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Postprandial Glucagon Reductions Correlate to Reductions in Postprandial Glucose and Glycated Hemoglobin with Lixisenatide Treatment in Type 2 Diabetes Mellitus : A Post Hoc Analysis

Introduction: The extent to which postprandial glucagon reductions contribute to lowering of postprandial glucose in patients with type 2 diabetes mellitus (T2DM) is currently unknown. The aim of this analysis was to determine whether a reduction in postprandial glucagon following treatment with the glucagon-like peptide-1 receptor agonist lixisenatide correlates with a reduction in postprandial g

Burden of Diarrhea in the Eastern Mediterranean Region, 1990-2013 : Findings from the Global Burden of Disease Study 2013

Diarrheal diseases (DD) are leading causes of disease burden, death, and disability, especially in children in low-income settings. DD can also impact a child's potential livelihood through stunted physical growth, cognitive impairment, and other sequelae. As part of the Global Burden of Disease Study, we estimated DD burden, and the burden attributable to specific risk factors and particular etio

Phenotypic map of porcine retinal ganglion cells

PURPOSE: Porcine retina is an excellent model for studying diverse retinal processes and diseases. The morphologies of porcine retinal ganglion cells (RGCs) have, however, not yet been described comprehensively. The aim of the present study was to créate a classification of the RGCs using the 1, 1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiI) tracing method.METHODS: About 17

Humlesugan i Skåne och Danmark under 500 år

Humlesugan, Betonica officinalis L., är en avden skandinaviska florans sällsyntaste växteroch samtidigt en av de arter som har denlängsta dokumenterade historien. Den rapporteradesfrån Stehag väster om Ringsjön i Skåneav Christiern Pedersen redan 1534, Skånesäldsta litteraturuppgift där en växtart knytstill en lokal. I övriga Danmark beskrevs denmed lokaluppgift första gången av Peder LauridsenKyl

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The Marquis de Condorcets "Esquisse d'un Tableau Historique des Progres de l'Esprit Humain" was one of the first books by Klaus Henrik Seidelin translated into Danish and published in Copenhagen in 1797. The chapter examines how Seidelin worked as a writer, translator and printer in Copenhagen. What were the conditions like for freedom of the press in 1797? How did Seidelin interpret the Enlighten

Satellite tracking of Bean Geese Anser fabalis fabalis and A. f. rossicus from spring staging areas in northern Sweden to breeding and moulting areas.

In order to determine their breeding and moulting siteswe fitted eight Taiga Bean Geese Anser fabalis fabalisand two Tundra Bean Geese A. f. rossicus with satellitetransmitters in 2007–2009 at their spring roosting sitesat Umeå and Luleå, Sweden. Nine of these transmitterstransferred GPS positions for 1–4 months. All positionswere N–ENE of the catching sites. The Tundra BeanGeese migrated to Finnm

Changes of numbers and distribution of wintering waterfowl in Sweden during forty years, 1967 - 2006.

Regular midwinter counts of waterfowl (included in theInternational Midwinter Counts, IWC, organized by whatis now Wetlands International) has been undertaken inSweden since the start in 1967 and are still going on,now as a part of the National Environmental MonitoringProgramme. After the first exploratory years includingcountry-wide surveys in 1971–1973 undertaken bothfrom the ground, the air and

A strong visible line in the spectrum of W11+

We have investigated the visible spectrum of W11+ and found a very strong line at the wave length of 527.61 nm from the 4f135s25p2 (2F7/2-2F5/2) transition. We show that this line is strong since the excitation energy of the upper level opens up the possibility to capture a large population. We discuss the possibility that this strong line could be the unknown line seen in charge exchange spectra

Prevalence and Prognostic Implications of Bundle Branch Block in Comatose Survivors of Out-of-Hospital Cardiac Arrest

This study reports the prevalence and prognostic impact of right bundle branch block (RBBB) and left bundle branch block (LBBB) in the admission electrocardiogram (ECG) of comatose survivors of out-of-hospital cardiac arrest (OHCA). The present study is part of the predefined electrocardiographic substudy of the prospective randomized target temperature management trial, which found no benefit of

Benchmarking Geant4 for spallation neutron source calculations

Geant4 is becoming increasingly used for radiation transport simulations of spallation neutron sources and related components. Historically, the code has seen little usage in this field and it is of general interest to investigate the suitability of Geant4 for such applications. For this purpose, we carried out Geant4 calculations based on simple spallation source geometries and also with the the

The Subject in International Law : The Administrator of the Coalition Provisional Authority of Occupied Iraq and its Laws

In the wake of the war and occupation of Iraq, 2003–2004, international legal scholars struggled to understand and adequately describe the event and the law surrounding it. This study takes that situation of uncertainty as its point of departure, and it unfolds through an analysis of the material conditions and linguistic–rhetoric and affective–psychic registers through which the Administrator of In the wake of the war and occupation of Iraq, 2003–2004, international legal scholars struggled to understand and adequately describe the event and the law surrounding it. This study takes that situation of uncertainty as its point of departure, and it unfolds through an analysis of the material conditions and linguistic–rhetoric and affective–psychic registers through which the Administrator of

RIFM fragrance ingredient safety assessment, 2-ethyl-1-hexanol, CAS registry number 104-76-7

The use of this material under current conditions is supported by existing information. This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization, as well as environmental safety. Data show that this material is not genotoxic. Data from the suitable read across analog 2-butyloct

Interaction gestures for a wearable device defined by visually impaired children

This paper reports results from two workshops organized with children with visual impairments ranging from blindness to low vision. The aim of the workshops was to suggest gestures for the interaction with a small wearable audio-bracelet. Results show a preference for mechanical buttons and touch-based gestures on the device (mainly tapping and sliding), while only one tentative suggestion is made

Extracellular Matrix Remodelling In COPD

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease that involves major remodelling of cells and tissue in the lung. There has been much focus on the inflammatory response, while less attention has been paid to structural changes and alterations of the extracellular matrix (ECM). In this review we revisit some of the latest findings on what is currently known about ECM a

Characterizing the Structure Tensor Using Gamma Distributions

The structure tensor is a powerful tool describing the local intensity structure of an image or image sequence. In this paper we give a model for the noise distribution of the components of the tensor. In order to do so we have also investigated some properties of the gamma distribution. We show that, given an input image corrupted with Gaussian noise, the noise in the structure tensor can be modeThe structure tensor is a powerful tool describing the local intensity structure of an image or image sequence. In this paper we give a model for the noise distribution of the components of the tensor. In order to do so we have also investigated some properties of the gamma distribution. We show that, given an input image corrupted with Gaussian noise, the noise in the structure tensor can be mode