Search results

Filter

Filetype

Your search for "*" yielded 528606 hits

Circulatory insulin-like growth factor-I and brain volumes in relation to neurodevelopmental outcome in very preterm infants.

Background:To evaluate the relationships between postnatal change in circulatory insulin-like growth factor I (IGF-I) concentrations, brain volumes, and developmental outcome at 2 years of age in very preterm infants.Methods:IGF-I was measured weekly and nutritional intake was calculated daily from birth until a postmenstrual age (PMA) of 35 weeks. Individual beta coefficients for IGF-I, IGF-I(B)

Exploring different cationic alkyl side chain designs for enhanced alkaline stability and hydroxide ion conductivity of anion-exchange membranes

In order to systematically improve the performance of anion-exchange membranes (AEMs) for alkaline fuel cells, a series of poly(phenylene oxide)s (PPOs) was tethered with cationic alkyl side chains of different lengths and configurations. PPO was first functionalized with bromomethyl and longer bromoalkyl side chains, respectively, before introducing quaternary ammonium (QA) groups via Menshutkin

The effect of high temperatures on seed germination of one native and two introduced conifers in Patagonia

We examined the effect of thermal shock on the germination of seeds of three conifers, two introduced (Pseudotsuga menziesii and Pinus ponderosa), and one native to Patagonia (Araucaria araucana). Previous research has suggested increased susceptibility to invasions in burnt areas, and therefore, the effect of simulated fire (heat) on seed germination in these native and introduced species was com

The Arctic Summer Cloud Ocean Study (ASCOS): overview and experimental design

The climate in the Arctic is changing faster than anywhere else on earth. Poorly understood feedback processes relating to Arctic clouds and aerosol-cloud interactions contribute to a poor understanding of the present changes in the Arctic climate system, and also to a large spread in projections of future climate in the Arctic. The problem is exacerbated by the paucity of research-quality observa

Mary Wollstonecraft’s Feminist Critique of Property. On Becoming a Thief From Principle

The scholarship on Mary Wollstonecraft (1759-1797) is divided concerning her views on women’s role in public life, property rights and distribution of wealth. Her critique of inequality of wealth is undisputed, but is it a complaint only of inequality or does it strike more forcefully at the institution of property? The argument in this article is that Wollstonecraft’s feminism is partly defined b

Precision measurement of the mass difference between light nuclei and anti-nuclei

The measurement of the mass differences for systems bound by the strong force has reached a very high precision with protons and anti-protons(1,2). The extension of such measurement from (anti-)baryons to (anti-) nuclei allows one to probe any difference in the interactions between nucleons and anti-nucleons encoded in the (anti-) nuclei masses. This force is a remnant of the underlying strong int

A recent growth increase of European beech (Fagus sylvatica L.) at its Mediterranean distribution limit contradicts drought stress

Future changes in tree growth, associated with a warmer and drier climate, are predicted for many species and locations across the European Mediterranean Basin. However, quantification of the intensity and severity of related consequences for forest ecosystem functioning and productivity remains challenging. Species-specific distribution limits that are particularly sensitive to small changes in t

Role of SRC-like adaptor protein (SLAP) in immune and malignant cell signaling.

SRC-like adaptor protein (SLAP) is an adaptor protein structurally similar to the SRC family protein kinases. Like SRC, SLAP contains an SH3 domain followed by an SH2 domain but the kinase domain has been replaced by a unique C-terminal region. SLAP is expressed in a variety of cell types. Current studies suggest that it regulates signaling of various cell surface receptors including the B cell re

Submicroscopic genomic imbalances in burkitt lymphomas/leukemias: Association with age and further evidence that 8q24/MYC translocations are not sufficient for leukemogenesis.

Chromosome banding analyses reveal secondary chromosome abnormalities in addition to the MYC translocations t(8;14)(q24;q32), t(8;22)(q24;q11), and t(2;8)(p11;q24) in 60%-80% of Burkitt lymphomas/leukemias (BL). The high incidence of such aberrations indicates that additional changes are important, perhaps necessary, for malignant transformation, i.e., the 8q24/MYC rearrangements may not be suffic

Cross-Reactive Protection against Enterohemorrhagic Escherichia coli Infection by Enteropathogenic Escherichia coli in a Mouse Model.

Enteropathogenic (EPEC) and enterohemorrhagic (EHEC) Escherichia coli are related attaching and effacing (A/E) pathogens. The genes responsible for the A/E pathology are encoded in a chromosomal pathogenicity island termed the locus of enterocyte effacement (LEE). Both pathogens share a high degree of homology in the LEE and additional 'O' islands. EHEC prevalence is much lower in EPEC endemic are

Identification of Individualized Empirical Models of Carbohydrate and Insulin Effects on T1DM Blood Glucose Dynamics

One of the main limiting factors in improving glucose control for type 1 diabetes mellitus (T1DM) subjects is the lack of a precise description of meal and insulin intake effects on blood glucose. Knowing the magnitude and duration of such effects would be useful not only for patients and physicians, but also for the development of a controller targeting glycaemia regulation. Therefore, in this pa

Gasoline partially premixed combustion: high efficiency, low NOx and low soot by using an advanced combustion strategy and a compression ignition engine

A light-duty engine Volvo D5 was run with gasoline to demonstrate that high-octane number fuels, in compression ignition engines, are able to achieve high efficiency, low NOx and soot simultaneously. An advanced three stage injection strategy was developed. A load sweep was performed between 6 and 17 bar IMEP and 2000 rpm. Gross indicated efficiency stays fairly constant at 47% with very low NOx a

Labour Market Externalities and Regional Growth in Sweden: The Importance of Labour Mobility between Skill-Related Industries

Regional Studies. This study investigates the relationship between labour market externalities and regional growth based on real labour flows. In particular, it tests for the importance of labour mobility across so-called skill-related industries between 435 four-digit industries within 72 Swedish functional regions (1998-2002). Both the fixed-effect models and generalized method of moments (GMM)

The stage-value model: Implications for the changing standards of care.

The standard of care is a legal and professional notion against which doctors and other medical personnel are held liable. The standard of care changes as new scientific findings and technological innovations within medicine, pharmacology, nursing and public health are developed and adopted. This study consists of four parts. Part 1 describes the problem and gives concrete examples of its occurren

A probabilistic fracture mechanics method and strength analysis of glulam beams with holes

A probabilistic fracture mechanics method is presented and applied to glulam beams with holes. The method is based on a combination of Weibull weakest link theory and a mean stress method which is a generalization of linear elastic fracture mechanics. Combining these two methods means that the global strength will be governed by both fracture energy and material strength and also that the stochast

Comparison of the active-site design of molybdenum oxo-transfer enzymes by quantum mechanical calculations.

There are three families of mononuclear molybdenum enzymes that catalyze oxygen atom transfer (OAT) reactions, named after a typical example from each family, viz., dimethyl sulfoxide reductase (DMSOR), sulfite oxidase (SO), and xanthine oxidase (XO). These families differ in the construction of their active sites, with two molybdopterin groups in the DMSOR family, two oxy groups in the SO family,