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Background, experience of abuse, and mental health among adolescents in out-of-home care : a cross-sectional study of a Swedish high school national sample

Purpose: To compare experiences for adverse events, especially sexual abuse, and mental health in a group of high school students in out-of-home care with a representative sample of peers of the same age and similar educational attainment living with their parents. Materials and methods: A sample of 5839 students in the third year of Swedish high school, corresponding to a response rate of 59.7%,

Dödsbränder i bostäder 2012-2015 : En studie av fastighetsinformation

I Sverige inträffar runt 5500 bränder i bostäder årligen och i ca 80 av dessa bränder omkommer en eller flera personer. Det finns en långsamt nedåtgående trend för antalet omkomna i landet och världen, men nedgången är långsam och det finns inte heller några tydliga indikationer på vad denna nedgång kan beror på.Syftet med detta arbete är att studera olika byggnadstekniska faktorer i bostäder där The purpose of this work is to study fatal residential fires and see if they are correlated with any specific building characteristics. In this report, data on fatal fires are paired with data about the properties where the fires occurred. The analysis has shown that apartment buildings are overrepresented among properties with fatal fires compared to single-family units and agricultural units. It

Hyperthyroidism as a late effect in childhood cancer survivors - an Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study

Background: Hyperthyroidism is a rare disorder which may negatively affect health and quality of life. Its occurrence in childhood cancer survivors has not previously been investigated in detail. Material and methods: In the hospital registers of the five Nordic countries, 32,944 childhood cancer survivors and 212,675 population comparisons were followed for the diagnosis of hyperthyroidism. Hospi

Uncertainty quantification, propagation and characterization by Bayesian analysis combined with global sensitivity analysis applied to dynamical intracellular pathway models

Motivation: Dynamical models describing intracellular phenomena are increasing in size and complexity as more information is obtained from experiments. These models are often over-parameterized with respect to the quantitative data used for parameter estimation, resulting in uncertainty in the individual parameter estimates as well as in the predictions made from the model. Here we combine Bayesia

Osteoporosis knowledge and awareness among university students in Saudi Arabia

Awareness and knowledge about any disease is the first step to prevent and treat it, so this study evaluates osteoporosis awareness and knowledge in university students. Our results showed a high awareness and good knowledge of osteoporosis. Females were better informed than males. Knowledge increased with increasing education level. PURPOSE: Osteoporosis is a worldwide health problem, including S

Psychosis in Systemic Lupus Erythematosus : Results From an International Inception Cohort Study

Objective: To determine, in a large, multiethnic/multiracial, prospective inception cohort of patients with systemic lupus erythematosus (SLE), the frequency, attribution, clinical, and autoantibody associations with lupus psychosis and the short- and long-term outcomes as assessed by physicians and patients. Methods: Patients were evaluated annually for 19 neuropsychiatric (NP) events including p

Using a Targeted Proteomics Chip to Explore Pathophysiological Pathways for Incident Diabetes- The Malmö Preventive Project

Multiplex proteomic platforms provide excellent tools for investigating associations between multiple proteins and disease (e.g., diabetes) with possible prognostic, diagnostic, and therapeutic implications. In this study our aim was to explore novel pathophysiological pathways by examining 92 proteins and their association with incident diabetes in a population-based cohort (146 cases of diabetes

Initial correlated states for the generalized Kadanoff–Baym Ansatz without adiabatic switching-on of interactions in closed systems

We reconsider the Generalized Kadanoff–Baym Ansatz (GKBA) approximation for non-equilibrium Green’s functions and extend it to self-consistently define an equilibrium correlated (within GKBA) state in closed systems. The advantage of the proposed prescription is to avoid the preparation of the initial equilibrium correlated state via adiabatic switching-on of the correlations. A simple model syste

Familial risk for soft tissue tumors : A nation-wide epidemiological study from Sweden

Purpose: Reliable data on familial risks are important for clinical counseling and cancer genetics. However, population-based studies on familial soft tissue tumors are limited, which we will examine. Methods: Adjusted standardized incidence ratios (SIRs), calculated from the nation-wide Swedish Family Cancer Database, were used to measure the familial risk. Results: There were 17 offspring-parent

Dynamics of multiple protoplanets embedded in gas and pebble discs and its dependence on Σ and ν parameters

Protoplanets of super-Earth size may get trapped in convergence zones for planetary migration and form gas giants there. These growing planets undergo accretion heating, which triggers a hot-Trail effect that can reverse migration directions, increase planetary eccentricities, and prevent resonant captures of migrating planets. In this work, we study populations of embryos that are accreting pebbl

Predictive value of minimal residual disease in philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies

The prognostic value of minimal residual disease (MRD) in Philadelphia-chromosome-positive (Ph+) childhood acute lymphoblastic leukemia (ALL) treated with tyrosine kinase inhibitors is not fully established. We detected MRD by real-time quantitative polymerase chain reaction (RQ-PCR) of rearranged immunoglobulin/T-cell receptor genes (IG/TR) and/or BCR/ABL1 fusion transcript to investigate its pre

Heat transfer study on a hybrid smooth and spirally corrugated tube

Corrugated tubes are widely used in a range of applications for heat transfer enhancement. The spirally corrugated tube has a better heat transfer performance than the smooth tube. In this paper, the heat transfer performance of a hybrid smooth and six-start spirally corrugated tube is studied. With a validated numerical model, the effects of the corrugation part length on the vortex in the downst

Probing the Virtual Proteome to Identify Novel Disease Biomarkers

BACKGROUND: Proteomic approaches allow measurement of thousands of proteins in a single specimen, which can accelerate biomarker discovery. However, applying these technologies to massive biobanks is not currently feasible because of the practical barriers and costs of implementing such assays at scale. To overcome these challenges, we used a "virtual proteomic" approach, linking genetically predi

Coronary heart disease risks in first- and second-generation immigrants in Sweden : a follow-up study

OBJECTIVES: To analyse whether there is an association between country of birth in first-generation immigrants and first hospitalization for or death from coronary heart disease (CHD) and to analyse whether this association remains in second-generation immigrants.DESIGN: In this follow-up study, the MigMed database at the Karolinska Institute, Stockholm, was used to identify all hospital diagnoses