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To Drink Bull´s Blood : An analysis of the Story of Midas

This paper deals with the famous account of how Midas committed suicide by drinking bull’s blood. There was a widespread ancient belief that you would die from consuming the blood of a bull, but from a medical point of view it is not poisonous to drink bull’s blood. This paper has its point of departure in this erroneous ancient perception, and analyses what may lay behind the idea that Midas as w

C4BP-IgM protein as a therapeutic approach to treat Neisseria gonorrhoeae infections

Gonorrhea is a sexually transmitted infection with 87 million new cases per year globally. Increasing antibiotic resistance has severely limited treatment options. A mechanism that Neisseria gonorrhoeae uses to evade complement attack is binding of the complement inhibitor C4b-binding protein (C4BP). We screened 107 porin B1a (PorB1a) and 83 PorB1b clinical isolates randomly selected from a Swedis

RTNduals an R/Bioconductor package for analysis of co-regulation and inference of dual regulons

MOTIVATION: Transcription factors (TFs) are key regulators of gene expression, and can activate or repress multiple target genes, forming regulatory units, or regulons. Understanding downstream effects of these regulators includes evaluating how TFs cooperate or compete within regulatory networks. Here we present RTNduals, an R/Bioconductor package that implements a general method for analyzing pa

The Historical Geography of Phrygia : The Settlement of Leonton Kephalai

This article examines the literary evidence for a settlement in Phrygia named Leonton Kephalai, i.e. Lions´Heads. According to preserved literary sources, of which there are only three, Leonton Kephalai was an important military stronghold from the Achaemenid period until the end of the Roman Republic, but the settlement may have been occupied for longer. Furthermore, one literary source specifial

En finanspolitisk union för euron: lärdomar från federala stater

Denna rapport kartlägger vilken form av finanspolitiskt ramverk som bäst kan undvika de mekanis- mer som idag hotar den finansiella stabiliteten i euroområdet. Diskussionen bygger på en gransk- ning av de fiskala relationerna mellan den federala och delstatliga nivån i fyra federala stater: Argentina, Brasilien, Kanada och USA. En jämförelse mellan de fyra staterna visar på en tydlig skillnad. De

Age at first childbirth and breast cancer survival : A prospective cohort study

Objective: Late age at first childbirth is a well-established risk factor for breast cancer. Previous studies have, however, shown conflicting results to whether late age at first childbirth also influences the prognosis of breast cancer survival. The aim of this study was to examine age at first birth in relation to survival after breast cancer diagnosis. Results: We used information from the Mal

Education for sustainability : Fostering a more conscious society and transformation towards sustainability

Purpose: Current approaches to sustainability science and education focus on (assessing and addressing) the external world of ecosystems, wider socio-economic structures, technology and governance dynamics. A major shortcoming of such approaches is the neglect of inner dimensions and capacities (which constrains education for sustainability as an end), and a limited capacity to facilitate reflecti

Socioeconomic status of patients in a Swedish national self-management program for osteoarthritis compared with the general population - A descriptive observational study

Background: First-line treatment for hip and knee osteoarthritis (OA) including education and supervised exercises, delivered as a self-management program, is considered one of the mainstays in OA treatment. However, the socioeconomic profile of the population that utilizes first-line treatment for hip and knee OA is unclear. The aim of this study was to describe the socioeconomic status (SES) of

Oral Contraceptive Use and Breast Cancer Risk : Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study

Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive preparation (OCP) use and breast cancer (BC) risk is still unclear.Methods: Breast camcer risk associations were estimated from OCP data on 6030 BRCA1 and 3809 BRCA2 mutation carriers using age-dependent Cox regression, stratified by study and birth cohort. Prospective, left-truncated retrospective and fu

Validation of the Strengths and Difficulties Self-Report in Norwegian Sign Language

The majority of studies on mental health in deaf and hard-of-hearing (DHH) children report a higher level of mental health problems. Inconsistencies in reports of prevalence of mental health problems have been found to be related to a number of factors such as language skills, cognitive ability, heterogeneous samples as well as validity problems caused by using written measures designed for typica