Insulin-like growth factor-1 (IGF-1) is essential for normal brain development and regulates essential processes of vascular maturation and stabilization. Importantly, preterm birth is associated with reduced serum levels of IGF-1 as compared to in utero levels. Using a preterm rabbit pup model, we investigated the uptake of systemic recombinant human (rh) IGF-1 in complex with its main binding pr

Första gången Svenska kyrkans matbistånd kartlagts statistiskt och nationellt. Matbistånd är det vanligaste materiella biståndet till personer i ekonomisk utsatthet och hela 86% av församlingarna och pastoraten i Svenska kyrkan arbetar med det. I detta kapitel beskrivs omfattning, frekvens, mottagarens hushålls sammansättning, huvudsakliga grupptillhörighet samt om matbiståndet ansetts ha ökat.This is the first time the Church of Sweden's food aid has been mapped statistically and nationally. Food aid is the most common material aid to people in economic vulnerability and a full 86% of the parishes and pastorates in the Church of Sweden work with it. This chapter describes the extent, frequency, composition of the recipient's household, main group affiliation and whether food aid is con

AIM: To explore HPs' perceptions of working on lifestyle management for patients with early rheumatoid arthritis (RA). METHODS: In this qualitative study, individual interviews were conducted with 20 HPs. Qualitative content analysis was used, and three categories and six subcategories were identified. RESULTS: HPs' perceptions of working on lifestyle management for patients with early RA revealed

Despite the fact that the response of tropical hydroclimate to North Atlantic cooling events during the Heinrich Stadial 1 (HS1) has been extensively studied in African, South American and Indonesia, the nature of such responses remains debated. Here we investigate the tropical hydroclimate pattern over the Indo-Asian-Australian monsoon region during the HS1 by integrating hydroclimatic records, a

OBJECTIVE: To compare the effect of early and late intervention for posthemorrhagic ventricular dilatation on additional brain injury and ventricular volume using term-equivalent age-MRI.STUDY DESIGN: In the Early vs Late Ventricular Intervention Study (ELVIS) trial, 126 preterm infants ≤34 weeks of gestation with posthemorrhagic ventricular dilatation were randomized to low-threshold (ventricular

BackgroundCorrect ABO blood-group matching between donor and patient is crucial for safe transfusions. We investigated the underlying reason causing inconclusive ABO serology in samples referred to our laboratory.Study Design and MethodsFlow cytometric analysis, ABO genotyping, and sequencing were used to characterize ABO-discrepant blood samples (n = 13). ABO gene variants were inserted in a GFP-

This article studies the consequences of adult income resulting from exposure to poverty at the neighbourhood and family levels for children aged 1-17 in Southern Sweden from 1947 to 1967. We used geocoded information at the address level to identify k-neighbourhoods of various sizes and applied both relative and absolute poverty measurements, all yielding similar results. Moreover, our longitudin

Background and Objective: Growing evidence shows that certain acute exposures, especially alcohol, may trigger episodes of paroxysmal atrial fibrillation (AF). However, there is a lack of methods for assessing the relation between triggers and AF episodes in individual patients. The present paper proposes an approach to identifying AF triggers based on the assumption that the post-trigger AF burde

A conversational program, MAGROR, for storm water run-off is described. Such programs are necessary for practical engineering purposes related to storm water run-off. The program will assess storm water run-off and recommend optimal pipe dimensions. The program has an automatic capability. The principle of a connecting system for run-off piping is shown schematically. Theoretical considerations ar

Mixtures between choline and geranic acid (CAGE) have previously been shown to insert into lipid bilayers. This may be useful for the transdermal delivery of larger pharmaceuticals, however, little is known about the mechanism of activity. By comparing the interactions between CAGE and lipid bilayers with those of a less-active, yet closely-related analogue, choline octanoic acid (CAOT), a chemica

Presented at the 7th International Conference on Mechanical Behaviour of Materials, The Netherlands, May 1995.

Social and economic change in the built environment is increasingly driven by processes of datafication. These often find expression through smart phone apps and private platforms that seek to upset the status quo by mediating consumer and producer interactions, and by monetising the data these produce. This paper uses the practice-oriented concept of ‘disruptive data’ to draw attention away from