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Methotrexate Treatment Suppresses Monocytes in Nonresponders to Pneumococcal Conjugate Vaccine in Rheumatoid Arthritis Patients

Patients with rheumatoid arthritis (RA) have an increased risk of infections; therefore, immunization against vaccine-preventable diseases is important. Methotrexate (MTX) impairs the antibody response to pneumococcal conjugate vaccine (PCV) in patients with arthritis, and the underlying mechanism is largely unknown. Here, we investigate the potential role of the innate immune system in the falter

Sensitivity of Diffusion MRI to White Matter Pathology : Influence of Diffusion Protocol, Magnetic Field Strength, and Processing Pipeline in Systemic Lupus Erythematosus

There are many ways to acquire and process diffusion MRI (dMRI) data for group studies, but it is unknown which maximizes the sensitivity to white matter (WM) pathology. Inspired by this question, we analyzed data acquired for diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) at 3T (3T-DTI and 3T-DKI) and DTI at 7T in patients with systemic lupus erythematosus (SLE) and healthy c

Resonant Frequency Ultrasonic P-Waves for Evaluating Uniaxial Compressive Strength of the Stabilized Slag–Cement Sediments

Marina sediment kan stabiliseras med ultrahöghållfasta bindemedel: cement, Cement Kiln Dust (CKD) och slagg. Egenskaperna hos den stabiliserade jorden indikerar potential för återanvändning. Den här studien undersökte prestandan för den enaxiella tryckhållfastheten (UCS) i smarina sediment stabiliserade med bindemedel (cement, CKD, slagg), testade med ultraljuds P-vågor. Material omfattar 194 prov

Habitat selection and foraging site fidelity in Caspian Terns (Hydroprogne caspia) breeding in the Baltic Sea

Habitat preferences and foraging strategies affect population-level space use and are therefore crucial to understanding population change and implementing spatial conservation and management actions. We investigated the breeding season habitat preference and foraging site fidelity of the under-studied and threatened, Baltic Sea population of Caspian Terns (Hydroprogne caspia). Using GPS devices,

Introduction of e-portfolio – what do we know?

Aims and ObjectivesTo explore experiences and perceptions from teachers’ and students’ regarding the use of e-portfolio/portfolio through a literature review.Materials and methodsA meta ethnographic literature review was conducted following the guidelines (1). From 94 hits, seven papers fit the criteria for further analysis and synthesis.Search terms: portfolio AND dental AND educationResultsTwo m

Creating a system for Quality and Progress – The Purposeful Need for Technology?

The use of a learning management/assessment system has become common in higher education during the past 20 years. However, such systems are frequently not grounded in approaches to support longitudinal educational needs, such as promoting professional development. One reason may be that digital support is designed to assist with isolated tasks e.g. running MCQ tests, and therefore is not develope

Direct and indirect pressures of climate change on nutrient and carbon cycling in northern forest ecosystems : Dynamic modelling for policy support

Northern forest ecosystems play an important role in mitigating climate change by sequestrating carbon (C), while additionally providing and regulating other ecosystem services. A majority of the Swedish environmental quality objects (EQOs) that guide Swedish environmental policy and management are associated with the forest, and they have proven difficult to achieve. Several of them relate to the

Rectification from radially-distorted scales

This paper introduces the first minimal solvers that jointly estimate lens distortion and affine rectification from repetitions of rigidly-transformed coplanar local features. The proposed solvers incorporate lens distortion into the camera model and extend accurate rectification to wide-angle images that contain nearly any type of coplanar repeated content. We demonstrate a principled approach to

Minimal solvers for rectifying from radially-distorted scales and change of scales

This paper introduces the first minimal solvers that jointly estimate lens distortion and affine rectification from the image of rigidly-transformed coplanar features. The solvers work on scenes without straight lines and, in general, relax strong assumptions about scene content made by the state of the art. The proposed solvers use the affine invariant that coplanar repeats have the same scale in

Deep shutter unrolling network

We present a novel network for rolling shutter effect correction. Our network takes two consecutive rolling shutter images and estimates the corresponding global shutter image of the latest frame. The dense displacement field from a rolling shutter image to its corresponding global shutter image is estimated via a motion estimation network. The learned feature representation of a rolling shutter i

From two rolling shutters to one global shutter

Most consumer cameras are equipped with electronic rolling shutter, leading to image distortions when the camera moves during image capture. We explore a surprisingly simple camera configuration that makes it possible to undo the rolling shutter distortion: two cameras mounted to have different rolling shutter directions. Such a setup is easy and cheap to build and it possesses the geometric const

The european union in international relations : Great power under strain?

This chapter focuses on the diplomatic, security, and defence dimensions of EU foreign policy. Developments in the last decade, not least Russia's annexation of Crimea, China's increasing global political - and not only economic - prevalence, and America's reoriented foreign policy all speak to this dynamic - and also render the EU a more challenging position in international relations. Recognitio

Theorising diplomacy

This chapter reviews the most important beginning with the long tradition of prescriptive tracts, offering observations and advice concerning the conduct of diplomacy. Authors from du Rosier to Nicolson were practitioners, who not only aimed at describing and explaining diplomacy but also had a clear prescriptive bent, offering recommendations as to the best conduct of diplomacy. War and military

Long-term anti-tumor effects following both conventional radiotherapy and FLASH in fully immunocompetent animals with glioblastoma

Radiotherapy can induce an immunological response. One limiting factor is side effects on normal tissue. Using FLASH radiotherapy, side effects could possibly be reduced. The efficacy of FLASH in relation to conventional radiotherapy (CONV-RT) has not been extensively explored in fully immunocompetent animals. Fully immunocompetent Fischer 344 rats were inoculated with NS1 glioblastoma cells subcu

Treatment Strategies and Risk of Recurrence in Patients with Heart Valve Prosthesis, Staphylococcus aureus Bacteremia, and Possible Endocarditis - A Retrospective Cohort Study

Patients with heart valve prosthesis (HVP) and Staphylococcus aureus bacteremia (SAB) are at risk for endocarditis. In this retrospective, population-based cohort study of 134 patients with SAB and HVP, 97 patients (72%) were diagnosed with possible endocarditis. Despite that most patients with possible endocarditis received short antibiotic treatment, only 3 patients suffered recurrent SAB.