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Compendium of Front-End Electronics

Our world is changing fast. On one hand, technological developments provide us with new and powerful electronics devices on almost a weekly basis. On the other hand, the end-user of these electronics is now rarely required to actually configure the devices, as everything is automated. This "de-empowerment" of the end-user may be detrimental to the scientific community. This is because the unique c

Sentinel Lymph Node Biopsy in Thyroid Cancer

Background: Prophylactic central neck dissection in patients with papillary thyroid carcinoma is controversial. Sentinel node biopsy might be an adjunct to optimize surgical treatment for these patients. Earlier studies reported inconsistent detection rates and diagnostic value of this technique, and the role of sentinel lymph node biopsy in thyroid cancer needs to be established. Patients and met

The Dislocated Vernacular in Translated Swedish Working-Class Fiction

When a literary text is translated from a dominated to a dominating language, Yvonne Lindqvist (2018) observes, it generally undergoes a cosmopolitanizing process. Consecrated by the dominating literary culture, the text is lifted up to a transnational level and deemed significant for an international readership. Lindqvist’s observation is confirmed by the English translations of Swedish working-c

The intrinsically disordered RNR inhibitor Sml1 is a dynamic dimer

Sml1 is a small ribonucleotide reductase (RNR) regulatory protein in Saccharomyces cerevisiae that binds to and inhibits RNR activation. NMR studies of 15N-labeled Sml1 (104 residues), as well as of a truncated variant (residues 50−104), have allowed characterization of their molecular properties. Sml1 belongs to the class of intrinsically disordered proteins with a high degree of dynamics and ver

Neonatal clinical blood sampling led to major blood loss and was associated with bronchopulmonary dysplasia

Aim: Studies indicate that reduced foetal haemoglobin levels are related to increased neonatal morbidity rates. This study investigated the relationships between sampling-related blood loss and adult blood transfusions administered during postnatal days 1-14 and the development of severe neonatal morbidities in extremely preterm infants born before 28 weeks of gestation. Methods: The medical files

Attending Heart School and long-term outcome after myocardial infarction : A decennial SWEDEHEART registry study

Background: The Heart School is a standard component of cardiac rehabilitation after myocardial infarction in Sweden. The group-based educational intervention aims to improve modifiable risks, in turn reducing subsequent morbidity and mortality. However, an evaluation with respect to mortality is lacking. Aims: Using linked population registries, we estimated the association of attending Heart Sch

CCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway

Epithelial ovarian cancer (EOC) is considered to secrete various factors in order to promote peritoneal dissemination through cell-to-cell interaction between cancer and mesothelial cells. We previously revealed that TGF-β secreted from EOC induces normal human peritoneal mesothelial cells (HPMCs) to differentiate into cancer-associated mesothelial cells (CAMCs). However, the relationship between

The Revival of Agriculture and Inclusive Growth during the Commodity Boom in Latin America?

Latin America has constituted a recent example of inclusive growth by reducing poverty and income inequality simultaneously during the latest commodity boom. Against the backdrop of non-inclusive and non-transformative nature of commodity booms, we ask whether growth of agriculture was able to speed up structural transformation, and, relatedly, if agricultural growth was inclusive. We examine 16 c

Is timing of reproduction according to temperature sums an optimal strategy?

Temperature sums are widely used to predict the seasonal timing of yearly recurring biological events, such as flowering, budburst, and hatching. We use a classic energy allocation model for annual plants to compare a strategy for reproductive timing that follows a temperature sum rule (TSR) with a strategy that follows an optimal control rule (OCR) maximizing reproductive output. We show that the

Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons

In Parkinson's disease, the degeneration of dopaminergic neurons in substantia nigra leads to a decrease in the physiological levels of dopamine in striatum. The existing dopaminergic therapies effectively alleviate the symptoms, albeit they do not revert the disease progression and result in significant adverse effects. Transplanting dopaminergic neurons derived from stem cells could restore dopa

Analysis of early-flowering genes at barley chromosome 2H expands the repertoire of mutant alleles at the Mat-c locus

Key message: Analyses of barley mat-c loss of function mutants reveal deletions, splice-site mutations and nonsynonymous substitutions in a key gene regulating early flowering. Abstract: Optimal timing of flowering is critical for reproductive success and crop yield improvement. Several major quantitative trait loci for flowering time variation have been identified in barley. In the present study,

Utgör livsmedelspriser en barriär mot en hälsosam kost?

Förekomsten av kostrelaterade sjukdomar ökar, framför allt i grupper som lever under ekonomisk knapphet. Detta förklaras ofta med det höga priset på eller den höga prisökningstakten för hälsosamma livsmedel. De samhällsekonomiska implikationerna av en sådan förklaring är omfattande eftersom de motiverar mer omfattande omfördelning eller prismanipulation som lösning på hälsoproblemen. Detta bidrag

Stockholmare, flytta dit bostäderna finns

På samma sätt som det är naturligt för ungdomar från bruksorter att flytta till Stockholm bör Stockholmsungdomar ställa in sig på att flytta ut från stan, skriver Ingemar Bengtsson, universitetslektor i fastighetsvetenskap vid Lunds universitet.

Droplet Breakup in High-Pressure Homogenizers

In this chapter, a detailed review of the current understanding of thephysical processes of droplet breakup in a high-pressure homogenizer (HPH) is presented,covering breakup mechanisms by laminar shear in the gap inlet and its boundarylayers, by local turbulence in the gap exit jet, and by cavitation. Experimentalevidence of the effects of homogenization pressure, Thoma number, dispersed andcontiIn this chapter, a detailed review of the current understanding of the physical processes of droplet breakup in a high-pressure homogenizer (HPH) is presented, covering breakup mechanisms by laminar shear in the gap inlet and its boundary layers, by local turbulence in the gap exit jet, and by cavitation. Experimental evidence of the effects of homogenization pressure, Thoma number, dispersed and

Vad ska vi med föreläsningar till?

Föreläsningen är en märklig undervisningsform. Samtidigt som den är den vanligast förekommandemetoden, är den också den mest föraktade. Det finns gott om högskolepedagogisklitteratur som förklarar varför föreläsningen är olämplig för att stimulera lärande. Ändåfortsätter vi föreläsa. Det kan tyckas motsägelsefullt.Denna reflektion vänder på frågan och letar efter föreläsningens fördelar. Utifrån t

Quantitative T-wave morphology assessment from surface ECG is linked with cardiac events risk in genotype-positive KCNH2 mutation carriers with normal QTc values

Introduction: Long QT syndrome (LQTS) mutation carriers have elevated the risk of cardiac events even in the absence of QTc prolongation; however, mutation penetrance in patients with normal QTc may be reflected in abnormal T-wave shape, particularly in KCNH2 mutation carriers. We aimed to assess whether the magnitude of a three-dimensional T-wave vector (TwVM) will identify KCNH2-mutation carrier

Construct validity of a revised version of the Occupational Balance Questionnaire

Background: Occupational balance is fundamental to occupational therapy and occupational science. Therefore, the Occupational Balance Questionnaire (OBQ) was developed and has previously been found psychometrically valid according to classical test theory. Aim: To investigate the internal construct validity of the OBQ using Rasch measurement theory. Material and methods: Data from two general popu

Parametric study and optimization on heat transfer and flow characteristics in a rectangular channel with longitudinal vortex generators

In this study, effects of various geometrical parameters of a new winglet longitudinal vortex generator (LVG) on heat transfer and flow characteristics in a rectangular channel were investigated by a numerical method, and the influence of various parameters was analyzed. A comparative study of effects of elliptical pole parameters, the thickness, the length, the height, the attack angle, the trans

All-polyethylene versus metal-backed posterior stabilized total knee arthroplasty : similar 2-year results of a randomized radiostereometric analysis study

Background and purpose — The all-polyethylene tibial (APT) component, introduced in the early 1970s, was surpassed by metal-backed tibial (MBT) trays as the first choice for total knee arthroplasty (TKA). With improved polyethylene, the modern APT components can reduce costs, and have shown equivalent results in survivorship and early migration of the cruciate-retaining and cruciate-stabilizing de