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BACKGROUND: Sphingomyelin occurs in modest amounts in the diet, in sloughed mucosal cells, and in bile. It is digested by the mucosal enzymes alkaline sphingomyelinase and ceramidase. In humans, alkaline sphingomyelinase is also secreted in bile. The digestion of sphingomyelin is slow and incomplete, which has been linked to the inhibition of cholesterol absorption and colonic carcinogenesis. OBJE
New combustion engine principles increase the demands on feedback combustion control, at the same time economical considerations currently enforce the usage of low-end control hardware limiting implementation possibilities. Significant development is simultaneously and continuously carried out within the field of Field Programmable Gate Arrays (FPGAs). In recent years FPGAs have developed, from
OBJECTIVE: To assess the inter-tester reliability of the New Mobility Score in patients with acute hip fracture. DESIGN: An inter-tester reliability study. SUBJECTS: Forty-eight consecutive patients with acute hip fracture at a median age of 84 (interquartile range, 76-89) years; 40 admitted from their own home and 8 from nursing homes to an acute orthopaedic hip fracture unit at a university hosp
Popular Abstract in Swedish Den här avhandlingen handlar om utvecklingen av CARS som en diagnostikmetod för att studera förbränningsförlopp. CARS står för Coherent Anti-Stokes Raman spectroscopy och är en optisk laserbaserad metod för att mäta temperaturer och ämneskoncentrationer i gaser. CARS, och andra typer av förbränningsdiagnostikmetoder, bidrar till ökad förståelse för de processer som utgöDuring the last decades, coherent anti-Stokes Raman spectroscopy (CARS) has been an important tool in combustion research. The focus of this thesis is the improvement of the capability of the pure rotational CARS (RCARS) technique for this type of applications. The technique is used to measure temperatures and relative species concentrations in the gas phase and thermometry is performed by fitting
Background and aims The vasopressin analogue desmopressin has demonstrated efficacy in decreasing bleeding time by increasing the circulating levels of coagulation factor VIII and von Willebrand factor, but also by direct effects on platelets. Previous studies have demonstrated contrasting results regarding the effect of desmopressin on platelets in vitro. The aim of this study was to investigate
Parkinson's Disease (PD) is the second most common neurodegenerative disorder of the central nervous system. Motor symptoms are the focus of pharmacotherapy, yet non-motor features of the disease (e.g. fatigue, mood disturbances, sleep disturbances and symptoms of anxiety) are both common and disabling for the patient. The pathophysiological mechanisms behind the non-motor symptoms in PD are yet t
Increased epithelial cell expression of the cyclooxygenase-2 (COX-2) enzyme is a characteristic event of both inflammatory bowel disease and colon cancer. We here report the novel findings that collagen I-induced de novo synthesis of COX-2 in intestinal epithelial cells is inhibited by pertussis toxin (PTX) and by an inhibitory peptide selective for the heterotrimeric G alpha(i3)-protein. These fi
A new collaborative program, the FERRUM project. aims at extending and improving the database of oscillator strengths for the astrophysical important Fe II spectrum. In this paper we report on the experimental method applied for measurements of radiative lifetimes of Fe II levels at intermediate excitation (5-10 eV) that can be populated ba laser excitation from metastable states. The technique in
BACKGROUND: In settings with low background prevalence of tuberculosis (TB) infection, interferon-gamma release assays (IGRA) could be useful for diagnosing active TB. This study aims to evaluate the performance of QuantiFERON-TB Gold (QFT-G) in the investigation for suspected active TB, with particular attention to patients originating in high-incidence countries. Furthermore, factors associated
