OBJECTIVES: To evaluate how radiographic damage, overall and measured as joint space narrowing score (JSNS) and erosion score (ES), as well as other clinical and laboratory measures, relate to disability and pain in early rheumatoid arthritis (RA).METHODS: An inception cohort of 233 patients with early RA, recruited in 1995-2005, was followed for 5 years. Disability was assessed with the Health As

With the help of sermon manuscripts from the time of the Spanish flu, held within the Church of Sweden, new light is shed on sermons held in the beginning of the Covid-19 pandemic. The comparison shows, among other things, that a shift has been made in how God is portrayed. It also points to some challenging questions about suffering, hope and the role of eternity in preaching today.

Översättning till svenska av den amerikanske poeten Ilya Kaminskys debutdiktsamling Dancing in Odessa (2004).

Measurements of archaeological cereal grains has the potential to improve interpretations of archaeobotanical assemblages and to address a broad range of research questions related to agricultural practices in the past. However, understanding the role of the many factors that can influence the morphometrics of cereal grains is of importance to validate the application of morphometrics in archaeobo

Land-use practices and their intensity along with climatic conditions alter amounts of soil organic carbon content and consequently influence soil microorganisms. However, land-use management, such as crop residue incorporation to soils has a potential to mitigate losses of soil organic carbon and thereafter promote the diversity of soil microorganisms. To gain insight of microbial functional dive

Aggressive pituitary tumors (APT) and pituitary carcinomas (PC) are heterogeneous with regard to clinical presentation, proliferative markers, clinical course and response to therapy. Half of them show an aggressive course only many years after the first apparently benign presentation. APT and PC share several properties, but Ki67 index ≥10% and extensive p53 expression are more prevalent in PCs.

Background: The choice of rhythm control drugs for recurrent atrial fibrillation (AF) remains empirical and is based on the safety profile rather than predicted efficacy. Flecainide is recommended for prevention of AF recurrence in patients without structural heart disease however predictors of treatment success are insufficiently studied. Objective: To assess clinical characteristics associated w

This paper reports on a one-to-one aspect of the articulatory-acoustic relationship, explaining how acoustic segment boundaries are a result of the rapid movements of the active articulators. In the acceleration profile, these are identified as acceleration peaks, which can be measured. To test the relationship, consonant and vowel segment durations are compared to articulatory posture intervals b

In this article, we re-trace the history of the Swedish SF archive and reflect on how this collection of historic newsreels has been reappropriated and remixed throughout more recent media history. In particular, we focus on the work of director and film historian Gardar Sahlberg, who made extensive use of the SF archive, first in a series of documentary films, then in a number of historical TV pr

Ethical and legal questions of robotic personalisation can be addressed in various ways. While seeking to theorise on ethical issues related to robotic personalisation, this paper proposes the concept of necrorobotics in order to target a particular space of personalisation, governed by a variety of norms: death, and the reuse of dead persons data to create robotic agency. Based on recent advancem

Due to electrification, new demands are imposed on gears regarding e.g., quality, noise, lubrication, and gear ratio.Therefore, a better understanding of gearset meshing and operation is needed. Experiments are valuable tools, butalso tend to be cumbersome and time consuming. Moreover, contact pressure cannot be measured satisfactorily.Thus, a simulation tool is needed. In this thesis, an LTCA sim

Background: The combination of infliximab and immunosuppressant therapy is a standard management strategy for patients with Crohn's disease. Concerns regarding the implications of long-term combination therapy provided the rationale for a formal clinical trial of treatment de-escalation. Our aim was to compare the relapse rate and the time spent in remission over 2 years between patients continuin

Background & Aims: Industrial foods have been associated with increased risks of several chronic conditions. We investigated the relationship between the degree of food processing and risks of Crohn's disease (CD) and ulcerative colitis (UC) in the European Prospective Investigation into Cancer and Nutrition cohort. Methods: Analyses included 413,590 participants (68.6% women; mean baseline ag

Background: Accumulation of saturated fatty acids (SFAs) in the liver is known to induce hepatic steatosis and inflammation causing non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Although SFAs have been shown to affect the epigenome in whole blood, pancreatic islets, and adipose tissue in humans, and genome-wide DNA methylation studies have linked epigenetic ch