be associated with PSA levels. However, the relationship between the effects of SNPs and age on PSA remains unknown. Methods: To test for SNP × a
Diffusion MRI techniques are used widely to study the characteristics of the human brain connectome in vivo. However, to resolve and characterise white matter (WM) fibres in heterogeneous MRI voxels remains a challenging problem typically approached with signal models that rely on prior information and constraints. We have recently introduced a 5D relaxation–diffusion correlation framework wherein
The umbilical artery lumen closes rapidly at birth, preventing neonatal blood loss, whereas the umbilical vein remains patent longer. Here, analysis of umbilical cords from humans and other mammals identified differential arterial-venous proteoglycan dynamics as a determinant of these contrasting vascular responses. The umbilical artery, but not the vein, has an inner layer enriched in the hydrate
Tourism is a major socioeconomic contributor to established and emerging destinations in the Mediterranean region. Recent studies introducing the Holiday Climate Index (HCI) highlight the significance of climate as a factor in sustaining the competitiveness of coastal and urban destinations. The aim of this study is to assess the future HCI performance of urban and beach destinations in the greate
Understanding the kinetics of peptide self-assembly is important because of the involvement of peptide amyloid fibrils in several neurodegenerative diseases. In this paper, we have studied the dissolution kinetics of self-assembled model peptide fibrils after a dilution quench. Due to the low concentrations involved, the experimental method of choice was isothermal titration calorimetry (ITC). We
A10K (A=alanine, K=lysine) model peptides self-assemble into ribbon-like β-sheet aggregates. Here, we report an X-ray diffraction investigation on a flow-aligned dispersion of these self-assembly structures. The two-dimensional wide-angle X-ray scattering pattern suggests that peptide pack in a two-dimensional oblique lattice, essentially identical to the crystalline packing of polyalanine, An (fo
