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Closed-form H-infinity optimal control for a class of infinite-dimensional systems

H-infinity optimal control and estimation are addressed for a class of systems governed by partial differential equations with bounded input and output operators. Diffusion equations are an important example in this class. Explicit formulas for the optimal state feedback controller as well as the optimal state estimator are given. Unlike traditional methods for H-infinity synthesis, no iteration i

Optimisation based material parameter identification using full field displacement and temperature measurements

A material parameter identification is presented for a fully thermo-mechanically coupled material model based on full field displacement and temperature measurements. The basic theory of the inverse problem is recapitulated, focusing on the choice of the objective function, proposing a new formulation, and explaining in detail the necessary numerical treatment of experimental data during the pre-p

Accurate solution-adaptive finite difference schemes for coarse and fine grids

We introduce solution dependent finite difference stencils whose coefficients adapt to the current numerical solution by minimizing the truncation error in the least squares sense. The resulting scheme has the resolution capacity of dispersion relation preserving difference stencils in under-resolved domains, together with the high order convergence rate of conventional central difference methods

Nonlinear homogenization for topology optimization

Non-linear homogenization of hyperelastic materials is reviewed and adapted to topology optimization. The homogenization is based on the method of multiscale virtual power in which the unit cell is subjected to either macroscopic deformation gradients or equivalently to Bloch type displacement boundary conditions. A detailed discussion regarding domain symmetry of the unit cell and its effect on u

No-touch saphenous vein grafts in coronary artery surgery (SWEDEGRAFT) : Rationale and design of a multicenter, prospective, registry-based randomized clinical trial

The SWEDEGRAFT study (ClinicalTrials.gov Identifier: NCT03501303) tests the hypothesis that saphenous vein grafts (SVGs) harvested with the “no-touch” technique improves patency of coronary artery bypass grafts compared with the conventional open skeletonized technique. This article describes the rationale and design of the randomized trial and baseline characteristics of the population enrolled d

Towards eye tracking as a support tool for pilot training and assessment

A key challenge in pilot training and performance assessment is the lack of insight into pilot visual behavior. Without this, it is difficult for an instructor to assess, e.g., whether pilots fail because they did not monitor the instruments or because they did not act on them, and whether pilots comply with monitoring aspects of the Standard Operating Procedures. Eye tracking provides the opportu

A proposed amendment to the current guidelines for mild traumatic brain injury : reducing computerized tomographies while maintaining safety

Purpose: Head trauma is a common complaint in emergency departments. Identifying patients with serious injuries can be difficult and generates many computerized tomographies. Reducing the number of computerized tomographies decreases both cost and radiation exposure. The aim of this study was to evaluate whether the current Scandinavian Neurotrauma Committee guidelines could be revised in such a w

Antibiotic susceptibility patterns and clones of Pseudomonas aeruginosa in Swedish ICUs

Pseudomonas aeruginosa is 1 of the bacteria most adaptive to anti-bacterial treatment. Previous studies have shown nosocomial spread and transmission of clonal strains of P. aeruginosa in European hospitals. In this study we investigated antibiotic susceptibility and clonality in 101 P. aeruginosa isolates from 88 patients admitted to 8 Swedish ICUs during 2002. We also compared phenotypes and gen

Antibiotic prescription practices, consumption and bacterial resistance in a cross section of Swedish intensive care units

Background: The purpose of this work was to study usage of antibiotics, its possible determinants, and patterns of bacterial resistance in Swedish intensive care units (ICUs). Methods: Prospectively collected data on species and antibiotic resistance of clinical isolates and antibiotic consumption specific to each ICU in 1999 were analyzed together with answers to a questionnaire. Antibiotic usage