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Three essays on our planetary future

Föreliggande avhandling argumenterar för värdet av ett långsiktigt planetärt perspektiv i politiken. Vi har blivit vana att tänka på de risker som moderniteten genererar utifrån ett vidgat tidsligt och rumsligt perspektiv (till exempel utgör år 2100 en återkommande referenspunkt för forskningen kring globala klimatförändringar). På samma sätt bör vi fråga oss vilka politiska möjligheter som mänsklThis thesis propounds a techno-environmentalist position. Seeking to combine the need for natural restoration with human development, the thesis explores to what extent more radical forms of ecological modernization can offer a basis for political compromise and open new paths to global long-term sustainability. Based on three published articles, the thesis engages with existing literature on (a)

The value of IgG-uria in predicting renal failure in idiopathic glomerular diseases. A long-term follow-up study.

Abstract Background. Proteinuria is the hallmark of glomerular disease and non-selective proteinuria is often associated with progression to renal failure. The predictive value of urine IgG excretion was studied comprehensively in patients with nephrotic syndrome. In the present follow-up study, we examine the predictive value of IgG-uria in patients with idiopathic glomerular diseases with a wide

Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice

We used concanavalin A (Con A)-induced liver injury to study the role of galectin-3 (Gal-3) in the induction of inflammatory pathology and hepatocellular damage. We tested susceptibility to Con Ainduced hepatitis in galectin-3-deficient (Gal-3-/-) mice and analyzed the effects of pretreatment with a selective inhibitor of Gal-3 (TD139) in wild-type (WT) C57BL/6 mice, as evaluated by a liver enzyme

Search for flavour-changing neutral current top-quark decays to q Z in pp collision data collected with the ATLAS detector at root s=8 TeV

A search for the flavour-changing neutral-current decay is presented. Data collected by the ATLAS detector during 2012 from proton-proton collisions at the Large Hadron Collider at a centre-of-mass energy of root s = 8 TeV, corresponding to an integrated luminosity of 20.3 fb(-1), are analysed. Top-quark pair-production events with one top quark decaying through the t -> qZ (q = u,c) channel and t

Increasing amperometric biosensor sensitivity by length fractionated single-walled carbon nanotubes.

In this work the sensitivity-increasing effect of single-walled carbon nanotubes (SWCNTs) in amperometric biosensors, depending on their average length distribution, was studied. For this purpose the SWCNTs were oxidatively shortened and subsequently length separated by size exclusion chromatography. Transmission electron micrographs of different fractions of SWCNTs were collected. Diaphorase "wir

Aqueous phase behavior of salt-free catanionic surfactants: the influence of solubility mismatch on spontaneous curvature and balance of forces

In this paper, we investigate the phase behavior and microstructure for a series of salt-free catanionic surfactants of the type Cm+Cn- with varied chain length mismatch (m not equal n), using light microscopy, DSC, turbidity, surface tension, SAXS and SANS. The compounds consist of alkyltrimethylammonium alkylsulfonates, denoted by TA(m)So(n). Depending on the asymmetry between both ions, three r

Bayesian calibration of a model describing carbon, water and heat fluxes for a Swedish boreal forest stand

This study quantified major fluxes of carbon (C), heat and water, including uncertainty estimates, in a boreal forest in northern Sweden, using a process-based model (Coup-Model) and Bayesian calibration methodology. Coupled C, water and heat fluxes were described together with estimated uncertainties for all major components of the simulated C budget. Simulated mean gross primary production was 6

Low-carbon district heating in Sweden – Examining a successful energy transition

District heating (DH) systems may contribute to reducing the use of fossil fuels for heating purposes since they enable the use of waste heat and facilitate the use of renewable energy sources. This paper focuses on the transformation of the Swedish DH systems with regard to energy supply in 1960–2011. Swedish DH production was completely dependent on oil until the late 1970s, while today it is do

Migration of the Little Ringed Plover Charadrius dubius breeding in South Sweden tracked by geolocators

Capsule Little Ringed Plovers breeding in South Sweden migrate towards the southeast in the autumn, via the Middle East, to winter in Saharan and sub-Saharan locations or in India, while the spring migration is more directly towards the north.Aims To study the migration routes and wintering area of Little Ringed Plovers (Charadrius dubius) breeding in South Sweden, and to investigate the migration

Internal and External Knowledge and Introduction of Export Varieties

Firms in local industries maintain their capability to generate new export varieties by simultaneously exploiting internal and external knowledge resources. The paper introduces the notion variety triplet' to distinguish individual export varieties, where a triplet is a unique combination of a firm, a product code and a destination country. For each date, the set of variety triplets in each local

Excellent long-term results of the Müller acetabular reinforcement ring in primary total hip arthroplasty.

Background and purpose - The original Müller acetabular reinforcement ring (ARR) shows favorable medium-term results for acetabular reconstruction in total hip arthroplasty, where it is used when the acetabular bone stock is deficient. However, there are no data regarding long-term survival of the device. We therefore investigated long-term survival and analyzed radiological modes of failure. Pati

Creating creative environments

There is empirical evidence indicating that trust in research is decreasing. If distrust is justified, this is a good thing; if not, it is a cause of concern. A basic question concerns the reasons for, ant the causes of, distrust. Which are they, what do they mean, and how reliable are they? The papers and presentations in this volume focus on external and internal factors contributing to distrus

On the sensitivity of rotational CARS N-2 thermometry to the Herman-Wallis factor

Purely rotational spectral signals of coherent anti-Stokes Raman scattering (CARS) from nitrogen molecules are studied as a function of the vibration-rotation interaction that weakens the rigid rotor approximation under which the dominant terms of the Raman cross section are calculated. The effect of the vibration-rotation interaction is quantified by means of the Herman-Wallis (HW) factor, and di

The impact of cow's milk-mediated mTORC1-signaling in the initiation and progression of prostate cancer

Prostate cancer (PCa) is dependent on androgen receptor signaling and aberrations of the PI3K-Akt-mTORC1 pathway mediating excessive and sustained growth signaling. The nutrient-sensitive kinase mTORC1 is upregulated in nearly 100% of advanced human PCas. Oncogenic mTORC1 signaling activates key subsets of mRNAs that cooperate in distinct steps of PCa initiation and progression. Epidemiological ev

Tuberculosis burden in an urban population: a cross sectional tuberculosis survey from Guinea Bissau

Background: Little is known about the prevalence of pulmonary tuberculosis (TB) in low income countries. We conducted a cross sectional survey for pulmonary TB and TB symptoms in Bissau, Guinea-Bissau, in an urban cohort with known HIV prevalence. TB surveillance in the area is routinely based on passive case finding. Methods: Two cohorts were selected based on a previous HIV survey, but only 52.5

Population-based consultation patterns in patients with shoulder pain diagnoses

Background: To assess the annual consultation prevalence and new onset consultation rate for doctor-diagnosed shoulder pain conditions. Methods: We identified all residents in the southernmost county in Sweden who received a shoulder pain diagnosis during 2006 (ICD-10 code M75). In subjects who did not consult due to such disorders during 2004 and 2005, we estimated the new onset consultation rate

Traffic pollution and chronic respiratory disease. Epidemiological studies in children and adults in southern Sweden.

This thesis investigate if long-term exposure to traffic pollution is a risk factor for development of chronic respiratory disease and allergy in adults and children in southern Sweden (Scania). Information about health was obtained from surveys and health care registers. Traffic pollution exposure was estimated by traffic intensity and levels of NOx at residential addresses, which were obtained

Severe Streptococcus pyogenes disease in Europe; epidemiology and clinical manifestations

Streptococcus pyogenes, gives rise from mild skin infections and pharyngitis, to life threatening infections like bacteraemia, cellulitis, puerperal sepsis, meningitis, pneumonia, necrotizing fasciitis (NF), and streptococcal toxic-like shock syndrome (STSS), or nonsuppurative sequelae, rheumatic fever and glomerulonephritis. In 2002, the first multinational network for invasive GAS disease survei