Objective: Increased soluble levels of complement effectors have been demonstrated in active anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), but the timing of complement activation in the autoimmune inflammation remains elusive. This study investigated whether the complement system is activated before onset of symptoms in AAV. Method: The Swedish National Patient Register

MethodsA retrospective review of a prospectively maintained database of all VS patients treated with 12Gy prescription dose between September 2005 and June 2011 at our institution using the Leksell Model 4C Gamma Knife Unit was conducted. Patients who had a minimum of 12-months clinical and radiological assessment before and after radiosurgery were included in this study. Tumor growth rates were c

Surface affinity, orientation and ion pairing are investigated in mixed and single solute systems of aqueous sodium hexanoate and hexylammonium chloride. The surface sensitive X-ray photoelectron spectroscopy technique has been used to acquire the experimental results, while the computational data have been calculated using molecular dynamics simulations. By comparing the single solute solutions w

The combustibility of timber is one of the main reasons that many building regulations strictly limit the use of timber as a building material. Fire safety is an important contribution to feeling safe, and an important criterion for the choice of building materials. Historically, the combustibility aspect of wood has been a disadvantage for using timber as a construction material. The main precond

Multi-nucleotide variants (MNVs), defined as two or more nearby variants existing on the same haplotype in an individual, are a clinically and biologically important class of genetic variation. However, existing tools typically do not accurately classify MNVs, and understanding of their mutational origins remains limited. Here, we systematically survey MNVs in 125,748 whole exomes and 15,708 whole

The magnetic susceptibility of lanthanide-chelating bicelles was selectively enhanced by introducing 3β-amino-5-cholestene (aminocholesterol, Chol-NH2) in the bilayer. Unprecedented magnetic alignment of the bicelles was achieved without altering their size. An aminocholesterol conjugate (Chol-C2OC2-NH2), in combination with different lanthanide ions, offers the possibility of fine-tuning the bice

En omfattande syntes av hittillsvarande forskning om Uppåkra.

Den tredje februari 2022 anordnades en workshop vars syfte var att diskutera policy rekommendationer som skulle kunna främja utvecklingen av energigemenskaper i Sverige. Under workshopen diskuterades energigemenskapers möjlighet att äga nät, incitamentsstruktur för att utveckla energigemenskaper och huruvida energiföretag bör tillåtas vara medlemmar i energigemenskaper. Deltagarna i workshopen var

BACKGROUND: Asthma is the most frequent chronic disease in children. One of the most replicated genetic findings in childhood asthma is the ORMDL3 gene confirmed in several GWA studies in several paediatric populations.OBJECTIVES: The purpose of this study was to analyse ORMDL3 variants and expression in childhood asthma in the Polish population.MATERIALS AND METHODS: In the study we included 416

BackgroundHypoplastic left heart syndrome is associated with significant morbidity and mortality. We aimed to assess the influence of left ventricular morphology and choice of shunt on adverse outcome in patients with hypoplastic left heart syndrome and stage 1 palliation.Methods and ResultsThis was a retrospective analysis of patients with hypoplastic left heart syndrome with stage 1 palliation b

Climate change is a physical reality, demanding political and practical solutions. But its inner dimension, overlooked entirely by mainstream approaches, is a human crisis of relationship. This report outlines the relevance of mindfulness and compassion practices in addressing the endemic disconnection from self, others and nature at the root of the climate crisis.We explore the cognitive and emot

In speaking with youth leaders of the Tishreen movement from various cities across the country, what becomes obvious is that while the large lines of national renewal are agreed upon – the need for a new Iraqi identity and new basis for Iraqi nationalism, radical transformation in the practice of power – important points of fracture in their own vision as well as methods for achieving change can b

As an open integrated environment deployed with wired and wireless infrastructures, the smart city heavily relies on the wireless-optical broadband access network. Smart home data are usually sent to neighbor optical network units (ONUs) through front-end wireless mesh networks (WMNs) and finally reach the optical line terminal (OLT) for decision making via the passive optical network (PON) backha

We perform a systematic ab initio study of the electronic structure of Sr(V,Mo,Mn)O3 perovskites, using the parameter-free GW+EDMFT method. This approach self-consistently calculates effective interaction parameters, taking into account screening effects due to nonlocal charge fluctuations. Comparing the results of a three-band (t2g) description to those of a five-band (t2g+eg) model, it is shown

The solvation and swelling behaviour of three dialkylaminoethyl methacrylate polymer brushes, of varying hydrophobicity, have been investigated using a combination of in situ ellipsometry and a quartz crystal microbalance with dissipation (QCM-D). At low pH the tertiary amine groups of the three polymers are protonated and all three brushes are significantly solvated and swell by adopting an exten

The luminosity monitor LUCID (LUminosity Cherenkov Integrating Detector) employed in the ATLAS experiment at the LHC had to be upgraded for the second run of LHC (Run 2) that started in spring 2015. The increased energy of the proton beams and the higher luminosity implied that the Photomultipliers of the original LUCID detector had to be replaced for Run 2 to cope with the more demanding conditio