The general research question of the present study was to assess the impact of visually salient online adverts on children's task-oriented internet use. In order to answer this question as reliably as possible, an experimental study was constructed in which 9-year-old and 12-year-old Swedish children were asked to solve a number of tasks while interacting with a mockup website. In each trial, web

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Controlled vocabularies (CVs), i.e. a collection of predefined terms describing a modeling domain, used for the semantic annotation of data, and ontologies are used in structured data formats and databases to avoid inconsistencies in annotation, to have a unique (and preferably short) accession number and to give researchers and computer algorithms the possibility for more expressive semantic anno

Popular Abstract in Swedish Hur gör bakterier för att komma undan immunförsvaret? Vi har studerat hur en vanligt förekommande bakterie, grupp A streptokocker, gör för att undvika kroppens immunförsvar vid infektion. Vi har upptäckt enzymer som bidrar till bakteriens förmåga att undvika immunförsvaret genom att avväpna antikroppar. De bakteriella enzymerna kan användas i bioteknisk industri och eveA majority of the proteins of the immune system are glycosylated and the glycans of IgG are essential for its functionality. Bacteria display enzymes that modulate the glycans of the immune system to weaken the host defense and favor bacterial survival. In this thesis we aimed at exploring bacterial modulation of host glycosylation in infection and to evaluate the usefulness of bacterial enzymes i

Purpose – To identify and describe the strategic potential of logistics-driven packaging innovation in retail supply chains, and suggest propositions for further research and development, providing practitioners with a better basis on which to make strategic packaging and logistics decisions. Design/methodology/approach – An in-depth case study was conducted at a large global retailer which had im

A 'cap and dip' method of adsorbing ruthenium di-2,2'-bipyridy1-4,4'-dicarboxylic acid diisocyanate (N3 dye) on a rutile TiO2 (110) surface was investigated using pyrocatechol as a capping molecule. This method involves cleaning the rutile surface in ultra-high vacuum (UHV), depositing pyrocatechol onto the surface to 'cap' the adsorption sites, removing from vacuum, 'dipping' in an N3 dye solutio

The Mo2B2Fe-type intermetallic compounds Gd2Cu2In and Gd2Cu2Mg form a complete set of solid solutions Gd2Cu2In1-xMgx. The a lattice parameter, the Weiss constant and the Curie temperature increase with increasing magnesium content in an almost Vegard-like manner, while the c parameter remains almost constant. All members of the solid solutions show ferromagnetism with T(C)s between 114 and 80 K.

In this paper, we present a novel approach for the design of rate-maximizing channel shortening detectors with soft feedback side information for frequency-selective channels. The detector is a soft-input soft-output detector and constitutes one of the components of an iterative receiver. The design optimization is performed from an information-theoretic perspective where we maximize the achievabl

We study simulated annealing algorithms to maximise a function psi on a subset of R-d. In classical simulated annealing, given a current state theta(n) in stage n of the algorithm, the probability to accept a proposed state z at which psi is smaller, is exp(-beta(n+1)(psi(z) - psi (theta(n))) where (beta(n)) is the inverse temperature. With the standard logarithmic increase of (beta(n)) the probab

The resolution and fidelity of global chronostratigraphic correlation are direct functions of the time period under consideration. By virtue of deep-ocean cores and astrochronology, the Cenozoic and Mesozoic time scales carry error bars of a few thousand years (k.y.) to a few hundred k. y. In contrast, most of the Paleozoic time scale carries error bars of plus or minus a few million years (m. y.)

Using double-label in situ hybridization, we have explored the possibility that individual CNS neurones can co-express mRNAs for the high-affinity receptors of brain-derived neurotrophic factor and neurotrophin-3, TrkB and TrkC, respectively. The vast majority of TrkC mRNA-containing neurones in the hippocampal formation and cerebral cortex were also labelled for TrkB mRNA. Cells expressing only T

The therapeutic application of siRNA shows promise as an alternative approach to small-molecule inhibitors for the treatment of human disease. However, the major obstacle to its use has been the difficulty in delivering these large anionic molecules in vivo. In this study, we have investigated whether siRNA-mediated knockdown of p38 MAP kinase mRNA in mouse lung is influenced by conjugation to the

The aim of the present study was to compare cellular and noncellular components of bronchoalveolar lavage fluid (BAL) in a group of children with a diagnosis of chronic diffuse parenchymal lung disease (cDPLD) and a group of children without parenchymal lung disease undergoing BAL for various clinical indications (control group). We evaluated cellular and non-cellular components (total proteins, a