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General anaesthesia impairs respiratory function in overweight patients. We wanted to determine whether increased tidal volume (VT), with unchanged end-tidal carbon dioxide partial pressure (PETCO2), affects blood concentrations of oxygen and sevoflurane in overweight patients.

In this paper the Triple Annular Research Swirler, a fuel injector characterized by complex design with three concentric air passages, has been studied numerically. A swirl-stabilized lean premixed flame has been simulated by means of Large Eddy Simulation. The computations characterize successfully the dynamics of the flame and their interactions with the complex swirling flow. The flame is stabi

We report a search for gravitational waves from the inspiral, merger and ringdown of binary black holes (BBH) with total mass between 25 and 100 solar masses, in data taken at the LIGO and Virgo observatories between July 7, 2009 and October 20, 2010. The maximum sensitive distance of the detectors over this period for a (20, 20)M-circle dot coalescence was 300 Mpc. No gravitational wave signals w

The purpose of the study was to assess the prevalence of pulmonary embolism (PE) and other lung diseases among pregnant women with suspected PE and to calculate the radiation exposure to patient and fetus in this population. As a secondary aim, we evaluated the negative predictive value of a normal ventilation/perfusion single photon emission computed tomography (V/P SPECT) examination in pregnanc

INTRODUCTION: This study assessed short and long term effects of a 3-year controlled school-based physical activity (PA) intervention on fatness, cardiorespiratory fitness (VO2peak) and cardiovascular disease (CVD) risk factors in children. METHODS: The study involved 18 schools (10 intervention and 8 controls) and included a follow-up 4 years after the end of intervention. The analyses included 6

We consider evolution equations generated by quadratic operators admitting a decomposition in creation-annihilation operators without usual ellipticity-type hypotheses; this class includes hypocoercive model operators. We identify the singular-value decomposition of their solution operators with the evolution generated by an operator of harmonic oscillator type, and in doing so derive exact charac

Background: Respiratory supercomplexes are known to exist, but their function remains to be revealed. Results: Plant supercomplexes are affected by hypoxia and a concomitant drop in pH. Conclusion: Respiratory supercomplexes are dynamic structures that are affected by the intracellular environment. Significance: Supercomplexes could have a regulatory function in guiding electrons through alternati

Background: Cyclophosphamide induction regimens for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis are effective in 70 to 90% of patients, but they are associated with high rates of death and adverse events. Treatment with rituximab has led to remission rates of 80 to 90% among patients with refractory ANCA-associated vasculitis and may be safer than cyclophosphamide regimens. Me

Introduction Many studies deal with taxonomic diversity (TD) or estimation of functional traits of ectomycorrhizal communities. However, to our knowledge, none of them has ever tried to calculate the functional diversity (FD) of those communities, which is of critical importance for the diversity and reliability of nutrient supply to the tree. Objectives Here, we propose to evaluate the functional

In this work we present the results of in situ synchrotron X-ray diffraction measurements of fatigue crack-tip strain fields following a 100% overload (OL) under plane strain conditions. The study is made on a bainitic steel with a high toughness and fine microstructure. This allowed a very high (60 mu m) spatial resolution to be achieved so that fine-scale changes occurring around the crack-tip w

Hox genes are recognized for their explanatory power of bilateral development. However, relatively little is known about natural variation in, and the evolutionary dynamics of, Hox genes within wild populations. Utilizing a natural population of sand lizards (Lacerta agilis), we screened HoxA13 for genetic variation and an association with incidence of offspring malformations. We found significant

Most wastewater treatment plants contain an activated sludge process, which consists of a biological reactor and a sedimentation tank. The purpose is to reduce the incoming organic material and dissolved nutrients (the substrate). This is done in the biological reactor where micro-organisms (the biomass) decompose the substrate. The biomass is then separated from the water in the sedimentation tan

During the last two decades, the synthesis of silica with an ordered mesoporous structure has been thoroughly explored. The basis of the synthesis is to let silica monomers polymerize in the presence of an amphiphilic template component. In the first studies, cationic surfactants were used as structure inducer. Later it was shown that pluronic copolymers also could have the role. One advantage wit

This article summarizes the contributions in this special issue on Diffraction-Limited Storage Rings. It analyses the progress in accelerator technology enabling a significant increase in brightness and coherent fraction of the X-ray light provided by storage rings. With MAX IV and Sirius there are two facilities under construction that already exploit these advantages. Several other projects are

Close collaboration is considered important; but is close collaboration for all purchases necessary to create value-in-production? In construction as well as in other industries, companies purchase a variety of items that require different amounts of attention to the relationship with suppliers. Buyer-supplier relationships are investigated in relation to how they bring value-in-production in the

Although Markov chain Monte Carlo (MC) simulation is a potentially powerful approach for exploring conformational space, it has been unable to compete with molecular dynamics (MD) in the analysis of high density structural states, such as the native state of globular proteins. Here, we introduce a kinetic algorithm, CRISP, that greatly enhances the sampling efficiency in all-atom MC simulations of