Search results

Filter

Filetype

Your search for "*" yielded 532033 hits

Supporting e-learning : an overview of the needs of users

It has become banal to refer to the growth in the use of the Internet in Higher Education (HE). It is now time to regard ‘e-learning’ as an integral part of academic activity, which needs to be routinely supported. This article provides an overview of what is happening and makes some suggestions for organising support services for e-learning.

Accreditation! the responsive curriculum game

It can be difficult to engage colleagues with the findings and recommendations of an externally-funded project, even when, or perhaps particularly when, it has major implications for institutional processes. The authors were involved with a large single-institution Higher Education change project that aimed to make the university more responsive to changes in curriculum needs, the student voice, e

Nehari's Theorem for Convex Domain Hankel and Toeplitz Operators in Several Variables

We prove Nehari s theorem for integral Hankel and Toeplitz operators on simple convex polytopes in several variables. A special case of the theorem, generalizing the boundedness criterion of the Hankel and Toeplitz operators on the Paley Wiener space, reads as follows. Let = (0, 1)d be a d-dimensional cube, and for a distribution f on 2, consider the Hankel operator f (g)(x) = λ f (x + y)g(y) dy,

40Ar/39Ar age evidence for an impact-generated hydrothermal system in the Devonian Siljan crater, Sweden

Crater-forming events are generally followed by the development of hydrothermal systems due to the rapid heating of the target rock. Such hydrothermal systems are a feature of nearly all large terrestrial impact structures. For the Siljan impact structure in Sweden, there is evidence for such a fossil hydrothermal system, possibly triggered by the impact event ca. 380 Ma. To investigate the therma

Applications of phytochemicals against nerve agents in counterterrorism

Terrorism comes in various forms, clear and sometimes ambiguous, by terrorist cells and sometimes by state players. Nerve agent poisoning represents one of the notorious applications of chemistry in the world. Nerve agents have historically instigated major casualties in various parts, heavily impacting lives of civilians by causing debilitating neurological and psychiatric injuries. Nerve agents

Petrochemicals and Climate Change : Tracing Globally Growing Emissions and Key Blind Spots in a Fossil-Based Industry

With the risk of climate breakdown becoming ever more pressing as the world is on track for 2.7 degrees warming, pressure is increasing on all sectors of the economy to break with fossil fuel dependence and reduce greenhouse gas (GHG) emissions. In this context, the chemical industry and the production of important basic chemicals is a key sector to consider. Although historically a driver of econ

Interventions for the management of transient tachypnoea of the newborn - an overview of systematic reviews

Background: Transient tachypnoea of the newborn (TTN) is characterised by tachypnoea and signs of respiratory distress. It is caused by delayed clearance of lung fluid at birth. TTN typically appears within the first two hours of life in term and late preterm newborns. Although it is usually a self-limited condition, admission to a neonatal unit is frequently required for monitoring, the provision

Solubility of Aβ40 peptide

In this work we measured, by using a direct approach, the equilibrium solubility of recombinant Aβ40 peptide to be S ​= ​0.36 ​± ​0.15 ​μM in aqueous solution of 20 ​mM sodium phosphate buffer at pH 7.4. Microfluidic diffusional sizing (MDS) and mass spectrometry (MALDI-TOF/TOF) with isotope standard were used to quantify the concentration of soluble Aβ40 species coexisting with formed fibrils. A

The influence of maternal glucocorticoids on offspring phenotype in high-and low-risk environments

Elevated maternal glucocorticoid levels during gestation can lead to phenotypic changes in offspring via maternal effects. Although such effects have traditionally been considered maladaptive, maternally derived glucocorticoids may adaptively prepare offspring for their future environment depending upon the correlation between maternal and offspring environments. Nevertheless, relatively few studi

Pharmacoepigenetics in type 2 diabetes : is it clinically relevant?

Data generated over nearly two decades clearly demonstrate the importance of epigenetic modifications and mechanisms in the pathogenesis of type 2 diabetes. However, the role of pharmacoepigenetics in type 2 diabetes is less well established. The field of pharmacoepigenetics covers epigenetic biomarkers that predict response to therapy, therapy-induced epigenetic alterations as well as epigenetic

Body mass dynamics of migratory nightjars are explained by individual turnover and fueling

Body mass is a commonly used indicator of the energy stores of migratory animals and there is considerable evidence that it is a critical determinant of migration decisions and outcomes. Mean population mass often increases during the post-breeding period in most migratory species. Usually, this increase is interpreted as the result of fuel accumulation for migration based on the assumption that m

Inventory Policies Under Service Level Target : Comparison in Terms of Relevant Costs and Bullwhip Effect

Global shifts in technology and demand patterns might necessitate a firm’s switching to another inventory management system. The following five popular types of inventory policies are compared in terms of their impact on relevant inventory costs and bullwhip effect: newsvendor, order-up-to, min-max, reorder-point order-quantity, and economic order quantity. The model of four-stage supply chain pre

Physical retailing vs. physical distancing–an empirical study of Swedish retail adaptations in the wake of Covid-19

The Covid-19 pandemic represented a crisis that was handled in very different ways by different retailers. The purpose of this comprehensive empirical study is to explore how Swedish retailers adapted their retail formats, activities and governance over the course of the pandemic. Three types of adaptations were observed: adaptations in the physical store environment, new services connected to the

A pro-2 group with full normal Hausdorff spectra

We construct a 2-generated pro-2 group with full normal Hausdorff spectrum [0, 1] [0,1], with respect to each of the four standard filtration series: the 2-power series, the lower 2-series, the Frattini series, and the dimension subgroup series. This answers a question of Klopsch and the second author, for the even prime case; the odd prime case was settled by the first author and Klopsch. Also, o

Dietary Supplements and Nutraceuticals under Investigation for COVID-19 Prevention and Treatment

Coronavirus disease 2019 (COVID-19) has caused global disruption and a significant loss of life. Existing treatments that can be repurposed as prophylactic and therapeutic agents may reduce the pandemic’s devastation. Emerging evidence of potential applications in other therapeutic contexts has led to the investigation of dietary supplements and nutraceuticals for COVID-19. Such products include v

Probing and improving coherence in Free-electron lasers

Free electron lasers or FELs, have transformed the way science has been done in the last decades by providing coherent, highly brilliant radiation at wavelengths not achievable with conventional lasers. Their most important characteristic, along side brightness, is their coherence, which allows users to perform experiments that rely on precise phase characteristics of the probing radiation.The FEL

Single-shot transverse coherence in seeded and unseeded free-electron lasers: A comparison

The advent of x-ray free-electron lasers (FELs) drastically enhanced the capabilities of several analytical techniques, for which the degree of transverse (spatial) coherence of the source is essential. FELs can be operated in self-amplified spontaneous emission (SASE) or seeded configurations, which rely on a qualitatively different initialization of the amplification process leading to light emi

Binary separation control in preparative gradient chromatography using iterative learning control

Purification of biopharmaceuticals has shifted toward continuous and integrated processes, in turn bringing along a need for monitoring and control to maintain a desired separation between the target pharmaceutical and any impurities it may carry. In this study, a cycle-to-cycle control of the retention volumes of two compounds in a chromatographic, ion exchange purification step was developed, al