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ROTEM monitoring of activated and non-activated prothrombin complex concentrate correction of dilutional coagulopathy.

Objectives Prothrombin complex concentrates have been used to correct dilutional coagulopathy, but many preparations contain anticoagulants, such as heparin, to counteract their prothrombotic effects. These anticoagulants can interfere with haemostatic assays. The aim of this study was to monitor two different prothrombin complex concentrates for the treatment of albumin dilution in vitro, using r

Effects of agitation on particle-size distribution and enzymatic hydrolysis of pretreated spruce and giant reed.

Mixing is an energy demanding process which has been previously shown to affect enzymatic hydrolysis. Concentrated biomass slurries are associated with high and non-Newtonian viscosities and mixing in these systems is a complex task. Poor mixing can lead to mass and/or heat transfer problems as well as inhomogeneous enzyme distribution, both of which can cause possible yield reduction. Furthermore

Variety in Fruit and Vegetable Consumption and the Risk of Lung Cancer in the European Prospective Investigation into Cancer and Nutrition

Background: We investigated whether a varied consumption of vegetables and fruits is associated with lower lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study. Methods: After a mean follow-up of 8.7 years, 1,613 of 452,187 participants with complete information were diagnosed with lung cancer. Diet diversity scores (DDS) were used to quantify the variety in f

Principal Component Abundance Analysis of Microlensed Bulge Dwarf and Subgiant Stars

Elemental abundance patterns can provide vital clues to the formation and enrichment history of a stellar population. Here we present an investigation of the Galactic bulge, where we apply principal component abundance analysis (PCAA) - a principal component decomposition of relative abundances [X/Fe] to a sample of 35 microlensed bulge dwarf and subgiant stars, characterizing their distribution i

tmRNA-SmpB complex mimics native aminoacyl-tRNAs in the A site of stalled ribosomes

Bacterial ribosomes stalled on faulty, often truncated, mRNAs lacking stop codons are rescued by trans-translation. It relies on an RNA molecule (tmRNA) capable of replacing the faulty mRNA with its own open reading frame (ORF). Translation of tmRNA ORF results in the tagging of faulty protein for degradation and its release from the ribosome. We used single-particle cryo-electron microscopy to vi

Adolescents born extremely preterm: behavioral outcomes and quality of life

Hallin, A.-L., Stjernqvist, K. (2010). Adolescents born extremely preterm: behavioral outcomes and quality of life. Scandinavian Journal of Psychology. Fifty-two extremely premature born and 54 full-term controls were assessed regarding behavioral outcomes, risk-taking and self-perceived quality of life. Behavioral outcomes were assessed with the Achenbach Youth Self Report; risk-taking was estima

Rektorer bör och rektorer gör

The purpose of the thesis is to study whether any special professional norms exist with regard to principals’ leadership of the democratic mission which is presented to the schools. The aim is to identify norms in order to be able to later analyse and understand them. Norms exist in groups of various types, and by using the term “norm” I am addressing the actions of principals, rather than their i

Impact of hypoxia, simulated ischemia and reperfusion in HL-1 cells on the expression of FKBP12/FKBP12.6 and intracellular calcium dynamics

Aims: To establish a cardiac cell culture model for simulated ischemia and reperfusion and in this model investigate the impact of simulated ischemia and reperfusion on expression of the calcium handling proteins FKBP12 and FKBP12.6, and intracellular calcium dynamics. Methods: HL-1 cell cultures were exposed to normoxia (as control), hypoxia, simulated ischemia (HEDA) or HEDA + reactive oxygen sp

Consumer behavior and perspectives concerning spent household battery collection and recycling in China: a case study

Currently, the majority of spent batteries are not recycled but become part of the household waste in many countries, especially in China which is the largest producer and consumer of batteries. This is due to many reasons, including the lack of governmental policies to encourage and facilitate battery return and recycling. In that context this research was designed to investigate the attitudes an

Transverse-momentum dependence of the J/psi nuclear modification in d+Au collisions at root s(NN)=200 GeV

We present measured J/psi production rates in d + Au collisions at root s(NN) = 200 GeV over broad ranges of transverse momentum (p(T) = 0-14 GeV/c) and rapidity (-2.2 < y < 2.2). We construct the nuclear-modification factor R-dAu for these kinematics and as a function of collision centrality (related to impact parameter for the d + Au collision). We find that the modification is largest for colli

Leverage effect for volatility with generalized Laplace error

We propose a new model that accounts for the asymmetric response of volatility to positive (`good news') and negative (`bad news') shocks in economic time series – the so-called leverage effect. In the past, asymmetric powers of errors in the conditionally heteroskedastic models have been used to capture this effect. Our model is using the gamma difference representation of the generalized Laplace

Challenges and opportunities for future production of food, feed and biofuel - A land use perspective

The world is facing of a number of great challenges as the population is growing and living habits are getting more resource demanding. At the same time as food security has to be assured, growth in biofuel and meat production pose a risk for increasing land use conflicts and negative environmental consequences. In this report production of food, feed and biofuels are discussed from a land use pe

The supply and demand of net primary production in the Sahel

Net primary production (NPP) is the principal source of energy for ecosystems and, by extension, human populations that depend on them. The relationship between the supply and demand of NPP is important for the assessment of socio-ecological vulnerability. We present an analysis of the supply and demand of NPP in the Sahel using NPP estimates from the MODIS sensor and agri-environmental data from

CSF amyloid beta 38 as a novel diagnostic marker for dementia with Lewy bodies

Background The clinical distinction between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) is sometimes difficult, particularly in mild cases. Although CSF markers such as amyloid beta 42 (A beta 42) and P-tau can distinguish between AD and normal controls, their ability to distinguish between AD and DLB is not adequate. Objective This study aims to investigate whether CSF markers, i

Non-traditional stochastic models for ocean waves

We present two flexible stochastic models for 2D and 3D ocean waves with potential to reproduce severe and non-homogeneous sea conditions. The first family consists of generalized Lagrange models for the movements of individual water particles. These models can generate crest-trough and front-back statistically asymmetric waves, with the same degree of asymmetry as measured ocean waves. They are s