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Solar Light Degradation of Trimethyl Phosphate and Triethyl Phosphate on Dry and Water-Precovered Hematite and Goethite Nanoparticles

We report on the solar-light-mediated degradation of trimethyl phosphate (TMP) and triethyl phosphate (TEP) on hematite and goethite nanoparticles in synthetic air. Adsorption and photoreactions of TMP and TEP were studied by in situ diffuse reflectance Fourier transform infrared spectroscopy (DRIFTS) on dry and water-precovered nanoparticles in dark and under simulated solar light irradiation. Tw

Physical activity reduces the risk of incident type 2 diabetes in general and in abdominally lean and obese men and women: the EPIC-InterAct Study

We examined the independent and combined associations of physical activity and obesity with incident type 2 diabetes in men and women. The InterAct case-cohort study consists of 12,403 incident type 2 diabetes cases and a randomly selected subcohort of 16,154 individuals, drawn from a total cohort of 340,234 participants with 3.99 million person-years of follow-up. Physical activity was assessed b

Design concepts for the Cherenkov Telescope Array CTA: an advanced facility for ground-based high-energy gamma-ray astronomy

Ground-based gamma-ray astronomy has had a major breakthrough with the impressive results obtained using systems of imaging atmospheric Cherenkov telescopes. Ground-based gamma-ray astronomy has a huge potential in astrophysics, particle physics and cosmology. CTA is an international initiative to build the next generation instrument, with a factor of 5-10 improvement in sensitivity in the 100 GeV

Two intuitions about free will: Alternative possibilities and intentional endorsement

Free will is widely thought to require (i) the possibility of acting otherwise and (ii) the making of choices that are intentionally endorsed, not just indeterministically picked. According to (i), a necessary condition for free will is agential-level indeterminism: at some points in time, an agent’s prior history admits more than one possible continuation. According to (ii), however, this indeter

Mendacity and Kingship in Shakespeare's Henry V and Richard III

Shakespeare’s Henry V and Richard III both practise mendacity, but while Henry V celebrates Henry’s capacity for deceit, the king’s lies are condemned in Richard III. The plays show how similar patterns of behaviour in early modern England could be represented as either virtuous or evil by means of rhetoric, while the similar behaviour of the two kings suggests a broad awareness of the necessity o

Inherited variation in the PARP1 gene and survival from melanoma

We report the association of an inherited variant located upstream of the poly(adenosine diphosphate-ribose) polymerase 1 (PARP1) gene (rs2249844), with survival in 11 BioGenoMEL melanoma cohorts. The gene encodes a protein involved in a number of cellular processes including single-strand DNA repair. Survival analysis was conducted for each cohort using proportional hazards regression adjusting f

Early life low-level cadmium exposure is positively associated with increased oxidative stress

Environmental exposure to cadmium (Cd) is known to induce oxidative stress, a state of imbalance between the production of reactive oxygen species (ROS) and the ability to detoxify them, in adults. However, data are lacking on potential effects in early-life. We evaluated urinary concentrations of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), a recognized marker of oxidative DNA damage, in relati

PATIENT DOSIMETRY IN NUCLEAR MEDICINE.

In diagnostic nuclear medicine, the biokinetics of the radiopharmaceutical (actually of the radionuclide) is determined for a number of representative patients. At therapy, it is essential to determine the patient's individual biokinetics of the radiopharmaceutical in order to calculate the absorbed doses to critical normal organs/tissues and to the target volume(s) with high accuracy. For the dia

A Wnt5a signaling pathway in the pathogenesis of HIV-1 gp120-induced pain.

Pathological pain is one of the most common neurological complications in HIV-1/AIDS patients. However, the pathogenic process is unclear. Our recent studies show that Wnt5a is up-regulated in the spinal dorsal horn (SDH) of the HIV patients who develop pain and that HIV-1 gp120, a potential causal factor of the HIV-associated pain, rapidly up-regulates Wnt5a in the mouse SDH. Using a mouse model,

Impaired quality of life and sexual function in overweight and obese men: the European Male Ageing Study

Background: Few published data link overweight and obesity with measures of quality of life (QoL) including sexual health in men. Objective: To assess the association of overweight/obesity with impairment of physical and psychological QoL and sexual functions in men. Design and setting: Cross-sectional, multicentre survey of 3369 community-dwelling men aged 40-79 (mean +/- S.D., 60 +/- 11) years r

Coveted, detested and unattainable? Images of the US superpower role and self-images of Russia in Russian print media discourse

This article explores how the image of the USA has developed in two major Russian daily newspapers, Izvestiya and Komsomolskaya Pravda, in a time period comprised of a total 20 weeks’ of study in the years of 1984, 1994, 2004 and 2009. For Russia this time span was dramatic: it moved from seemingly stable superpower in the 1980s, over the chaos after the dissolution of the Soviet Union in the 1990

Visual modelling suggests a weak relationship between the evolution of ultraviolet vision and plumage coloration in birds.

Birds have sophisticated colour vision mediated by four cone types that cover a wide visual spectrum including ultraviolet (UV) wavelengths. Many birds have modest UV sensitivity provided by violet-sensitive (VS) cones with sensitivity maxima between 400 and 425 nm. However, some birds have evolved higher UV sensitivity and a larger visual spectrum given by UV-sensitive (UVS) cones maximally sensi

Unit cell parameters of wurtzite InP nanowires determined by x-ray diffraction

High resolution x-ray diffraction is used to study the structural properties of the wurtzite polytype of InP nanowires. Wurtzite InP nanowires are grown by metal-organic vapor phase epitaxy using S-doping. From the evaluation of the Bragg peak position we determine the lattice parameters of the wurtzite InP nanowires. The unit cell dimensions are found to differ from the ones expected from geometr

Galvanic corrosion properties of steel in water saturated concrete

Aluminum-based sacrificial anodes were installed to reinforced concrete to stop ongoing corrosion in cooling water tunnels in a Swedish nuclear power plant. The steel rebars were also unintentionally connected to stainless steel water pumps. Therefore, the consumption rate of the sacrificial anodes was higher than predicted. An experimental and a field study were performed to assess if the steel r

Hypo- and hypercapnia predict mortality in oxygen-dependent chronic obstructive pulmonary disease: a population-based prospective study

Background: The prognostic role of the arterial blood gas tension of carbon dioxide (PaCO2) in severe Chronic Obstructive Pulmonary Disease (COPD) remains unknown. The aim of this study was to estimate the association between PaCO2 and mortality in oxygen-dependent COPD. Methods: National prospective study of patients starting long-term oxygen therapy (LTOT) for COPD in Sweden between October 1, 2

Temperature adaptation of bacterial communities in experimentally warmed forest soils

A detailed understanding of the influence of temperature on soil microbial activity is critical to predict future atmospheric CO2 concentrations and feedbacks to anthropogenic warming. We investigated soils exposed to 3-4 years of continuous 5 degrees C-warming in a field experiment in a temperate forest. We found that an index for the temperature adaptation of the microbial community, T-min for b

A pooled analysis of the effect of endovascular cooling on infarct size in patients with ST-elevation myocardial infarction.

Aims: Prior evaluations of endovascular cooling during primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) have suggested variability in treatment effect related to core temperature at the time of reperfusion, to infarct location and time from symptom onset to reperfusion. Recent results from a randomised feasibility study suggest rapid induction of hypothermia i