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The Health and Structural Consequences of Acute Knee Injuries Involving Rupture of the Anterior Cruciate Ligament

Although there is an abundance of literature regarding the development of knee osteoarthritis after rupture of the anterior cruciate ligament (ACL), the mechanism underlying this link is not clear. Recent studies have reported that several factors may be predictive of the development of osteoarthritis, including damage to the menisci and articular cartilage during the initial trauma, altered knee

Ultra-high-speed pumping of an optical parametric oscillator (OPO) for high-speed laser-induced fluorescence measurements

The feasibility of pumping an optical parametric oscillator (OPO) with an ultra-high repetition rate multi:YAG laser system, producing a burst of up to eight high-energy pulses, has been investigated. For this investigation an OPO with a bandwidth around 5 cm(-1), together with a frequency doubling crystal, was selected. In some laser-induced fluorescence measurements the large linewidth from the

Proton-hole excitation in the closed shell nucleus Au-205

The neutron-rich N = 126 nucleus Au-205 has been populated following the relativistic energy projectile fragmentation of E/A = 1 GeV Pb-208, and studied via charged-particle decay spectroscopy. An internal decay with a transition energy of 907(5) keV and a half-life of T-1/2 = 6(2) s has been identified through the observation of the corresponding K and L internal conversion electron lines. The 90

Population Changes in Swedish Municipalities. What are the Reported Economic Impacts on Fee Financed Local Technical Services?

Swedish local governments are responsible for providing public services to their residents. Population changes require varying considerations and responses. Population growth demands the extension of the local government service capacity, for example to provide technical services. Even a declining population is demanding because of the difficulties adjusting the size of the service capacity in an

Modeling the dissolved organic carbon output from a boreal mire using the convection-dispersion equation: Importance of representing sorption

In this paper we present a model of the dissolved organic carbon (DOC) concentrations and fluxes in mire water based on the convection-dispersion equation. The dynamics of sorbed, potentially soluble organic carbon (SPSOC) in the peat matrix are simulated in parallel with DOC. First, the model is applied solely to stagnant water conditions in order to interpret the results of laboratory peat incub

Combining limnology and palaeolimnology to investigate recent regime shifts in a shallow, eutrophic lake

In this study, we demonstrate that an integrated approach, combining palaeolimnological records and limnological monitoring data, can increase our understanding of changing ecological patterns and processes in shallow lakes. We focused on recent regime shifts in shallow Lake Krankesjon, southern Sweden, including the collapse of the clear-water state in 1975 and its subsequent recovery in the late

Low Resolution Solution Structure of HAMLET and the Importance of Its Alpha-Domains in Tumoricidal Activity.

HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is the first member in a new family of protein-lipid complexes with broad tumoricidal activity. Elucidating the molecular structure and the domains crucial for HAMLET formation is fundamental for understanding its tumoricidal function. Here we present the low-resolution solution structure of the complex of oleic acid bound HAMLET, derived

The extent of relaxation of weld residual stresses on cutting out cross-weld test-pieces

Weld residual stress (RS) measurements are often undertaken on test-pieces which have been Cut Out from large components, yet it remains unclear to what extent the RSs in test-pieces are representative of those present in the original component. Similarly weld mechanical performance tests are frequently undertaken on cross-weld test-pieces without a proper understanding of the level or influence o

The Songbird Neurogenomics (SoNG) Initiative: Community-based tools and strategies for study of brain gene function and evolution

Background: Songbirds hold great promise for biomedical, environmental and evolutionary research. A complete draft sequence of the zebra finch genome is imminent, yet a need remains for application of genomic resources within a research community traditionally focused on ethology and neurobiological methods. In response, we developed a core set of genomic tools and a novel collaborative strategy t

The Ab Initio No-core Shell Model

This contribution reviews a number of applications of the ab initio no-core shell model (NCSM) within nuclear physics and beyond. We will highlight a nuclear-structure study of the A = 12 isobar using a chiral NN + 3NF interaction. In the spirit of this workshop we will also mention the new development of the NCSM formalism to describe open channels and to approach the problem of nuclear reactions

Partitioning and Mapping Dynamic Dataflow Programs

Partitioning and mapping are important design decisions in exploiting the parallelism of programs that are to be run on systems with multiple processing elements. In this paper we introduce a fast, incremental approach for mapping dynamic dataflow programs to multiprocessor systems. We use causation traces and architecture descriptions as input for the mapping process that devises several heuristi

On the Value of Double Vision

This article is, first, an analysis of arguments that have been leveled against systematic empirical research in psychoanalysis. The arguments are basically two: It cannot uncover unobservable processes, and it cannot account for the uniqueness of the psychoanalytic dyad. Therefore, systematic empirical research is said to be incompatible with basic tenets of psychoanalysis. Both arguments are ref

How to obtain statistically converged MM/GBSA results.

The molecular mechanics/generalized Born surface area (MM/GBSA) method has been investigated with the aim of achieving a statistical precision of 1 kJ/mol for the results. We studied the binding of seven biotin analogues to avidin, taking advantage of the fact that the protein is a tetramer with four independent binding sites, which should give the same estimated binding affinities. We show that i