BACKGROUND: Treatment with intravenous immunoglobulin (IVIG) in children with Paediatric Acute-onset Neuropsychiatric Syndrome (PANS) has for many years been used on clinical indications, but the research evidence for its efficacy is insufficient.METHODS: Open-label prospective in-depth trial including ten children (median age 10.3 years) with PANS, who received IVIG treatment 2 g/kg monthly for t

Neuropsychiatric and neurodevelopmental disorders are often associated with coordination problems. Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) constitutes a specific example of acute and complex symptomatology that includes difficulties with motor control. The present proof-of-concept study aimed at testing a new, bespoke tablet-based motor coordination test named SpaceSwipe, providing

This thesis aimed to develop and apply methods for evaluating social and motor coordination, domains that often are challenged in individuals with neurodevelopmental/neuropsychiatric disorders (NDDs), also referred within Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations (ESSENCE). In Study I, we created a new tablet-based motor test that could accurately probe motor c

This paper concerns control of a class of systems where multiple dynamically stable agents share a nonlinear and bounded control-interconnection. The agents are subject to a disturbance which is too large to reject with the available control action, making it impossible to stabilize all agents in their desired states. In this nonlinear setting, we consider two different anti-windup equipped propor

Tropical oceans are the main global water vapor and latent heat sources, but their responses to radiative forcing remain unclear. Here, we investigate oceanic moisture dynamics of the western tropical Pacific (WTP) over the past 210,000 years through an approach of planktonic foraminiferal triple oxygen isotope (Δ′17O). The Δ′17O record is dominated by the precession cycles (~23,000 years), with l

In many liquid food processing applications using high-pressure homogenizers (HPHs), particles impact with the solid surfaces of the homogenization device. This may lead to costly wear. For some applications, impact is also postulated to control the desired cell disruption. This contribution uses computational fluid dynamics to study impact of particles on solid surfaces in HPHs, as a step towards

High-pressure homogenizers are used extensively in food and beverage processing. For design and operation optimization, it is vital to understand where breakup takes place. Using an experimental high-speed camera setup on a scaled model, this contribution shows that breakup events can occur inside of the gap of a homogenizer valve. This contrasts with many previous studies which only observe break

Introduction: Airway management is a critical component of out-of-hospital cardiac arrest (OHCA) resuscitation. The primary aim of this study was to describe pre-hospital airway management in adult patients post-OHCA. Secondary aims were to investigate whether tracheal intubation (TI) versus use of supraglottic airway device (SGA) was associated with patients’ outcomes, including ventilator-free d

Comic art has been described as having an ability to challenge taken for granted assumptions, illuminate cultural norms, and contest and give space for alternative imaginaries. Approaching comics as both art and activism, this chapter takes hold of the capacity in comic art to make visible and shape action in relation to social conventions and cultural norms. It does so by reading comics through a

We develop a multiscale coarse-grain model of the NIST Monoclonal Antibody Reference Material 8671 (NISTmAb) to enable systematic computational investigations of high-concentration physical instabilities such as phase separation, clustering, and aggregation. Our multiscale coarse-graining strategy captures atomic-resolution interactions with a computational approach that is orders of magnitude mor

Kort biografisk artikel om den tidiga kvinnliga läkaren och sexualupplyserskan Sofia Holmgren. Utgör del av den virtuella utställningen "150 år med kvinnor vid akademin".

Kort biografisk artikel om den första kvinnan att disputera i medicin vid Lunds universitet. Utgör del av den virtuella utställningen "150 år med kvinnor vid akademin".

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Kort biografisk artikel om tidig, politiskt radikal och aktiv studentska vid Lunds universitet. Utgör del av den virtuella utställningen "150 år med kvinnor vid akademin".

For decades, the environmental sciences have engaged in measuring and modelling natural systems to increase our understanding and prediction of climate change. This thesis advances these efforts by analyzing and applying in-situ instruments, remote sensing, and modelling approaches. The main focus lies in utilizing a state-of-the-art global Earth System Model (ESM) EC-Earth3, which is used to simu

Three species new to science in the genus Xanthoria (Teloschistaceae), X. pedersenii, X. pylyporlykii and X. wennergrenii, from the southwestern Baltic Sea region, are presented and compared with related species.

This reflection explores the anxiety and physical sensations felt by some scholars when navigating interdisciplinary research. The author describes personally experienced physical and emotional challenges faced during collaborative research, emphasizing the lack of common language and knowledge, and arguing for greater acknowledgment of these embodied experiences. The aim is to foster more honest

Colorful flower patterns are key signals to attract pollinators. To produce such motifs, plants specify boundaries dividing petals into subdomains where cells develop distinctive pigmentations, shapes, and textures. While some transcription factors and biosynthetic pathways behind these characteristics are well studied, the upstream processes restricting their activities to specific petal regions