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The algebraic regulator problem is formulated and solved in a transfer matrix setting. It is shown that, provided the closed loop system disregarding disturbances is stable, a necessary and sufficient condition for output regulation to take place is that the open loop path consisting of the plant and compensator in cascade, contains a suitably defined internal model of the environment. The disturb
The vitamin D receptor (VDR) has been proposed as a candidate gene for several musculoskeletal phenotypes. However, previous results on the associations between genetic variants of the VDR with muscle strength and falls have been contradictory. The MrOS Sweden survey, a prospective population-based cohort study of 3014 elderly men (mean age 75 years, range 69–81) offered the opportunity to further
In this paper we study coupled dynamical systems and investigate dimension properties of the subspace spanned by solutions of each individual system. Relevant problems on collinear dynamical systems and their variations are discussed recently by Montenbruck et. al. in [1], while in this paper we aim to provide a unified analysis to derive the dimensional-invariance principles for networked coupled
During development, hematopoietic stem and progenitor cells (HSPCs) arise from specialized endothelial cells by a process termed endothelial-to-hematopoietic transition (EHT). The genetic program driving human HSPC emergence remains largely unknown. We previously reported that the generation of hemogenic precursor cells from mouse fibroblasts recapitulates developmental hematopoiesis. Here, we dem
Nanowires offer remarkable opportunities for realizing new optoelectronic devices because of their unique fundamental properties. The ability to engineer nanowire heterostructures with large bandgap variations is particularly interesting for technologically important broadband photodetector applications. Here we report on infrared photodetectors based on arrays of InP nanowires with embedded InAsP
While the contemporary academic discourse regards innovation as an inherent feature of infrastructure public‒private partnerships (PPPs), the conceptual link between infrastructure PPPs and innovation is narrowly understood. While most existing studies conceptualize the innovation processes and effects within the context of PPP projects, we argue that the relevance of innovation in infrastructure
Many migratory species have experienced substantial declines that resulted from rapid and massive expansions of human structures and activities, habitat alterations and climate change. Migrants are also recognized as an integral component of biodiversity and provide a multitude of services and disservices that are relevant to human agriculture, economy and health. The plethora of recently publishe
Introduction: Previous studies have shown that the injection of adipose tissue–derived stem cells (ADSCs) into the tunica albuginea (TA) during the active phase of Peyronie's disease (PD) prevents the development of fibrosis. Aim: To investigate, using an animal model, whether local injection of human ADSCs (hADSCs) can alter the degree of fibrosis in the chronic phase of PD. Methods: 27 male, 12-
A new method of model reduction is introduced based on the differentiation of polynomials. The reciprocals of the numerator and denominator polynomials of the high-order transfer function are differentiated suitably many times to yield the coefficients of the reduced order transfer function. An error analysis shows the accuracy of the method, and an eighth-order example illustrates it. The method
