AIM OF THE STUDY: to investigate the incidence of non-mapped isolated metastatic pelvic lymph nodes at pre-defined anatomical positions.PATIENTS AND METHODS: Between June 2019 and January 2024, women with uterine-confined endometrial cancer (EC) deemed suitable for robotic surgery and the detection of pelvic sentinel nodes (SLNs) were included. An anatomically based, published algorithm utilizing

Quantification of face-to-face interaction can provide highly relevant information in cognitive and psychological science research. Current commercial glint-dependent solutions suffer from several disadvantages and limitations when applied in face-to-face interaction, including data loss, parallax errors, the inconvenience and distracting effect of wearables, and/or the need for several cameras to

Neuropsychiatric and neurodevelopmental disorders are often associated with coordination problems. Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) constitutes a specific example of acute and complex symptomatology that includes difficulties with motor control. The present proof-of-concept study aimed at testing a new, bespoke tablet-based motor coordination test named SpaceSwipe, providing

Pupillary contagion occurs when one's pupil size unconsciously adapts to the pupil size of an observed individual and is presumed to reflect the transfer of arousal. Importantly, when estimating pupil contagion, low level stimuli properties need to be controlled for, to ensure that observations of pupillary changes are due to internal change in arousal rather than the external differences between

Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T

Dynamic polyimine-amide networks with exceptional properties, including high flexibility, excellent thermal stability and dual closed-loop circularity were designed by combining dynamic covalent imine-functionalities with amide-chemistry. The solvent free up-scalable synthesis started from carboxyl-functionalization of lignin-derivable aldehydes followed by melt polycondensation with a triamine to

DNA-encoded chemical libraries are increasingly used in pharmaceutical research because they enable the rapid discovery of synthetic protein ligands. Here we explored whether target-class focused DNA-encoded chemical libraries can be cost-effective tools to achieve robust screening productivity for a series of proteins. The study revealed that a DNA-encoded library designed for NAD+-binding pocket

This comparative study delves into the intricate challenges surrounding stigma within active labor market programs (ALMPs) and its implications for work, wellbeing, and social policy. In both Sweden and Australia, employers exhibit reluctance to draw from this candidate pool for recruitment. Understanding employers' reasons for not utilising ALMP candidates, their expectations from candidates, and

Trading commodities has been around for centuries, and today, most trading is done electronically on exchanges in derivatives contracts. Over time, regulatory bodies, specifically the CFTC, have sought to implement safeguards against market manipulation by participants. One such measure has been position limits on derivatives, which since January 1st, 2023, also includes so-called economically equ

This thesis explores the Point-in-Time (PIT) in probability of default (PD) models, focusing on evaluating the degree of PIT-ness. Unlike previous studies that developed new measures for PIT characteristics, this research compares existing measures and frameworks to identify unique challenges and opportunities. By analyzing and testing existing measures for 1-year PD models, the study offers new i

Hamilton’s rule provides the cornerstone for our understanding of the evolution of all forms of social behavior, from altruism to spite, across all organisms, from viruses to humans. In contrast to the standard prediction from Hamilton’s rule, recent studies have suggested that altruistic helping can be favored even if it does not benefit relatives, as long as it decreases the environmentally indu

Peptihub (https://bioinformaticscollege.ir/peptihub/) is a meticulously curated repository of cancer-related peptides (CRPs) that have been documented in scientific literature. A diverse collection of CRPs is included in the PeptiHub, showcasing a spectrum of effects and activities. While some peptides demonstrated significant anticancer efficacy, others exhibited no discernible impact, and some e

Warm Jupiters are ideal laboratories for testing the limitations of current tools for atmospheric studies. The cross-correlation technique is a commonly used method to investigate the atmospheres of close-in planets, leveraging their large orbital velocities to separate the spectrum of the planet from that of the star. Warm Jupiter atmospheres predominantly consist of molecular species, notably wa

In-store smart technology is rapidly transforming service delivery and value creation in the retail sector. However, despite these advances, academic acumen of customers' perceived value of their smart service interactions remains tenuous, exposing an important omission in extant literature. Addressing this gap, we conceptualize, operationalize, and validate smart service value (SSV) in the retail

The first mass-distributed vaccines based on mRNA technology were launched in 2021 to protect against COVID-19, sparking rumours among vaccine critical individuals that these “new” vaccines might be more dangerous to the health than other, “traditional” vaccines. Drawing on rumour theories and social cognitive perspectives, the aim of this chapter is to account for the purpose and the spreading of

Many performance sport passenger vehicles use drilled or grooved cast iron brake rotors for a better braking performance or a cosmetic reason. Such brake rotors would unfortunately cause more brake dust emission, appearing with dirty wheel rims. To better understand the effects of such brake rotors on particle emission, a pin-on-disc tribometer with two particle emission measurement devices was us

Elevated levels of glial fibrillary acidic protein (GFAP) in plasma reflect neuroinflammation and are linked to cognitive decline. Preclinical studies show that dietary change can attenuate astrocyte reactivity and neuroinflammation. In the current study, we investigate if the Okinawa-based Nordic (O-BN) diet alters plasma GFAP levels in patients with Type 2 Diabetes (T2D), a metabolic disorder as

Objective: The objective of this study was to study the recovery from, and incidence of, work-restricting musculoskeletal pain after bariatric surgery compared with usual obesity care. Methods: Pain in different body regions was monitored using questionnaires in the nonrandomized, prospective, controlled Swedish Obese Subjects (SOS) study, which included 2007 participants treated with bariatric su