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The EAT-Lancet Diet Index, Plasma Proteins, and Risk of Heart Failure in a Population-Based Cohort

BACKGROUND: The landmark EAT-Lancet Commission proposed that a planetary health diet is comprised mainly of plant-based foods. However, studies examining whether this diet is associated with heart failure (HF) are currently lacking. In addition, the potential proteomics mechanism on the association between diet and HF warrants further elucidation.OBJECTIVES: This study aims to both examine the ass

The effects of gaze-display feedback on medical students’ self-monitoring and learning in radiology

Self-monitoring is essential for effectively regulating learning, but difficult in visual diagnostic tasks such as radiograph interpretation. Eye-tracking technology can visualize viewing behavior in gaze displays, thereby providing information about visual search and decision-making. We hypothesized that individually adaptive gaze-display feedback improves posttest performance and self-monitoring

Tumor Budding is a Weak Predictor of Oncological Outcomes in Colorectal Cancer: A Cohort Study

Background: Tumor budding (Bd) is a suggested risk factor for recurrence and decreased survival in colorectal cancer. Histopathological detection of Bd indicates increased invasive and migratory potential of the tumor cells.Objectives: This study aimed to explore the impact of Bd on oncological outcomes.Design: Retrospective cohort study.Patient and Methods: Patients treated with abdominal curativ

Prostate Cancer Screening With PSA, Kallikrein Panel, and MRI : The ProScreen Randomized Trial

IMPORTANCE: Prostate-specific antigen (PSA) screening has potential to reduce prostate cancer mortality but frequently detects prostate cancer that is not clinically important.OBJECTIVE: To describe rates of low-grade (grade group 1) and high-grade (grade groups 2-5) prostate cancer identified among men invited to participate in a prostate cancer screening protocol consisting of a PSA test, a 4-ka

Clinical characteristics of adolescents and emerging adults presenting for integrated posttraumatic stress and substance use treatment

Adolescence and emerging adulthood are key developmental stages with high risk for trauma exposure and the development of mental and substance use disorders (SUDs). The aim of this study was to compare the clinical profiles of adolescents (aged 12-17 years) and emerging adults (aged 18-25 years) presenting for treatment of posttraumatic stress disorder (PTSD) and SUD. Design/methodology/approach:

The Specter of Potential Foreigners : Revisiting the Postcolonial Citizenship Regimes of Myanmar and India

Revisiting the citizenship regimes of Myanmar and India through a comparative lens, this article argues that a specter of the “potential foreigner” is decisive in the adjudication of citizenship in both countries. Citizenship is conceptualized not only on the basis of who is a citizen, but a perennial suspicion towards those who may not be. We frame this argument in the context of increasingly res

Photophysical image analysis : Unsupervised probabilistic thresholding for images from electron-multiplying charge-coupled devices

We introduce the concept photophysical image analysis (PIA) and an associated pipeline for unsupervised probabilistic image thresholding for images recorded by electron-multiplying charge-coupled device (EMCCD) cameras. We base our approach on a closed-form analytic expression for the characteristic function (Fourier-transform of the probability mass function) for the image counts recorded in an E

The Russian threat and the consolidation of the West: How populism and EU-skepticism shape party support for Ukraine

Support for Ukraine against Russian aggression has been strong across Europe, but it is far from uniform. An expert survey of the positions taken by political parties in 29 countries conducted mid-2023 reveals that 97 of 269 parties reject one or more of the following: providing weapons, hosting refugees, supporting Ukraine's path to European Union membership, or accepting higher energy costs. Whe

Bacterial community characterization by deep learning aided image analysis in soil chips

Soil microbes play an important role in governing global processes such as carbon cycling, but it is challenging to study them embedded in their natural environment and at the single cell level due to the opaque nature of the soil. Nonetheless, progress has been achieved in recent years towards visualizing microbial activities and organo-mineral interaction at the pore scale, especially thanks to

On the computational complexity of ethics : moral tractability for minds and machines

Why should moral philosophers, moral psychologists, and machine ethicists care about computational complexity? Debates on whether artificial intelligence (AI) can or should be used to solve problems in ethical domains have mainly been driven by what AI can or cannot do in terms of human capacities. In this paper, we tackle the problem from the other end by exploring what kind of moral machines areWhy should moral philosophers, moral psychologists, and machine ethicists care about computational complexity? Debates on whether artificial intelligence (AI) can or should be used to solve problems in ethical domains have mainly been driven by what AI can or cannot do in terms of human capacities. In this paper, we tackle the problem from the other end by exploring what kind of moral machines are

Production of η and η′ mesons in pp and pPb collisions

The production of η and η′ mesons is studied in proton-proton and proton-lead collisions collected with the LHCb detector. Proton-proton collisions are studied at center-of-mass energies of 5.02 and 13TeV and proton-lead collisions are studied at a center-of-mass energy per nucleon of 8.16TeV. The studies are performed in center-of-mass (c.m.) rapidity regions 2.5

A Dynamic Capabilities Approach to Sustainable Business Model Innovation : A Case Study of the Swedish Architecture Industry

Firms today are facing changing conditions which they must respond to in order to maintain a sustained competitive advantage. To address this change, practitioners such as managers and executives of large firms look towards the concepts of Business Models and Business Model Innovation, as tools to devise and execute strategies to manage that change. This study will present an in-depth comparative

Curvature-bias corrections using a pseudomass method

Momentum measurements for very high momentum charged particles, such as muons from electroweak vector boson decays, are particularly susceptible to charge-dependent curvature biases that arise from misalignments of tracking detectors. Low momentum charged particles used in alignment procedures have limited sensitivity to coherent displacements of such detectors, and therefore are unable to fully c

Elevated expression of complement factor I in lung cancer cells associates with shorter survival–Potentially via non-canonical mechanism

While numerous membrane-bound complement inhibitors protect the body's cells from innate immunity's autoaggression, soluble inhibitors like complement factor I (FI) are rarely produced outside the liver. Previously, we reported the expression of FI in non-small cell lung cancer (NSCLC) cell lines. Now, we assessed the content of FI in cancer biopsies from lung cancer patients and associated the re

Stories With Blurred Contours Family Displays of Foster Families and Young Children in Out-of-Home Care

The aim of the study was to investigate foster parents' displays and narratives about family life as foster parents of toddlers and preschool children and how these influence the welfare and sense of family belonging for younger children in foster care. Based on qualitative interviews with 16 foster parents in 10 foster families of looked-after children aged 1–6, narratives about the children, the

Retrospective genetic testing (Traceback) in women with early-onset breast cancer after revised national guidelines : a clinical implementation study

Purpose: This study focused on identifying a hereditary predisposition in women previously diagnosed with early-onset breast cancer through a retrospective outreach activity (Traceback). The objectives were to evaluate the possible clinical implementation of a simplified Traceback strategy and to identify carriers of pathogenic variants among previously untested women. Methods: Three hundred and f