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Photofragmentation of cyanogen upon carbon and nitrogen K-shell excitation by partial ion yield experiments

Partial ion yield spectroscopy was used to study fragmentation processes in cyanogen after C 1s and N 1s photoexcitation. The interpretation of the core excitation spectrum mostly follows the literature, but the high resolution has in some cases allowed a more detailed assignment. Using the fact that in Rydberg states there is an intensity increase as the fragmentation process becomes more extensi

Liver Fat Content and Hepatic Insulin Sensitivity in Overweight Patients With Type 1 Diabetes

Objectives: Patients with type 1 diabetes mellitus (T1DM) lack the portal/peripheral insulin gradient, which might diminish insulin stimulation of hepatic lipogenesis and protect against development of nonalcoholic fatty liver disease (NAFLD). We compared liver fat content and insulin sensitivity of hepatic glucose production and lipolysis between overweight T1DM patients and nondiabetic subjects.

Beständiga förändringar av säkerhetskulturen

Säkerhet är dynamiskt och speciellt så i komplexa säkerhetskritiska verksamheter. När olyckor och incidenter är sällan förekommande i säkerhetskritiska verksamheter kan det ske en långsam och naturlig erosion av säkerhetsmedvetandet och en organisations beteenden kan börja driva mot säkerhetsmarginalerna. Säkerhetskulturen ses som en stark motriktad kraft i ett sådant händelseförlopp. Att organisa

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The article provides with an overview over female sociability in eighteenth century Sweden.

Common sequence variants on 20q11.22 confer melanoma susceptibility

We conducted a genome-wide association pooling study for cutaneous melanoma and performed validation in samples totaling 2,019 cases and 2,105 controls. Using pooling, we identified a new melanoma risk locus on chromosome 20 (rs910873 and rs1885120), with replication in two further samples (combined P < 1 x 10(-15)). The per allele odds ratio was 1.75 (1.53, 2.01), with evidence for stronger assoc

Rao-Blackwellized Auxiliary Particle Filters for Mixed Linear/Nonlinear Gaussian models

The Auxiliary Particle Filter is a variant of the common particle filter which attempts to incorporate information from the next measurement to improve the proposal distribution in the update step. This paper studies how this can be done for Mixed Linear/Nonlinear Gaussian models, it builds on a previously suggested method and introduces two new variants which tries to improve the performance by u

Theoretical considerations for understanding a Purkinje cell timing mechanism

In classical conditioning, cerebellar Purkinje cells learn an adaptively timed pause in spontaneous firing. This pause reaches its maximum near the end of the interstimulus interval. While it was thought that this timing was due to temporal patterns in the input signal and selective engagement of changes in synapse strength, we have shown Purkinje cells learn timed responses even when the conditio

Heterogeneous genetic profiles in soft tissue myoepitheliomas

Myoepithelioma, mixed tumor and parachordoma are uncommon soft tissue tumors thought to represent morphological variants of a single tumor type. The genetic basis of these neoplasms is poorly understood. However, they morphologically resemble mixed tumor of the salivary glands (also known as pleomorphic adenoma), a tumor characterized by deregulated expression of PLAG1 or HMGA2. To evaluate a poss

A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms

Previously, it was shown that the cell-membrane-expressed glycosphingolipid, globotriaosylceramide (Gb(3)/P-k/CD77), protects against HIV-1 infection and may be a newly described natural resistance factor against HIV infection. We have now investigated the potential of a novel, water soluble, non-toxic and completely synthetic analogue of Gb(3)/P-k (FSL-Gb(3)) to inhibit HIV-1 infection in vitro.

Polyamine Pathway as Drug Target against Malaria

Popular Abstract in English An algae that has lost its ability to do photosynthesis over the last million years and started to feed on human blood causes about 600.000 death every year, a number equals about 8 times Lund’s present population. This evolved algae named Plasmod- ium falciparum causes Malaria, a tropical disease mainly affecting economically weak regions in Africa. Unlike bacteria or Malaria, caused by the protozoan parasite Plasmodium falciparum is responsible for about 600.000 death cases every year. Mainly affected are populations of subtropical countries in Africa and the largest groups of victims are children below the age of 5 years. The fast evolving drug resistances of Plasmodium against the the most pow- erful antimalarials threatens the successful containment of this

Alcohol-based hand-disinfection reduced children's absence from Swedish day care centers

Aim: To determine if the use of alcohol-based hand-disinfection as a complement to regular hand washing at daycare centers (DCCs) can reduce the childhood rate of absenteeism. Methods: Children aged 0-6 years attending DCC were studied in a cluster randomized controlled trial during 30 weeks. Thirty matched pairs of DCCs were included in the study, where one of the DCCs was randomized to intervent

Book Reviews

Martikainen’s aim of the book is to show how the religious scene in Finland has changed over the last twenty years due to migration with focus is on minority religious organizations.

Endoplasmic reticulum stress associated with caspases-4 and-2 mediates korbazol-induced B-chronic lymphocytic leukemia cell apoptosis

Purpose: B-cell chronic lymphocytic leukemia (B-CLL) is an incurable disease that rapidly develops drug resistance. Therefore there is a need for identifying new agents that will improve the therapeutic outcome. Korbazol is a natural product known to exert cytotoxic effect on the in vitro survival of leukemic cells. The aim of this study was to investigate the mechanism of korbazol-induced apoptos

Sensationellt valresultat i Indiens folkrikaste delstat

Efter tre års så kallad djungelregim (jungle raj) under Mulayam Singh Yadavs ledning, återkommer nu dalitledaren Mayawati till makten på eget mandat i Uttar Pradesh, Indiens folkrikaste delstat. I det utdragna valet, vars resultat blev klart den 11 maj 2007, vann hon och hennes parti Bahujan Samaj Party (BSP) en absolut majoritet med 206 mandat i delstatförsamlingen.

Mot en ny arbetsorganisering: en sociologisk studie av några försöksprojekt med flexibla arbetstider och distansarbete inom Malmö kommun

I denna rapport får vi följa sex arbetsplatser inom Malmö kommun som under ett och ett halvt år utprovar olika typer av alternativa arbetstidsmodeller. Inom vård och barnomsorg utprovas flexibla bemanningsscheman, inom VA-service utprövas årsarbetstid och bland socialsekreterare och utredare utprovas distansarbete. Utprovningarna sker inom ramen för kommunens personalpolicy som bl a fokuserar ett